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Computational walking model could help stroke patients achieve optimal recovery

After a stroke, patients typically have trouble walking and few are able to regain the gait they had before suffering a stroke. Researchers funded by the National Institute of Biomedical Imaging and Bioengineering have developed a computational walking model that could help guide patients to their best possible recovery after a stroke.

11 Jan 2017

TSRI scientists receive NIH grants for computational biology research

Three groups at The Scripps Research Institute have been awarded grants from the National Institutes of Health to develop methods for computational modeling and to apply them to cutting-edge systems in biology and health.

10 Nov 2016

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery.

22 Sep 2016

Cryo-EM technique allows researchers to visualize large transcription PICs at near-atomic resolution

An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of California at Berkeley and Northwestern University.

12 May 2016

New EU project aims to develop models that can help predict behavior of cancer-related signaling pathways

A group of scientists at Helmholtz Zentrum München will engage in a new project promoted by the EU. The scientists in the team of Dr. Jan Hasenauer, head of the young investigator group 'Data-driven Computational Modeling' work as part of CanPathPro.

4 May 2016

Brain chemical dopamine plays key role in representing or encoding movement

Princeton University researchers have found that dopamine - a brain chemical involved in learning, motivation and many other functions - also has a direct role in representing or encoding movement. The finding could help researchers better understand dopamine's role in movement-related disorders such as Parkinson's disease.

26 Apr 2016

New study explores mechanisms that control size, shape of tubular organ systems

A new study from the group of Holger Gerhardt in collaboration with Katie Bentley's Lab addresses a long standing question in the wider field of developmental biology and tissue patterning in general, and in the vascular biology field in particular: 'What are the fundamental mechanisms controlling size and shape of tubular organ systems'.

21 Apr 2016

New technologies can improve memory, learning in cognitive deficit patients

People are using brain-machine interfaces to restore motor function in ways never before possible - through limb prosthetics and exoskletons. But technologies to repair and improve cognition have been more elusive. That is rapidly changing with new tools - from fully implantable brain devices to neuron-eavesdropping grids atop the brain - to directly probe the mind.

6 Apr 2016

New model identifies climate change as significant factor for expansion of lone star ticks in Kansas

Researchers in the College of Veterinary Medicine at Kansas State University have validated a model showing growth in Kansas for the habitat of the troublesome lone star tick.

2 Mar 2016

Penn State researchers develop self-powered enzyme pumps

A new way to use the chemical reactions of certain enzymes to trigger self-powered mechanical movement has been developed by a team of researchers at Penn State University and the University of Pittsburgh. A paper describing the team's research, titled "Convective flow reversal in self-powered enzyme micropumps," is published this week in the journal Proceedings of the National Academy of Sciences.

27 Feb 2016

Penn investigators devise new method to map 'transcriptome'

A new way of mapping the "transcriptome" -- the collection of RNA read-outs that are expressed by a cell's active genes -- has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2016

UMass Amherst cognitive neuroscientist receives NSF CAREER award to study brain functions

Cognitive neuroscientist Rosie Cowell at the University of Massachusetts Amherst recently received a five-year, $599,619 CAREER award from the National Science Foundation to develop and test a theory of how memory interacts with fine-grained visual perception and how both brain functions depend on the medial temporal lobe (MTL), which once was thought to be critical for memory but not for visual perception.

29 Jan 2016

Scientists pin down structure of neuronal protein clumps associated with ALS

To create treatments for a disease without any, scientists need to study and understand the driving forces behind the faulty biology. Today, researchers at the University of North Carolina School of Medicine announced the first-ever evidence-based description of the neuronal protein clumps thought to be important in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, a fatal neurodegenerative condition.

29 Dec 2015

Environmental exposures and behaviors contribute to the majority of cancers, study shows

Researchers have found that extrinsic factors such as environmental exposures and behaviors contribute heavily to the development of the vast majority of cancers.

17 Dec 2015

Researchers come up with new design for a better liposome

Using computational modeling, researchers at Carnegie Mellon University, the Colorado School of Mines and the University of California, Davis have come up with a design for a better liposome. Their findings, while theoretical, could provide the basis for efficiently constructing new vehicles for nanodrug delivery.

14 Oct 2015

Roy D. Patterson selected to receive ASA's Silver Medal in Psychological and Physiological Acoustics

Roy D. Patterson, Emeritus Professor at the University of Cambridge, Cambridge, UK, has been named recipient of the Acoustical Society of America's Silver Medal in Psychological and Physiological Acoustics for contributions to understanding pitch and timbre perception, and for computational modeling of auditory representations.

9 Oct 2015

Research: When social isolation pairs with coinfection, diseases can spread faster

Conventional wisdom holds that the more people stay within their own social groups and avoid others, the less likely a small disease outbreak will turn into full-blown epidemic. But this conventional wisdom might be quite wrong, according to two Santa Fe Institute researchers, and the consequences could reach far beyond epidemiology.

26 Sep 2015

Scientists receive $6.4 million NSF grant to study smell navigation

A team of scientists, including a UC Berkeley pioneer in odor mapping, has received a $6.4 million grant from the National Science Foundation to dig deeper into how humans and animals navigate by using their sense of smell and converting odors into spatial information.

26 Sep 2015

New supercomputer models can capture the behavior of human heart valves

New supercomputer models have come closer than ever to capturing the behavior of normal human heart valves and their replacements, according to recent studies by groups including scientists at the Institute for Computational Engineering and Sciences at The University of Texas at Austin and the Department of Mechanical Engineering at Iowa State University.

20 Aug 2015

Two new studies on eosinophilic granulomatosis with polyangiitis selected by Vasculitis Foundation

The Vasculitis Foundation is pleased to announce it has selected two new research studies on eosinophilic granulomatosis with polyangiitis (EGPA) /Churg Strauss for funding in the amount of $98,000.

14 Aug 2015