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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Wastewater surveillance expanded to detect the presence of monkeypox

An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and which has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.

11 Aug 2022

Transposable element controls the immune system to favor host survival during virus infection

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Scientists discover new target for treatment of premature aging disorders

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology in Saudi Arabia have discovered.

10 Aug 2022

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication.

10 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Review of natural products with promising anti-SARS-CoV-2 potential

In a new study, researchers reviewed existing literature on naturally active products with therapeutic efficacy against SARS-CoV-2.

10 Aug 2022

Experimental drug protects mice from sudden death due to blood vessel rupture

An experimental drug therapy protects mice from sudden death due to the rupture of a major blood vessel in the abdomen, according to a study from researchers at Washington University School of Medicine in St. Louis.

10 Aug 2022

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Researchers monitored the remarkably rapid Omicron BA.1 to BA.2 sublineage dominance transition in the Swedish population in early 2022 on a day-to-day basis using a customized lineage-typing RT-PCR assay.

10 Aug 2022

Coronavirus biology: viral RNA synthesis, origin, and vaccines

Researchers analyzed the characteristics of coronaviruses and novel CoV vaccine candidates.

10 Aug 2022

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Researchers described the development and applications of a 3D-printed lab-on-a-chip device that quickly detected the presence of SARS-CoV-2 in patient's saliva.

10 Aug 2022

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Around 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in them being significantly smaller than the eyes of wild zebrafish.

9 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Research suggests a new nanomedicine strategy for treatment of IBD patients

Inflammatory bowel disease (IBD), also known as "green cancer", is a chronic, non-specific disease of the intestine. IBD includes ulcerative colitis and Crohn's disease, both of which tend to be debilitating, lifelong conditions that can prove fatal in severe cases. Currently, there is no cure for IBD. The main clinical treatments are drugs such as aminosalicylic acid preparations and corticosteroids, but they are often accompanied by gastrointestinal problems, anemia, and various intestinal complications. Finding alternative, more effective options is a priority for researchers.

5 Aug 2022

RNA News and Research

Further Reading

Wastewater surveillance expanded to detect the presence of monkeypox

Transposable element controls the immune system to favor host survival during virus infection

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Scientists discover new target for treatment of premature aging disorders

UTSW scientists discover mechanism of RNA capping by SARS-CoV-2 virus

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Review of natural products with promising anti-SARS-CoV-2 potential

Experimental drug protects mice from sudden death due to blood vessel rupture

A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Coronavirus biology: viral RNA synthesis, origin, and vaccines

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Research progress on the three-dimensional interaction between virus and host genome

New dual-plasmid editing system for DNA-based information rewriting in vivo

Research suggests a new nanomedicine strategy for treatment of IBD patients

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