Cell Metabolism News and Research

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UT Southwestern researchers discover enzyme that promotes tumor growth

UT Southwestern researchers have found that an enzyme on the surface of some lung cancer cells helps feed the cancer, making it a tempting treatment target.

28 Nov 2018

Citrate-based biomaterial could help in better bone repair

A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to a team of Penn State bioengineers.

27 Nov 2018

Scientists develop method to make radio-controlled enzymes

Scientists developed a method to enhance the activity of enzymes by using radio frequency radiation. The method requires making a special complex consisting of enzymes and magnetic nanoparticles.

22 Nov 2018

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease, which is incredibly common and growing.

16 Nov 2018

Salk researchers solve genetic 'whodunnit' for cancer gene

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer.

8 Nov 2018

Researchers reveal link between autoimmune and cardiovascular disease in mice

People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly.

8 Nov 2018

Weight loss success associated with brain areas involved in self-control

New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control.

19 Oct 2018

Fat tissue could be a source of diabetes, shows new research

A new study by Australian researchers, out today, is challenging what we know about the causes of diabetes. The new research points to fat tissue as a source of disease, and widens our understanding beyond the traditional focus on liver and pancreas as the main culprits.

12 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Mast cells associated with allergies also play key role in survival, study reveals

In a University of California, Irvine-led study, researchers found evidence that mast cells, an important group of immune cells typically associated with allergies, actually enable the body to survive fasting or intense exercise.

12 Oct 2018

Scientists find new way to predict obesity-related disease risk

Scientists at Scripps Research and collaborating corporate and academic partners have found a new way to use distinct molecular "signatures" from people with obesity to predict risk of developing diabetes and cardiovascular disease, an advance that could broaden the way doctors and scientists think about diagnosing and treating disease.

12 Oct 2018

Study shows that one amino acid may produce short-term lowering of glucose levels

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins.

11 Oct 2018

Researchers show possibility to restore insulin cell function in type 2 diabetes

By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease.

8 Oct 2018

Researchers discover previously unknown function of key component in the immune system

The complement proteins that circulate in our blood are an important part of our immune system. They help identify bacteria, viruses and other harmful organisms, making it easier for our white blood cells to find and neutralize dangerous microbes.

5 Oct 2018

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Approximately 1.25 million Americans are living with type 1 diabetes, with an additional 40,000 people newly diagnosed every year.

27 Sep 2018

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

A scientific team found that the CXCL14 protein, associated with tumor progression and organogenesis, causes beneficial effects to metabolic diseases such as obesity and diabetes.

19 Sep 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Researchers find new way to differentiate between active and inactive viruses

Human herpesviruses such as HHV-6 can remain dormant in cells for many years without being noticed. When reactivated, they can cause serious clinical conditions. Researchers from Würzburg have now found a way of differentiating between active and inactive viruses.

14 Sep 2018

Differences in mitochondrial DNA determine severity of heart disease caused by nDNA mutation

Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation.

12 Sep 2018

Study: Health and longevity improves with increased fasting time

Increasing time between meals made male mice healthier overall and live longer compared to mice who ate more frequently, according to a new study published in the Sept. 6, 2018 issue of Cell Metabolism.

7 Sep 2018

Cell Metabolism News and Research

UT Southwestern researchers discover enzyme that promotes tumor growth

Citrate-based biomaterial could help in better bone repair

Scientists develop method to make radio-controlled enzymes

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

Salk researchers solve genetic 'whodunnit' for cancer gene

Researchers reveal link between autoimmune and cardiovascular disease in mice

Weight loss success associated with brain areas involved in self-control

Fat tissue could be a source of diabetes, shows new research

Metabolome tests could be new way to measure obesity and health

Mast cells associated with allergies also play key role in survival, study reveals

Scientists find new way to predict obesity-related disease risk

Study shows that one amino acid may produce short-term lowering of glucose levels

Researchers show possibility to restore insulin cell function in type 2 diabetes

Researchers discover previously unknown function of key component in the immune system

CIRM approves $1.6M grant to help bring human islet-like organoids to diabetic patients

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers find new way to differentiate between active and inactive viruses

Differences in mitochondrial DNA determine severity of heart disease caused by nDNA mutation

Study: Health and longevity improves with increased fasting time

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