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Transplanted beta cells protect themselves by adapting to their new homes

For transplanted beta cells, life is tough. Not only are the insulin-producing cells in a stranger's body, tucked into the liver rather than the pancreas, they are a bit short on oxygen and blood, and they are often exposed to raised levels of glucose.

3 Jul 2010

Web sites that promote anorexia raise concern

For women with low self-esteem, poor body image and a certain genetic predisposition towards an eating disorder, the messages promoted on pro-eating disorder web sites can be similar to someone considering suicide finding a loaded gun on her pillow.

3 Jul 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Mount Sinai Hospital researchers including Drs. Andras Nagy and Jeff Wrana have discovered new insights into the genesis of stem cells, which will improve the efficiency of stem cell creation for use in tissue regeneration and in the development of new drugs.

3 Jul 2010

Pennsylvania Department of Health announces new study on blood disorder Polycythemia vera

The Pennsylvania Department of Health today announced a new, federally-funded study on the blood disorder Polycythemia vera, or PV, in Bedford, Blair, Cambria and Somerset counties.

3 Jul 2010

First US forum gathers doctors and children who no longer need insulin

Twenty-five families who have overcome diabetes caused by a defect in a single gene will gather at "Celebrating the Miracles," a University of Chicago symposium for patients, parents and physicians. The first Monogenic Diabetes Forum is designed to review scientific studies, celebrate treatment successes, stress the importance of a genetic diagnosis for children diagnosed before age one, and exchange tips on how to make the most of a new concept--life without insulin injections.

3 Jul 2010

Eli Lilly, Alnara sign definitive merger agreement

Eli Lilly and Company and Alnara Pharmaceuticals, Inc. today announced they have signed a definitive merger agreement whereby Lilly will acquire Alnara, a privately held biotechnology company developing protein therapeutics for the treatment of metabolic diseases. Alnara's lead product in development is liprotamase, a non-porcine pancreatic enzyme replacement therapy (PERT).

2 Jul 2010

PhenotypeIT launches integrated Corporate Health and Wellness Management Platform

PhenotypeIT, Inc. announced today the launch of its PhIT™ platform, the first truly integrated Corporate Health and Wellness Management Platform that predicts disease and chronic health conditions before their onset and provides critical aggregated data to employers to reduce costs. The PhIT platform accurately assesses the impact of current and future health conditions, and assesses the cost implications of these conditions and related loss of productivity for the employer.

2 Jul 2010

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

Utilizing Fluidigm Corporation's Dynamic Array™ and Digital Array™ integrated fluidic circuits (IFCs), Stanford University researchers to have discovered a much larger spectrum of differences between individual cells than has previously been demonstrated. Among these differences are the communication capabilities that emerge from the interactions of genetic circuitry that mediates cell-to-cell communication.

2 Jul 2010

Shire presents positive data from TKT-025 EXT Phase I/II study for VPRIV in type 1 Gaucher disease patients

Shire plc, the global specialty biopharmaceutical company, today announced positive data from its long-term extension to its open label Phase I/II study (TKT-025 EXT) for VPRIV® (velaglucerase alfa), the company's enzyme replacement therapy for patients with type 1 Gaucher disease. The data were presented at the 9th Annual European Working Group on Gaucher Disease (EWGGD) in Cologne, Germany, and add to the growing body of clinical evidence which supports the safety and sustained efficacy of VPRIV.

2 Jul 2010

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

IBM and the University of Missouri today announced a life sciences research initiative using IBM high performance computing technologies to advance the school's bioinformatics research projects. The goal of the initiative is to develop a first-of-a-kind cloud computing environment for genomics research collaboration at a regional level.

2 Jul 2010

Virus related to hepatitis C discovered in Asian bats

Viral hepatitis affects more than 500 million people worldwide and is a cause of liver failure and liver cancer. While vaccines are available for hepatitis A and B, this is not the case for hepatitis C, which affects as much as two percent of the population in the U.S. Scientists today are reporting discovery of a virus related to hepatitis C in Asian bats, which may provide insights into the origins of the hepatitis C virus and into the mechanisms by which infectious diseases move from other species to humans.

2 Jul 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Children's Hospital Boston researchers reprogram adult blood cells into iPS cells

In findings likely to make it easier and faster for stem cell biologists to generate patient-specific embryonic-like stem cells, researchers at Children's Hospital Boston have reprogrammed adult blood cells into induced pluripotent stem (iPS) cells.

2 Jul 2010

Plant extract effective against ulcerative colitis in mice

A South Dakota State University scientist's research shows an extract made from a food plant in the Brassica family was effective in alleviating signs of ulcerative colitis, an inflammatory bowel condition, in mice.

2 Jul 2010

Frozen blood samples shows promise to study mechanism of blood disorders

Cells from frozen human blood samples can be reprogrammed to an embryonic-stem-cell-like state, according to Whitehead Institute researchers. These cells can be multiplied and used to study the genetic and molecular mechanisms of blood disorders and other diseases.

2 Jul 2010

OTA reminds consumers to choose organic foods over synthetic dye foods

In response to a call from the Center for Science in the Public Interest (CSPI) to ban synthetic dyes to color foods, the Organic Trade Association (OTA) today reminded consumers that they can already avoid such dyes in the marketplace by choosing to purchase organic foods.

2 Jul 2010

BIDMC calls for new training program for personalized healthcare

The Department of Pathology at Beth Israel Deaconess Medical Center (BIDMC) have issued "A Call to Action" for the medical profession to catch up with the technology and business communities in the application of genomics to personalized health care.

2 Jul 2010

Allogeneic stem cell transplant holds promise for treatment-resistant chronic lymphocytic leukemia

Allogeneic (donor-derived) stem cell transplant (alloSCT) may be a promising option for patients with treatment-resistant chronic lymphocytic leukemia (CLL), regardless of the patient's underlying genetic abnormalities, according to the results of a study published online today in Blood, the journal of the American Society of Hematology.

2 Jul 2010

Researchers identify gene abnormality for most common congenital birth defect, clubfoot

Although clubfoot is one of the most common congenital birth defects, few genetic causes have been found. Now, researchers at Washington University School of Medicine in St. Louis have found what they believe to be the most common cause of inherited clubfoot yet discovered.

2 Jul 2010

Cancer stem cells may vary from tumor to tumor, say researchers

Cancer stem cells have enticed scientists because of the potential to provide more durable and widespread cancer cures by identifying and targeting the tumor's most voracious cells.

2 Jul 2010

Genetic News and Research

Transplanted beta cells protect themselves by adapting to their new homes

Web sites that promote anorexia raise concern

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Pennsylvania Department of Health announces new study on blood disorder Polycythemia vera

First US forum gathers doctors and children who no longer need insulin

Eli Lilly, Alnara sign definitive merger agreement

PhenotypeIT launches integrated Corporate Health and Wellness Management Platform

Fluidigm's IFC platform products help perform digital-PCR measurements on single gene

Shire presents positive data from TKT-025 EXT Phase I/II study for VPRIV in type 1 Gaucher disease patients

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

Virus related to hepatitis C discovered in Asian bats

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Children's Hospital Boston researchers reprogram adult blood cells into iPS cells

Plant extract effective against ulcerative colitis in mice

Frozen blood samples shows promise to study mechanism of blood disorders

OTA reminds consumers to choose organic foods over synthetic dye foods

BIDMC calls for new training program for personalized healthcare

Allogeneic stem cell transplant holds promise for treatment-resistant chronic lymphocytic leukemia

Researchers identify gene abnormality for most common congenital birth defect, clubfoot

Cancer stem cells may vary from tumor to tumor, say researchers

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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