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Erlotinib increases survival in patients with advanced non-small cell lung cancer

An international clinical study led by Canadian researchers has demonstrated that a drug called erlotinib increases survival in patients with advanced non-small cell lung cancer who typically have no other treatment options.

13 Jul 2005

Sirna Therapeutics granted new UK patents

Sirna Therapeutics has announced that the United Kingdom (UK) Patent Office has granted the Company two additional short interfering RNA (siRNA) target patents. The first patent covers any siRNA with one or more chemical modifications targeting Vascular Endothelial Growth Factor (VEGF).

12 Jul 2005

Urine testing may predict birthmarks

Vascular anomalies - birthmarks caused by abnormal development of arteries, capillaries, veins or lymph vessels - can sometimes begin to progress, requiring aggressive treatment to save the child's health or vision. Research at Children's Hospital Boston now suggests that urine testing can help monitor these anomalies and predict those about to become a serious threat.

6 Jul 2005

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

What do you get when you mix RNA chips and zebrafish? A new two-stage method for studying human gene expression differs in human stem cells and progenitor cells, according to a new article in the open access journal PLoS Biology.

6 Jul 2005

RxKinetix receives grant to develop thermostable vaccines with improved stability at non-refrigerated temperatures

RxKinetix Inc., a specialty pharmaceutical company has received a grant offer from the prestigious Grand Challenges in Global Health initiative. The grant will be used to develop thermostable vaccines with improved stability at non-refrigerated temperatures for use in the world's poorest countries.

30 Jun 2005

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

...a discovery that could help in the design of more targeted treatments for patients with various lung diseases, including cystic fibrosis.

30 Jun 2005

Researchers use PET/CT for molecular imaging of the heart

For the first time, researchers used positron emission tomography (PET)/computed tomography (CT) for imaging the subcellar function of the heart - from its subcellular function to its morphologic appearance. The results of the study were reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

For years, a major obstacle has dashed the hopes of creating "replacement parts" for the human body: the lack of an internal, nourishing blood system in engineered tissues. Without it, thicker tissues can't thrive, which has confined tissue engineering's practical application to thin skin, which can recruit blood vessels from underlying tissue.

20 Jun 2005

Study examines biomarkers for response to erlotinib in glioma

Researchers have found two biomarkers that, in patients with a malignant type of brain tumor called glioblastoma multiforme, were associated with response to the cancer drug erlotinib (Tarceva).

14 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Molecule called Smad7 may open doors to future treatments in pancreatic and other forms of cancer

Making new strides in their ongoing effort to understand mechanisms behind the relentless growth of cancer cells, researchers at Dartmouth Medical School have found a promising key that may open doors to future treatments in pancreatic and other forms of cancer.

9 Jun 2005

IGF-based growth hormone dosing could become a novel paradigm in treating growth hormone deficiency

A randomized University of California - Los Angeles (UCLA) study found that a new dosing paradigm can improve height outcomes in the treatment of children who have short stature due to growth hormone deficiency and idiopathic short stature.

6 Jun 2005

Suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer

A modest suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer, researchers from Wake Forest University School of Medicine and other centers reported today at ENDO 2005, the annual meeting of the Endocrine Society, in San Diego.

5 Jun 2005

Chemo combo increases breast cancer survival

A new Spanish study has found that a combination of chemotherapy drugs can increase the five-year survival rate of women with metastatic, node-positive breast cancer by 7 percent.

2 Jun 2005

New approach to inhibiting blood vessel growth or angiogenesis

A manmade protein with a tail of amino acids delivered to target cells can dramatically reduce blood vessel growth that obstructs vision or feeds a tumor, researchers have found.

31 May 2005

Cetuximab (Erbitux) can battle cancer and prolong life in many patients with advanced colorectal cancer

"Even in people who have gone through six or more previous courses of chemotherapy, cetuximab, may fight the growth of cancer, giving patients additional months of life," says study presenter Heinz-Josef Lenz, M.D., associate professor of medicine at the Keck School of Medicine of the University of Southern California and USC/Norris Comprehensive Cancer Center.

20 May 2005

New drug combination prevents breast cancer growth pre-surgery

A new type of drug originally developed for lung cancer can reduce the size of breast cancer tumours when taken in combination with other drugs.

17 May 2005

Gefitinib (Iressa) could reduce the size of breast cancer tumours

Giving women with early breast cancer a drug called gefitinib (Iressa) before surgery could reduce the size of their tumours, suggests a randomised trial published online today by The Lancet Oncology.

17 May 2005

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications.

17 May 2005

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Growth Factor News and Research

Erlotinib increases survival in patients with advanced non-small cell lung cancer

Sirna Therapeutics granted new UK patents

Urine testing may predict birthmarks

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

RxKinetix receives grant to develop thermostable vaccines with improved stability at non-refrigerated temperatures

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

Researchers use PET/CT for molecular imaging of the heart

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

Study examines biomarkers for response to erlotinib in glioma

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Molecule called Smad7 may open doors to future treatments in pancreatic and other forms of cancer

IGF-based growth hormone dosing could become a novel paradigm in treating growth hormone deficiency

Suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer

Chemo combo increases breast cancer survival

New approach to inhibiting blood vessel growth or angiogenesis

Cetuximab (Erbitux) can battle cancer and prolong life in many patients with advanced colorectal cancer

New drug combination prevents breast cancer growth pre-surgery

Gefitinib (Iressa) could reduce the size of breast cancer tumours

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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