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Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name - cell migration inducing and hyaluronan-binding protein, or CEMIP - is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer's disease.

11 Dec 2025

Collaborative project seeks safer therapies for ischemia and reperfusion injury

Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to mitigate tissue and organ damage associated with heart attacks, strokes and traumatic injuries.

10 Dec 2025

Hidden infections may play a key role in driving long COVID symptoms

For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but a group of leading microbiologists think they may have cracked the case.

10 Dec 2025

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents - and they've shown a possible route to reducing its likelihood.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

9 Dec 2025

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

In a major step towards a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to block C. diff's most dangerous toxin.

9 Dec 2025

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.

8 Dec 2025

Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain.

5 Dec 2025

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

5 Dec 2025

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Discover how electron microscopy advances plant and microbial research with expert insights from the John Innes Centre’s bioimaging facility.

From Leica Microsystems GmbH 2 Dec 2025

Mapping SV2A drug binding offers a path to better epilepsy treatments

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

Tiny metal particles can kill cancer cells while leaving healthy cells unharmed

An international research team led by RMIT University have created tiny particles, known as nanodots, made from a metallic compound that can kill cancer cells while leaving healthy cells largely unharmed.

1 Dec 2025

New 10-minute scan shows hidden cause of high blood pressure

A speedy new scan could improve how millions of people with high blood pressure are treated, suggests a new study led by UCL (University College London) researchers.

26 Nov 2025

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Arginine reduced amyloid beta aggregation in vitro and in both Drosophila and AppNL-G-F mouse models of Alzheimer’s disease, leading to fewer dense-core plaques and improved behavior. The study provides preclinical evidence that oral arginine may modulate amyloid pathology, although high dosing requirements and model limitations constrain human translation.

24 Nov 2025

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

Wiley expands its spectral database with over 9.5 million high-quality spectra, enhancing compound identification for researchers in various scientific fields.

From John Wiley and Sons - Scientific Publishers 24 Nov 2025

Kennedy sharpens vaccine attacks, without scientific backing

As the federal government prepares for the next meeting of its Advisory Committee on Immunization Practices, Health and Human Services Secretary Robert F. Kennedy Jr. has intensified his attacks on aluminum vaccine components used in many shots to boost the body's immune response.

24 Nov 2025

Compound News and Research

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Collaborative project seeks safer therapies for ischemia and reperfusion injury

Hidden infections may play a key role in driving long COVID symptoms

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Mapping SV2A drug binding offers a path to better epilepsy treatments

Machine learning tool identifies compounds that induce cancer cells into senescence

Tiny metal particles can kill cancer cells while leaving healthy cells unharmed

New 10-minute scan shows hidden cause of high blood pressure

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Obesity-related metabolic stress may affect brain health far earlier than expected

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

Kennedy sharpens vaccine attacks, without scientific backing

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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