DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Broken String Biosciences today announced that its INDUCE-seq™ DNA break-mapping technology had been used in a peer-reviewed research paper to characterize off-target effects of CRISPR-Cas9 gene editing resulting from changes in DNA topology.

From Broken String Biosciences 31 Oct 2023

Promising new drug target for triple-negative breast cancer identified

Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging.

30 Oct 2023

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, seizures, and cognitive disability.

30 Oct 2023

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

A new paper in The Lancet eBioMedicine explores whether these changes predict the future risk of stomach tumors and how epigenetic changes interact with environmental and lifestyle factors in this process.

30 Oct 2023

New bivalent vaccine shows promising results against key fish pathogens

The efficacy of a bivalent vaccine against Aeromonas hydrophila (A. hydrophila) and Streptococcus agalactiae (S. agalactiae).

30 Oct 2023

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Canadian researchers develop a cell-free DNA-based multimodal assay for early cancer detection in patients with Li-Fraumeni Syndrome, a high-cancer-risk condition. The assay outperforms conventional methods, promising more sensitive and less invasive cancer surveillance.

29 Oct 2023

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

27 Oct 2023

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Meet Opentrons at ASHG 2023

Opentrons is a proud exhibitor at ASHG 2023, and we’re excited to be bringing our automation solutions to the conference.

From Opentrons 27 Oct 2023

Study shows phages can promote mammalian cellular growth and survival

Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell.

26 Oct 2023

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

In a Perspective, Stephen Tang and Samuel Sternberg discuss retroelement-based gene editing as a safer alternative to CRISPR-Cas approaches.

26 Oct 2023

Malaria protein discovery opens new avenues for combating deadly infection

The discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite's immune evasion tactics could pave the way for new vaccines or therapeutics to combat the deadly infection.

26 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Study finds link between industry payments to oncologists and non-recommended cancer treatments

Patients with cancer whose oncologist receives payments from industry appear more likely to receive some non-recommended and low value treatments, finds a US study published by The BMJ today.

25 Oct 2023

Boosting brain health with iron and manganese: A dietary defense against cognitive decline

The recent study published in Nutrients explores the link between dietary mineral intake and cognitive impairment in elderly Spanish individuals, finding that increased consumption of iron and manganese significantly reduced cognitive impairment risk in women but showed no effect in men.

25 Oct 2023

Children with genetic predisposition to ASD and ADHD more likely to have longer screen time

A team led by Nagoya University Graduate School of Medicine in Japan has investigated screen time in autistic (ASD) and ADHD children. Screen time refers to the amount of time a person spends on a device with a screen, such as a smartphone, computer, television, or video game system.

25 Oct 2023

Increased homozygosity leads to negative effects on fertility in human population, study finds

When it comes to the architecture of the human genome, it's only a matter of time before harmful genes - genes that could compromise future generations - arise in a population.

25 Oct 2023

DNA News and Research

Further Reading

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

New drug gets FDA approval for the treatment of common genetic disease in young boys

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Promising new drug target for triple-negative breast cancer identified

New MECP2 gene variant identified and characterized in Rett syndrome

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

New bivalent vaccine shows promising results against key fish pathogens

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Novel replacement strategy holds promise for the treatment of various genetic disorders

Meet Opentrons at ASHG 2023

Study shows phages can promote mammalian cellular growth and survival

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

Malaria protein discovery opens new avenues for combating deadly infection

New study challenges long-held belief about how chemotherapy works

Study finds link between industry payments to oncologists and non-recommended cancer treatments

Boosting brain health with iron and manganese: A dietary defense against cognitive decline

Children with genetic predisposition to ASD and ADHD more likely to have longer screen time

Increased homozygosity leads to negative effects on fertility in human population, study finds

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo