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New gene therapy to treat cancer in children, young adults offers hopes and challenges

The first gene therapy for cancer, approved by the Food Drug Administration in August, will transform the treatment of a particular kind of cancer in children and young adults. It's transformative because it uses a patient's own immune cells to attack the cancer cells.

3 Oct 2017

Cancer vaccines need to target immune fighters that can withstand battle against malicious tumors

Cancer vaccines may need to better target T cells that can hold up to the long fight against cancer, scientists report.

27 Sep 2017

UTSA professor awarded grant to support development of prostate cancer detection method

Jing Yong Ye, professor of biomedical engineering at The University of Texas at San Antonio (UTSA), has received a two-year, $354,617 grant from the National Institutes of Health's National Cancer Institute to support the development of his noninvasive method of detecting prostate cancer.

25 Sep 2017

“Super malaria” resistant to standard medications in South East Asia

The spread of a single multidrug resistant malaria parasite strain in Vietnam is cause for alarm say researchers.

25 Sep 2017

Neurohistology: how whole slide scanning impacts workflow

MultiBrain technology can accelerate the R&D preclinical and safety assessment processes many fold and perform them less expensively.

From Huron Digital Pathology 21 Sep 2017

Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body's own capacity to fight malignancies by activating an inflammation process that counter's the ability of cancer cells to evade the immune system.

20 Sep 2017

'Pocket' project develops new low-cost test for accurate TB detection

Tuberculosis (TB) is a major global health issue. According to the World Health Organisation (WHO), every year there are worldwide 8.8 million new active TB cases and nearly 2 million TB deaths - 5000 every day - mostly in the poorest communities of the developing world.

19 Sep 2017

Researchers identify potential gonorrhea vaccine candidates

Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

19 Sep 2017

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Scientists at The Scripps Research Institute have made a discovery that could speed efforts to develop a successful HIV vaccine.

14 Sep 2017

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

The most common test strip people might think of for diagnosis is a home pregnancy test. Pregnant women have steadily increasing levels of the biomarker human chorionic gonadotropin (hCG), which is easily detectable in urine and a thin, colorful strip of antibodies will appear when hCG is present.

13 Sep 2017

‘Nanoswitches’ could be key to faster, more sensitive tests for detection of biomarkers

Engineered strands of DNA -- nanoscale tools called "nanoswitches" -- could be the key to faster, easier, cheaper and more sensitive tests that can enable high-fidelity detection of biomarkers indicating the presence of different diseases, viral strains and even genetic variabilities as subtle as a single-gene mutation.

12 Sep 2017

Researchers reveal new approach to precisely identify and treat prostate cancer

Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects.

7 Sep 2017

Blood tumor markers could be useful in monitoring therapeutic outcomes for lung cancer patients

For many years, oncologists have known that cancers can secrete complex molecules into the blood and that levels of these molecules can be easily measured. These so-called 'tumor markers' are traditionally associated with a single dominant cancer type, for example Prostate Specific Antigen (PSA) linked to prostate cancer, Carcinoembryonic antigen (CEA) to colorectal cancer, CA125 to ovarian cancer, CA19.9 to pancreatic cancer and CA27.29 to breast cancer.

6 Sep 2017

New portable allergen-detection system could help prevent trips to emergency room

For kids and adults with food allergies, a restaurant outing can be a fraught experience. Even when care is taken, freshly prepared or packaged meals can accidentally become cross-contaminated with an offending food and trigger a reaction.

6 Sep 2017

Prostate cancer screening reduces cancer deaths finds new analysis

There has been much debate regarding the utility of prostate cancer screening in reducing the rates of deaths due to this cancer among men. While the ERSPC (European Randomized Study of Screening for Prostate Cancer) suggests that screening reduced prostate cancer deaths, the PLCO (Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial) found that regular screening does not reduce the cancer death rates in prostate cancer. Researchers thus looked at the actual picture as to which of these – ERSPC or PLCO are correct.

5 Sep 2017

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML).

1 Sep 2017

Pfizer receives FDA approval for new therapy to treat adults and children with AML

Pfizer Inc. today announced that the U.S. Food and Drug Administration approved MYLOTARG (gemtuzumab ozogamicin) for adults with newly diagnosed CD33-positive acute myeloid leukemia (AML), and adults and children 2 years and older with relapsed or refractory CD33-positive AML.

1 Sep 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

Researcher uses gold nanoparticles and lasers to target bladder cancer

A University of Colorado Cancer Center study takes a new approach to killing cancer: Why not fry it into oblivion with vibrating gold nanoparticles? "But what about the frickin' lasers?" you may ask. Don't worry. There are lasers. And bioluminescence too.

31 Aug 2017

Antigen News and Research

New gene therapy to treat cancer in children, young adults offers hopes and challenges

Cancer vaccines need to target immune fighters that can withstand battle against malicious tumors

UTSA professor awarded grant to support development of prostate cancer detection method

“Super malaria” resistant to standard medications in South East Asia

Neurohistology: how whole slide scanning impacts workflow

Researchers design novel small antibody fragment with improved crystallizability

Poliovirus therapy triggers longer-lasting immune response against malignant tumors

'Pocket' project develops new low-cost test for accurate TB detection

Researchers identify potential gonorrhea vaccine candidates

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Nanoparticle bling could increase sensitivity of test strips for better cancer detection

‘Nanoswitches’ could be key to faster, more sensitive tests for detection of biomarkers

Researchers reveal new approach to precisely identify and treat prostate cancer

Blood tumor markers could be useful in monitoring therapeutic outcomes for lung cancer patients

New portable allergen-detection system could help prevent trips to emergency room

Prostate cancer screening reduces cancer deaths finds new analysis

FDA approves drug to treat patients with newly diagnosed CD33-positive AML

Pfizer receives FDA approval for new therapy to treat adults and children with AML

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

Researcher uses gold nanoparticles and lasers to target bladder cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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