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Bipartisan obesity bill gains support from Endocrine Society

The Endocrine Society today endorsed the introduction of the bipartisan Treat and Reduce Obesity Act (TROA) in the Senate.

5 Jun 2025

Study challenges taurine as a biomarker of aging

Research in animals and humans has suggested low levels of taurine may be a driver for aging, which has led to discussions about whether taurine is an aging biomarker.

5 Jun 2025

Tumor profiling study advances personalized cancer treatment

Every tumor is unique. This makes it difficult to find the most effective therapy for treatment. The Tumor Profiler Center of the University Hospital Zurich, the University of Zurich, ETH Zurich and the University Hospital Basel has now carried out a study in which nine different molecular biological technologies were used to precisely measure the properties of the tumor in four weeks and enable a precise treatment decision.

5 Jun 2025

Alzheimer's gene therapy could help protect the brain from damage and preserve cognitive function

Researchers at University of California San Diego School of Medicine have developed a gene therapy for Alzheimer's disease that could help protect the brain from damage and preserve cognitive function.

5 Jun 2025

Using Swarm Learning approach to aid doctors in treating stroke patients

Researchers at DZNE and the Department of Vascular Neurology at the University Hospital Bonn (UKB) aim to develop a computer model based on artificial intelligence (AI) to aid doctors in treating stroke patients.

5 Jun 2025

Loss of Y chromosome in male immune cells linked to poorer cancer outcomes

A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune system function, which may explain why loss of Y is associated with lower cancer survival rates.

5 Jun 2025

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a study published by The BMJ today.

5 Jun 2025

Talking therapy boosts recovery in stroke survivors with depression or anxiety

Stroke survivors with depression or anxiety who attend talking therapy sessions are more likely to recover from their psychological symptoms, finds a new study by UCL researchers.

5 Jun 2025

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

5 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

FDA approves ENCELTO implant to preserve sight in people with macular telangiectasia type 2

For people diagnosed with macular telangiectasia type 2 (MacTel)-a rare and slowly progressing retinal disease-there have been no FDA-approved (or other) treatments to slow or stop vision loss.

4 Jun 2025

Y chromosome loss linked to poor cancer outcomes

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

An Arm and a Leg: A mathematical solution for US hospitals?

What do the KGB and the former CEO of Cincinnati Children’s Hospital have in common?

4 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Early camizestrant therapy keeps advanced breast cancer in check

Switching to camizestrant, a next-generation oral SERD, significantly prolongs progression-free survival and maintains quality of life in patients with ESR1-mutated, hormone receptor-positive advanced breast cancer. The proactive, biomarker-guided approach allows earlier intervention and may redefine standard care.

3 Jun 2025

Therapy News and Research

Bipartisan obesity bill gains support from Endocrine Society

Study challenges taurine as a biomarker of aging

Tumor profiling study advances personalized cancer treatment

Alzheimer's gene therapy could help protect the brain from damage and preserve cognitive function

Using Swarm Learning approach to aid doctors in treating stroke patients

Loss of Y chromosome in male immune cells linked to poorer cancer outcomes

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Talking therapy boosts recovery in stroke survivors with depression or anxiety

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

FDA approves ENCELTO implant to preserve sight in people with macular telangiectasia type 2

Y chromosome loss linked to poor cancer outcomes

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Key proteins and pathways drive the success of CAR-T cell therapy

An Arm and a Leg: A mathematical solution for US hospitals?

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

Navigating the dual role of B cells in tumor immunity

Early camizestrant therapy keeps advanced breast cancer in check

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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