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Researchers explore influence of dietary nitrate on cognitive function in veterans with GWI

Glenn Wylie, DPhil, and Jorge Serrador, PhD, have won an award from the Rutgers Brain Health Institute. The grant funds a collaborative study between the Department of Pharmacology, Physiology, and Neuroscience at Rutgers New Jersey Medical School and Kessler Foundation.

1 Aug 2018

FDA approves first therapy for patients with rare tumors of the adrenal gland

The U.S. Food and Drug Administration today approved Azedra (iobenguane I 131) injection for intravenous use for the treatment of adults and adolescents age 12 and older with rare tumors of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumor site and require systemic anticancer therapy.

31 Jul 2018

New findings suggest opportunity to focus on safe opioid use and disposal among older adults

Nearly a third of older adults have received a prescription for an opioid pain medicine in the past two years, but many of them didn't get enough counseling about the risks that come with the potent painkillers, how to reduce their use, when to switch to a non-opioid option, or what to do with leftover pills, a new poll finds.

30 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Fitness trackers can be valuable tools for monitoring cancer patients, finds study

Fitness trackers can be valuable tools for assessing the quality of life and daily functioning of cancer patients during treatment, a new study has found.

25 Jul 2018

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

The governing board of the California Institute for Regenerative Medicine unanimously approved this week two grants worth more than $2.2 million to University of California San Diego School of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.

20 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Early surgical intervention may improve outcomes for patients with mitral valve disease

The number of patients undergoing mitral valve operations are at an all-time high, and new research posted online today in The Annals of Thoracic Surgery suggests that many patients don't undergo surgical intervention until it's too late to completely reverse damage caused by mitral valve disease.

19 Jul 2018

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

The U.S. Food and Drug Administration today approved Kisqali (ribociclib) in combination with an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy.

19 Jul 2018

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

A fatal neurodegenerative condition known as Gaucher disease can be prevented in mice following fetal gene therapy, finds a new study led by UCL, the KK Women's and Children's Hospital and National University Health System in Singapore.

16 Jul 2018

UW-Madison researchers develop new method to track Parkinson's damage in the heart

A new way to examine stress and inflammation in the heart will help Parkinson's researchers test new therapies and explore an unappreciated way the disease puts people at risk of falls and hospitalization.

13 Jul 2018

Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome.

10 Jul 2018

Forest ecosystem influences tick-borne disease risk in the eastern US

In the eastern US, risk of contracting Lyme disease is higher in fragmented forests with high rodent densities and low numbers of resident fox, opossum, and raccoons.

10 Jul 2018

New trial to evaluate whether fasting can improve MS symptoms

People with multiple sclerosis (MS) can find an abundance of conflicting advice suggesting that special diets – everything from avoiding processed foods to going low-carb – will ease their symptoms. But the evidence is scanty that dietary changes can improve fatigue or other MS symptoms.

10 Jul 2018

Car vibrations are the culprit that makes drivers sleepy finds study

Long drives and long car journeys can make a person sleepy. While driving this is one of the commonest reasons for accidents with one in five accidents occurring due to sleepiness or fatigue behind the wheels.

9 Jul 2018

Study: Physician burnout equally responsible for medical errors as unsafe healthcare settings

Physician burnout is at least equally responsible for medical errors as unsafe medical workplace conditions, if not more so, according to a study led by researchers at the Stanford University School of Medicine.

9 Jul 2018

Depression and anxiety in heart failure patients linked to adverse outcomes

Symptoms of depression and anxiety are present in about one-third of patients with heart failure - and these patients are at higher risk of progressive heart disease and other adverse outcomes, according to a review and update in the July/August issue of Harvard Review of Psychiatry.

6 Jul 2018

Fatigue News and Research

Researchers explore influence of dietary nitrate on cognitive function in veterans with GWI

FDA approves first therapy for patients with rare tumors of the adrenal gland

New findings suggest opportunity to focus on safe opioid use and disposal among older adults

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

CNDA approves KEYTRUDA for treatment of advanced melanoma

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Fitness trackers can be valuable tools for monitoring cancer patients, finds study

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Early surgical intervention may improve outcomes for patients with mitral valve disease

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease

UW-Madison researchers develop new method to track Parkinson's damage in the heart

Study identifies constellation of metabolites linked to ME/CFS

Forest ecosystem influences tick-borne disease risk in the eastern US

New trial to evaluate whether fasting can improve MS symptoms

Car vibrations are the culprit that makes drivers sleepy finds study

Study: Physician burnout equally responsible for medical errors as unsafe healthcare settings

Depression and anxiety in heart failure patients linked to adverse outcomes

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