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HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

New insights into HIV-1 capsid disruption open doors for novel therapies

Announcing a new publication for Acta Materia Medica journal. The HIV-1 capsid protein (CA) plays a crucial role in viral replication by orchestrating nuclear entry through interactions with host nuclear pore complexes (NPCs).

13 May 2025

Readers scrutinize federal cuts and medical debt

The recent KFF Health News article "Beyond Ivy League, RFK Jr.'s NIH Slashed Science Funding Across States That Backed Trump" (April 17) struck a nerve.

13 May 2025

Researchers uncover how Entamoeba histolytica evades the immune system

The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea.

12 May 2025

WHO Results Report 2024 shows progress on global health goals amid financial uncertainties

The World Health Organization (WHO) Results Report 2024, shows progress on global health goals, even in times of growing financial uncertainties.

12 May 2025

Online abuse surges among marginalized young adults in low- and middle-income countries

A major new international study has found that young adults in low- and middle-income countries who are sex workers, gay men, transgender or living with HIV are facing a surge in online abuse - from harassment and blackmail to the non-consensual sharing of intimate images.

12 May 2025

New AI tool predicts viral mutations to help future-proof COVID vaccines

A novel AI-driven method helps scientists stay ahead of viral evolution by engineering synthetic spike proteins that anticipate future SARS-CoV-2 escape mutations, offering a powerful tool to test and strengthen next-generation vaccines.

11 May 2025

Study shows strong COVID immunity from infection and vaccination

A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it.

9 May 2025

Oxford study reveals how COVID-19 vaccines prevent severe illness

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

9 May 2025

WHO and Medicines Patent Pool support Nigerian innovation in health diagnostics

The World Health Organization (WHO) and Medicines Patent Pool (MPP) have today announced a sublicensing agreement between MPP and a Nigerian health technology company – Codix Bio – to start development and manufacturing of rapid diagnostic tests (RDTs) using technology transferred from global in-vitro diagnostics company – SD Biosensor (SDB).

9 May 2025

Long-acting HIV drug emerges from decades of research and advocacy

In the hunt for a remedy, when the baton is passed from dedicated academic scientists to an innovative company to trusted community advocates, outcomes for society can be especially powerful.

8 May 2025

HIV drugs found to significantly reduce Alzheimer's risk in new study

UVA Health scientists are calling for clinical trials testing the potential of HIV drugs called NRTIs to prevent Alzheimer's disease after discovering that patients taking the drugs are substantially less likely to develop the memory-robbing condition.

8 May 2025

Anti-parasitic drug could accelerate the elimination of infection endemic to Africa

Tens of millions of people in Africa are infected by parasitic worms that cause lymphatic filariasis (also called elephantiasis), a disease that leads to severe swelling and deformities of the limbs and genitals.

7 May 2025

Trump policies at odds with ‘make America healthy again’ push

In his March address to Congress, President Donald Trump honored a Texas boy diagnosed with brain cancer. Amid bipartisan applause, he vowed to drive down childhood cancer rates through his "Make America Healthy Again" initiative.

7 May 2025

HIV testing and outreach falter as Trump funding cuts sweep the South

Storm clouds hung low above a community center in Jackson, where pastor Andre Devine invited people inside for lunch. Hoagies with smoked turkey and ham drew the crowd, but several people lingered for free preventive health care: tests for HIV and other diseases, flu shots, and blood pressure and glucose monitoring.

6 May 2025

Breakthrough in labeling TB glycans could lead to faster diagnosis

Tuberculosis, the world's deadliest infectious disease, is estimated to infect around 10 million people each year, and kills more than 1 million annually. Once established in the lungs, the bacteria's thick cell wall helps it to fight off the host immune system.

5 May 2025

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Researchers have developed next-generation rifamycin analogs that effectively kill both replicating and nonreplicating Mycobacterium abscessus while minimizing drug-drug interactions. Lead candidates UMN-120 and UMN-121 showed superior efficacy to current treatments in mouse models and retained potency against M. tuberculosis.

5 May 2025

Anal cancer rates increasing among older white and Hispanic women in the U.S.

Anal cancer has been steadily increasing in the United States, with the biggest jumps among older women, especially white and Hispanic women - a shift that challenges assumptions about high-risk groups and who should be screened, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

Alabama can’t prosecute groups helping patients get abortions elsewhere, judge rules

Reproductive rights groups in Alabama wasted no time resuming their work after a federal judge ruled in early April that the state's attorney general can't prosecute — or threaten to prosecute — people or organizations who help Alabama residents seek an abortion by traveling to another state.

5 May 2025

Where and why men die younger: global data breaks it down

A global study published in PLOS Medicine examined sex-disaggregated data on hypertension, diabetes, and HIV/AIDS across 204 countries. It revealed significant but context-dependent differences in disease burden, care access, and outcomes between males and females.

4 May 2025