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Study explains link between infertility and hyperprolactinaemia

One of the most frequent is the existence of tumours that induce an over-secretion of this hormone. These women present with chronic infertility due to anovulation. Thanks to the work of the Inserm researchers from unit 693 "Steroid receptors: endocrinian and metabolic physiopathology", the intimate mechanism of the hyperprolactinaemia alterations affecting reproduction in mice has been discovered.

19 Oct 2012

TB Alliance and FIND partner to promote development of TB drugs and diagnostics

A new partnership announced today will increase efforts to coordinate the development of complementary novel tools to fight TB, including drug-resistant TB, and identify emerging drug resistance trends around the globe.

19 Oct 2012

Study addresses potential benefits of treating anxiety in coronary artery disease

A study published in the current issue of Psychotherapy and Psychosomatics addresses the potential benefits of treating anxiety in coronary artery disease.

19 Oct 2012

Researchers identify brain mechanisms that regulate cocaine-seeking behavior

Researchers from the University of Wisconsin-Milwaukee (UWM) have identified mechanisms in the brain responsible for regulating cocaine-seeking behavior, providing an avenue for drug development that could greatly reduce the high relapse rate in cocaine addiction.

19 Oct 2012

EHRA ICD for Life Summit to be held in Belgrade, Serbia

An EHRA ICD for Life Summit will be held in Belgrade, Serbia, during 19-20 October, to discuss challenges and unmet needs in Central and Eastern European countries. The Summit is targeted at politicians, health insurance companies, policy makers, representatives of health ministries, arrhythmologists and electrophysiologists.

19 Oct 2012

Research to determine how genes contribute to Type 1 diabetes

Diabetes is a chronic, debilitating disease which affects nearly 26 million Americans. As many as three million people have Type 1 diabetes or juvenile diabetes that usually occurs in children or young adults.

19 Oct 2012

Scientists report on development of new malaria drug

Scientists are reporting development of a new malaria drug that, in laboratory tests, has been twice as effective as the best current medicine against this global scourge and may fight off the disease with one dose, instead of the multiple doses that people often fail to take.

18 Oct 2012

Ustekinumab shows positive results in decreasing debilitating effects of Crohn's Disease

Ustekinumab, an antibody proven to treat the skin condition psoriasis, has now shown positive results in decreasing the debilitating effects of Crohn's Disease, according to researchers at the University of California San Diego, School of Medicine.

18 Oct 2012

Phase 3 study of INLYTA fails to meet primary endpoint in treatment-naïve patients with RCC

Pfizer Inc. announced today that a Phase 3 study of INLYTA (axitinib) did not meet its primary endpoint of demonstrating statistically significantly longer progression-free survival, versus sorafenib, in treatment-naïve patients with advanced renal cell carcinoma.

18 Oct 2012

Chloride-restrictive intravenous fluids reduce risk for kidney injury

The restrictive use of chloride in intravenous fluids reduces the risk for acute kidney injury and renal replacement therapy, research shows.

18 Oct 2012

Attachment and relationship problems in adolescents with anxiety

Adolescents with anxiety disorders have greater attachment disorganization and higher levels of dysfunction in peer relationships compared with individuals without an Axis I diagnosis, US study findings indicate.

18 Oct 2012

Gingival crevicular fluid predicts periodontal attachment loss

Analysis of gingival crevicular fluid using mass spectrometry could be used to predict sites of periodontal attachment loss in individuals undergoing maintenance therapy for periodontitis, report researchers.

18 Oct 2012

Pain relief from palliative RT for bone metastases improves QoL

Cancer patients who experience pain relief after palliative radiation therapy for bone metastases report a better quality of life on specific bone metastases measures than their peers who do not respond to treatment, show study results.

18 Oct 2012

Nonmotor symptoms common in early-stage PD

Nonmotor symptoms occur in nearly all individuals with Parkinson’s disease, Italian study results suggest.

17 Oct 2012

Botulinum treatment benefits in BPH maybe down to placebo effect

Treatment with botulinum toxin has proved no more effective than placebo at reducing symptoms in men with lower urinary tract symptoms due to benign prostate hyperplasia, show study findings.

17 Oct 2012

Quitting smoking may improve HRQoL in advanced lung cancer

The health-related quality of life of patients with advanced-stage lung cancer is worsened if they smoke, report UK researchers.

17 Oct 2012

DNA damage response contains previously unknown components: Study

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida; Duke University; Johns Hopkins University; the Brazilian National Cancer Institute; and the Rio de Janeiro Federal Institute of Education, Science and Technology have discovered that an intricate system to repair DNA damage called the "DNA damage response" (DDR) contains previously unknown components, including proteins that could be targeted as sensitizers for chemotherapy.

17 Oct 2012

Chloride-restrictive intravenous strategy may decrease incidence of AKI among critically ill patients

In a pilot study assessing the effect of different levels of chloride in intravenous fluids administered to critically ill patients in an intensive care unit, restricting the amount of chloride administration was associated with a significant decrease in the incidence of acute kidney injury and the use of renal replacement therapy, according to a study in the October 17 issue of JAMA.

17 Oct 2012

Stat5 protein could serve as biomarker to help guide prostate cancer treatment

Men who had high levels of the activated Stat5 protein in their prostate cancer after a radical prostatectomy were more likely to have a recurrence or die from the disease compared to men who had little to no presence of the growth protein, according to a recent study published in Human Pathology by Jefferson's Kimmel Cancer Center researchers.

17 Oct 2012

FGF21 hormone markedly increases life span in mice

A study by UT Southwestern Medical Center researchers finds that a starvation hormone markedly extends life span in mice without the need for calorie restriction.

17 Oct 2012