Prophylaxis News and Research

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We need to prepare for Monkeypox - now confirmed in 21 countries

Efforts should be made to curb the spread of this virus in order to prevent another pandemic.

25 May 2022

STIs could be prevented with a dose of doxycycline after unprotected sex

A significant proportion of bacterial sexually transmitted infections (STIs) - gonorrhea, chlamydia or syphilis - were prevented with a dose of doxycycline after unprotected sex, according to preliminary results of a clinical trial that closed early because it was very effective for men who have sex with men and transgender women who are living with HIV or are taking HIV pre-exposure prophylaxis (PrEP).

25 May 2022

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

Patients who have suffered from a first episode of unprovoked venous thromboembolism (VTE) have an eight times higher risk of recurrence if they stop treatment after repeated negative D-dimer tests, instead of continuing with low-dose anticoagulant (apixaban).

20 May 2022

Researchers explore COVID-19 vaccination in immunocompromised individuals

A new study discusses the safety and efficacy of the COVID-19 vaccination and potential strategies to optimize protection in patients with impaired immunity.

17 May 2022

NIH awards $11.3 million grant to renew the Einstein-Rockefeller-CUNY Center for AIDS Research

The National Institutes of Health has awarded Albert Einstein College of Medicine a five-year, $11.3 million grant to renew the Einstein-Rockefeller-CUNY Center for AIDS Research and expand its efforts to prevent, treat and cure HIV infection, and thereby reduce the burden of HIV, locally, nationally, and internationally.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Prevalence of low-molecular-weight heparin prescription in pregnant women according to level of venous thromboembolic disease risk

The present study was carried out to determine how often LMWH was prescribed in pregnancy, the risk classification of such women based on the ETV-OBS risk calculator, and how the risk varied with the occurrence of SARS-CoV-2 infection.

2 May 2022

Monoclonal-antibody combination AZD7442 prevents COVID-19

In a recent study published in The New England Journal of Medicine, the researchers examined the monoclonal-antibody combination AZD7442 to prevent coronavirus disease 2019 (COVID-19).

25 Apr 2022

Advancements in HIV science

As far as viruses go, human immunodeficiency virus (HIV) is quite simple. About 100,000 times smaller than a red blood cell, the virus expresses just a dozen proteins, yet it can establish a lifelong infection that, if left untreated, causes acquired immunodeficiency syndrome (AIDS) and death.

20 Apr 2022

RNA interference triggers that target SARS-CoV-2 genome

Researchers screened ribonucleic acid interference against SARS-CoV-2.

18 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

Study explores the antibody evasion pattern of SARS-CoV-2 Omicron sublineages

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8 Apr 2022

Improved seroprevalence and antibody response after third COVID-19 vaccination

Researchers evaluated the immunogenicity of a third COVID-19 vaccination in antibody deficient subjects.

8 Apr 2022

Evaluating the trustworthiness and characteristics of COVID-19-related trial preprints

Researchers investigated the impact and trustworthiness of trial preprints on COVID-19-related decision-making.

7 Apr 2022

Study identifies new risk factors for recovery after reconstructive breast surgery

Factors such as anemia and anticoagulants have more impact on hospitalization time after breast reconstruction than "common" risk factors.

4 Apr 2022

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Researchers analyzed whether repeated vaccinations against COVID-19 increase serological response in non-responding kidney transplant recipients.

29 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

A new study has focussed on conducting a systematic search of the literature and aggregated data associated with randomized control trials of passive antibody therapy.

25 Mar 2022

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Researchers determined the impact of vitamin D status in preventing all-cause acute respiratory infection and SARS-CoV-2 infection.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Prophylaxis News and Research

We need to prepare for Monkeypox - now confirmed in 21 countries

STIs could be prevented with a dose of doxycycline after unprotected sex

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

Researchers explore COVID-19 vaccination in immunocompromised individuals

NIH awards $11.3 million grant to renew the Einstein-Rockefeller-CUNY Center for AIDS Research

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Prevalence of low-molecular-weight heparin prescription in pregnant women according to level of venous thromboembolic disease risk

Monoclonal-antibody combination AZD7442 prevents COVID-19

Advancements in HIV science

RNA interference triggers that target SARS-CoV-2 genome

Immunocompromised hosts with Delta/Omicron co-infections

Study explores the antibody evasion pattern of SARS-CoV-2 Omicron sublineages

Improved seroprevalence and antibody response after third COVID-19 vaccination

Evaluating the trustworthiness and characteristics of COVID-19-related trial preprints

Study identifies new risk factors for recovery after reconstructive breast surgery

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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