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New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Researchers at the Faculty of Medicine, University of Helsinki, make an unexpected and vital contribution to an international collaborative effort in Parkinson's disease research.

7 Nov 2018

New nuclear medicine tracer could improve diagnosis, treatment of non-small cell lung cancer

Researchers have developed a new nuclear medicine tracer that could improve diagnosis and treatment of non-small cell lung cancer.

7 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Scientists describe novel conjugates made from antibodies and protein inhibitor

Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects--especially when treating tumors. In the journal Angewandte Chemie, scientists have now described novel conjugates made from antibodies and a kinesin spindle protein inhibitor.

31 Oct 2018

Researchers develop new material that improves quality, durability of knee cartilage implants

Researchers of Valencia's Polytechnic University, the University of Notre Dame and the Technological University of Auckland, along with multinational company Zimmer, have developed a new material that improves the quality and durability of the articular cartilage implants used in knee operations.

31 Oct 2018

Researchers examine immune responses to CRISPR-Cas9 gene editing system

The CRISPR-Cas9 gene editing system has been generating excitement within the field of gene therapy, inspiring hopes of molecular tools capable of treating genetic diseases.

30 Oct 2018

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

A new gold standard for electrical measurement in the emerging in vitro world of three dimensional models. That's what Swiss medtech 3Brain has established by partnering with CSEM.

30 Oct 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

New method increases virus production in cells to generate more vectors for gene transfer

Researchers at Tokyo Medical and Dental University have established a method to increase the released lentiviral particles produced by host cells, which will aid the use of the vectors for introducing foreign genes into cells

29 Oct 2018

Validation of non-invasive stent monitoring techniques

Researchers from the Research Institute Germans Trias i Pujol, the Biomedical Research Networking Center on Cardiovascular Diseases, the University of Barcelona and the the Universitat Politècnica de Catalunya have created a new field probe to detect in a non-invasive and non-ionizing way the presence of metallic stents as well as their potential structural failures through microwave spectrometry.

25 Oct 2018

Battling against resistant and sensitive types of influenza A

Another flu season is here, which means another chance for viruses to mutate. Already, most influenza A viruses contain a mutation that confers resistance against one class of antiviral medications, and the bugs are steadily gaining resistance against another class.

25 Oct 2018

Researchers identify a new way to prolong the circulation of cancer-fighting nanoparticles in the bloodstream

For a number of innovative and life-saving medical treatments, from organ replacements and skin grafts to cancer therapy and surgery, success often depends on slipping past or fending off the body's immune system.

24 Oct 2018

Nerve-on-a-chip platform could help improve neuroprosthetic designs

Neuroprosthetics - implants containing multi-contact electrodes that can substitute certain nerve functionalities - have the potential to work wonders.

23 Oct 2018

Prion strain diversity may be greater than previously thought

The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a study published October 18 in the open-access journal PLOS Pathogens by Jason Bartz of Creighton University, and colleagues.

19 Oct 2018

Newly discovered compound shows potential for treating Parkinson's disease

A joint research group centered around Professor Hideyuki Okano and Associate Professor Jun Kohyama, Department of Physiology of the Keio University School of Medicine, together with a research group of Eisai Co., Ltd. has identified a compound that has the potential to be a treatment for Parkinson's disease by using dopaminergic neurons differentiated from induced pluripotent stem (iPS) cells from patients with familial Parkinson's disease.

19 Oct 2018

$11 million NIH grant for Clemson University helps launch new center for musculoskeletal research

With an $11 million grant from the National Institutes of Health Center for Biomedical Research Excellence, Clemson University has launched the South Carolina Center for Translational Research Improving Musculoskeletal Health, or SC-TRIMH, a new research center that will bring together scientists from across South Carolina to change the way musculoskeletal disorders are diagnosed, treated and even studied.

19 Oct 2018

Near infrared spectroscopy technique for accurate evaluation of chondral injuries

Osteoarthritis is a disabling disease characterised by joint pain and restricted mobility, affecting especially the elderly. The disease generally progresses slowly, even over decades.

19 Oct 2018

Using Galleria mellonella to assess acute toxicity of chemicals

TruLarv is considered a non-animal technology in the context of UK animal use regulations where procedures on this species are not regulated.

17 Oct 2018

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

A recent article by a team of international experts on multiple sclerosis (MS) underscores the importance of expanding the knowledge base about the hippocampus in order to better understand the genesis of cognitive deficits and develop new treatment strategies.

17 Oct 2018

Studies demonstrate effect of Ketogenic Diet on cognitive health in animals

We've all experienced a "gut feeling" -- when we know deep down inside that something is true. That phenomenon and others (like "butterflies in the stomach") aptly describe what scientists have now demonstrated: that the gut and the brain are more closely connected than we once thought, and in fact the health of one can affect the other.

12 Oct 2018

in vivo News and Research

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

New nuclear medicine tracer could improve diagnosis, treatment of non-small cell lung cancer

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Scientists describe novel conjugates made from antibodies and protein inhibitor

Researchers develop new material that improves quality, durability of knee cartilage implants

Researchers examine immune responses to CRISPR-Cas9 gene editing system

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

New method increases virus production in cells to generate more vectors for gene transfer

Validation of non-invasive stent monitoring techniques

Battling against resistant and sensitive types of influenza A

Researchers identify a new way to prolong the circulation of cancer-fighting nanoparticles in the bloodstream

Nerve-on-a-chip platform could help improve neuroprosthetic designs

Prion strain diversity may be greater than previously thought

Newly discovered compound shows potential for treating Parkinson's disease

$11 million NIH grant for Clemson University helps launch new center for musculoskeletal research

Near infrared spectroscopy technique for accurate evaluation of chondral injuries

Using Galleria mellonella to assess acute toxicity of chemicals

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

Studies demonstrate effect of Ketogenic Diet on cognitive health in animals

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