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LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

AI model accurately predicts lymph node metastasis in nonfunctional pancreatic neuroendocrine tumors

Nonfunctional pancreatic neuroendocrine tumors, while rare, are primarily treated through surgery. The presence or absence of lymph node metastasis considerably influences the selection of surgical and other treatment approaches.

23 Jan 2024

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Coronary heart disease (CHD) and H. Pylori.

23 Jan 2024

Team approach to prostate cancer: PCPs and urologists offer hope with active surveillance

This study considers the perspectives of primary care physicians (PCPs) and urologists on what facilitates and what creates barriers to active surveillance (AS) care for men with low-risk prostate cancer.

22 Jan 2024

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it's hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

22 Jan 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

Receptor protein found to be a key player in prostate cancer cells' drug resistance

Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.

22 Jan 2024

UMass Amherst researcher aims to tackle bone damage in metastatic cancer

For some patients whose cancer has spread to their bones, the ensuing treatment can be more physically damaging than the original disease, leading to increased bone loss and fracture.

22 Jan 2024

Non-destructive cancer grade probing system evaluates malignancy grade of model glioma cells

A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.

22 Jan 2024

Study reveals surprising power of CD4+ T cells against melanoma

In the study led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and published in Science Immunology, the researchers found that CD4+ T cells, traditionally called ‘helper T cells’ for their role in aiding the activation of other immune cells, are remarkably effective in controlling melanoma.

22 Jan 2024

How does social adversity influence biomarkers of stress and inflammation in children?

A recent study assessed whether social adversity affected the biomarkers of inflammation and stress in children.

22 Jan 2024

Immune checkpoint inhibitor target found to promote skin cancer growth

Programmed cell death 1 (PD-1) is an important target for immune checkpoint inhibitor therapies that block its signaling and boost T-cell activity. PD-1 inhibitors have been approved for treating various types of cancer.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

A groundbreaking study conducted by Professor Jiyoung Park and her research team in the Department of Biological Sciences at UNIST has identified FAM3C, a metabolism-regulating signaling molecule produced by cancer-associated adipocytes (CAAs), as a key regulator of breast cancer progression within the tumor microenvironment (TME).

19 Jan 2024

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

Researchers from Miami Cancer Institute, part of Baptist Health South Florida, today published a study in Trends in Cancer that analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors (PBTs).

19 Jan 2024

Evaluating the effectiveness and safety of single-port robot-assisted technique in nipple-sparing mastectomy procedures

Researchers evaluated the safety and feasibility of a single-port (SP) robotic-assisted approach for performing nipple-sparing mastectomies (NSM).

19 Jan 2024

Can yoga improve your prostate health?

The potential benefits of yoga in improving prostate health.

19 Jan 2024

New blood test technique raises hopes for more sensitive and earlier cancer diagnosis

Tumors constantly shed DNA from dying cells, which briefly circulates in the patient's bloodstream before it is quickly broken down. Many companies have created blood tests that can pick out this tumor DNA, potentially helping doctors diagnose or monitor cancer or choose a treatment.

18 Jan 2024

Machine learning algorithm decodes mutations driving cancer treatment resistance

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, scientists at University of California San Diego School of Medicine leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy.

18 Jan 2024

Tumor News and Research

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

AI model accurately predicts lymph node metastasis in nonfunctional pancreatic neuroendocrine tumors

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Team approach to prostate cancer: PCPs and urologists offer hope with active surveillance

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

Cancer drug holds promise for shrinking polycystic kidney cysts

Receptor protein found to be a key player in prostate cancer cells' drug resistance

UMass Amherst researcher aims to tackle bone damage in metastatic cancer

Non-destructive cancer grade probing system evaluates malignancy grade of model glioma cells

Study reveals surprising power of CD4+ T cells against melanoma

How does social adversity influence biomarkers of stress and inflammation in children?

Immune checkpoint inhibitor target found to promote skin cancer growth

Ludwig scientists deconstruct the blood supply of brain metastases

Annexin-A1 targeted therapy beats several cancers

Groundbreaking study identifies FAM3C as a key regulator of breast cancer progression

Study analyzes the use of tissue-agnostic therapeutics in patients with primary brain tumors

Evaluating the effectiveness and safety of single-port robot-assisted technique in nipple-sparing mastectomy procedures

Can yoga improve your prostate health?

New blood test technique raises hopes for more sensitive and earlier cancer diagnosis

Machine learning algorithm decodes mutations driving cancer treatment resistance

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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