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Research shows clopidogrel as better long-term therapy than aspirin after PCI

People at high risk for recurrent cardiac events following percutaneous coronary intervention (PCI), a procedure to open blocked arteries, experienced significantly better outcomes with clopidogrel rather than aspirin as their long-term antiplatelet therapy, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Study finds high rates of undiagnosed and untreated peripheral artery disease

A new Intermountain Health study finds that peripheral artery disease, a condition that affects more than 10 million Americans over the age of 40, is often underdiagnosed and undertreated, with fewer women getting guideline-directed medical therapy than men.

31 Mar 2025

AI model matches high-sensitivity troponin testing in diagnosing heart attacks

An artificial intelligence (AI) model trained to detect blocked coronary arteries based on electrocardiogram (ECG) readings performed better than expert clinicians and was on par with troponin T testing, according to research presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

New trial shows oral semaglutide reduces cardiovascular events in diabetes patients

Both the injectable and oral forms of semaglutide, a glucagon-like peptide-1 receptor agonist, have gained recent attention for their effectiveness against weight gain, high blood sugar, and even alcohol cravings.

31 Mar 2025

WARRIOR trial finds no impact of intensive therapy on heart events in women

An intensive three-drug regimen of heart medications did not significantly impact the rate of serious cardiovascular events at five years in women who experienced signs and symptoms of ischemia, or insufficient blood flow to the heart muscle, but had no blockages in their heart's arteries, according to research presented at the American College of Cardiology's Annual Scientific Session.

29 Mar 2025

Bentracimab reverses ticagrelor's antiplatelet effects during surgery and bleeding events

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's antiplatelet effects in patients undergoing urgent surgery or experiencing major bleeding, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Semaglutide, a glucagon-like peptide 1 (GLP-1) agonist, significantly improved maximal walking distance in people with symptomatic peripheral artery disease (PAD) and Type 2 diabetes in the first-of-its kind trial to evaluate the use of a GLP-1 agonist to manage PAD.

29 Mar 2025

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Research reveals optimal duration of dual antiplatelet therapy after stent implantation

Patients who have a stent implanted to open a blocked coronary artery face dual risks of developing blood clots and of having excessive bleeding in the months following the procedure.

29 Mar 2025

New ESC consensus statement advances conduction system pacing therapy

The European Society of Cardiology (ESC) has released a groundbreaking consensus statement on conduction system pacing (CSP), marking a significant milestone in the evolution of pacing therapy.

29 Mar 2025

New phospholipids improve functional mRNA delivery via lipid nanoparticles

Researchers develop innovative phospholipids that improve the functional delivery of mRNA via lipid nanoparticles, paving the way for advanced therapeutic applications.

28 Mar 2025

Lipid accumulation in tumors linked to therapy resistance in breast cancer

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy.

28 Mar 2025

Study finds 24-hour fasting cycles enhance libido in male mice

Long-term fasting in 24-hour cycles increases the sex drive of male mice by lowering the concentration of the neurotransmitter serotonin in the brain.

28 Mar 2025

AI-powered model improves prediction of bladder cancer treatment outcomes

Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy.

28 Mar 2025

Interval cancers account for significant breast cancer cases

In a new study, researchers from Karolinska Institutet have shown that so-called interval cancers, which are detected between two screening sessions, account for a significant proportion of breast cancer cases and that certain risk factors may increase the likelihood of developing this type of cancer.

28 Mar 2025

Their physical therapy coverage ran out before they could walk again

Mari Villar was slammed by a car that jumped the curb, breaking her legs and collapsing a lung. Amy Paulo was in pain from a femur surgery that wasn't healing properly.

28 Mar 2025

Gender affirming hormone therapy reduces HIV risk for transgender people

Transgender people receiving gender-affirming hormone therapy have a 37% lower chance of acquiring HIV, and for people living with HIV, hormone therapy appears to offer a 44% lower chance of the virus remaining detectable in blood, according to a University of Michigan study.

27 Mar 2025

New medical database enhances obesity research and treatment

A new medical database automatically compiles the medical records of obese patients and those suffering from obesity-related diseases in a uniquely comprehensive and reliable manner.

27 Mar 2025

Study reveals progressive breast shrinkage after breast-conserving therapy

For women with early-stage breast cancer, breast-conserving therapy (BCT) including radiation therapy (RT) leads to progressive reduction in breast size over time, reports a study in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

27 Mar 2025

Digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued.

27 Mar 2025