Clinical Trial News and Research

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No improvement in freedom from progression rates for patients: Study

Results from the NRG Oncology NRG-RTOG 0232 clinical trial adding external beam radiotherapy (EBRT) to brachytherapy (BT) in men with intermediate-risk prostate cancer indicate that there was no improvement in freedom from progression (FFP) rates for patients.

16 Jun 2023

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

16 Jun 2023

Teaching pupils about mental health can have a positive impact on young people's wellbeing

Giving schools the right resources and training to teach pupils about mental health really can have a positive impact on young people's wellbeing.

15 Jun 2023

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

A promising emerging treatment (hypercapnia) for comatose adult cardiac arrest patients has been found to yield similar results to current treatment, in a new study published today in the prestigious medical journal New England Journal of Medicine.

15 Jun 2023

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Clinical stage generative artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico") has announced a new multimodal transformer-based aging clock that is capable of processing diverse data sets and providing insights into biomarkers for aging, mapping them to genes relevant to both aging and disease, and discovering new therapeutic targets designed to slow or reverse both aging and aging-related diseases.

15 Jun 2023

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

Researchers performed a double-blinded, phase III randomized trial.

15 Jun 2023

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

15 Jun 2023

Phone menu test assesses daily functioning in people at risk of developing Alzheimer's disease

A new study by investigators from Mass General Brigham has found that a brief, simulated task of navigating a phone menu can detect the earliest changes in daily functioning in people at risk of developing Alzheimer's disease.

14 Jun 2023

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study.

14 Jun 2023

Landmark study in trauma care shines new light on tranexamic acid

A new study from Australia, New Zealand and Germany published in the New England Journal of Medicine raises important questions about the success or otherwise of emergency medicine.

14 Jun 2023

Limiting social media use provides psychological benefits

Last month, the American Psychological Association and the U.S. Surgeon General both issued health advisories.

14 Jun 2023

Maximizing the function and potential of stem cell-based treatments for patients with Type 1 diabetes

Following encouraging results from pre-clinical research and a recent clinical trial on stem cell-based treatments for patients with Type 1 diabetes, researchers are now working on maximizing the function and potential of stem cell-based treatments for future application in patients.

13 Jun 2023

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute.

13 Jun 2023

Carb conundrum: debunking the link between pasta and obesity

Researchers reviewed existing data on the impact of diet patterns with high pasta content on body weight.

13 Jun 2023

Cracking the code: omega-3 and omega-6 fatty acids' impact on glucose metabolism

Researchers explored the impact of omega-3 and -6 fatty acids on glucose metabolism.

13 Jun 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin, a widely available oral medication, reduces SARS-CoV-2 viral load by 3.6-fold in outpatient trial, offering a potential treatment option. Ivermectin and fluvoxamine show no significant virologic effect.

12 Jun 2023

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Researchers from five colleges at Rochester Institute of Technology are testing a new way to deliver mental health therapy to people struggling with alcohol/drug addiction and aggressive behavior.

12 Jun 2023

Researchers identify a potential breakthrough in glioblastoma treatment

In a recently published manuscript, Howard Colman, MD, PhD, Jon M. Huntsman Presidential Professor of Neuro-Oncology and co-leader of the Neurologic Cancers Disease Center and the Experimental Therapeutics CCSG program at Huntsman Cancer Institute, identified a potential breakthrough in glioblastoma treatment.

12 Jun 2023

Clinical Trial News and Research

No improvement in freedom from progression rates for patients: Study

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

Teaching pupils about mental health can have a positive impact on young people's wellbeing

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Phone menu test assesses daily functioning in people at risk of developing Alzheimer's disease

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Landmark study in trauma care shines new light on tranexamic acid

Limiting social media use provides psychological benefits

Maximizing the function and potential of stem cell-based treatments for patients with Type 1 diabetes

Repeat intraocular corticosteroid injections improve vision in people with persistent or recurrent uveitic macular edema

Carb conundrum: debunking the link between pasta and obesity

Cracking the code: omega-3 and omega-6 fatty acids' impact on glucose metabolism

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

Metformin shows promising antiviral activity against SARS-CoV-2

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Researchers identify a potential breakthrough in glioblastoma treatment

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