Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

New study reveals oral opaganib's potent in vitro activity against Omicron

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced study results in which opaganib (ABC294640), a leading oral drug candidate for hospitalized patients with moderate to severe COVID-19, was observed to have potent in vitro efficacy against the Omicron SARS-CoV-2 variant, while maintaining host cell viability.

11 Apr 2022

Study finds higher risk of all-cause mortality among pediatric cancer patients in LMICs during the pandemic

During the first nine months of the COVID-19 pandemic, pediatric cancer patients from lower- and middle-income countries faced a higher risk of all-cause mortality than those in high-income countries, according to data presented at the AACR Annual Meeting 2022, held April 8-13.

11 Apr 2022

New instrument will help Columbia scientists to study heavy ion radiation therapy

Heavy ions could radically improve radiation therapy for treatment of pancreatic cancer and other difficult-to-treat tumors if researchers can better understand how the ions work against cancer.

11 Apr 2022

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Adding the immunotherapy drug nivolumab to chemotherapy before surgery (neoadjuvant) for patients with operable non-small cell lung cancer (NSCLC) — the leading cause of cancer deaths worldwide — reduced the risk of recurrence of the cancer or death by more than one-third, according to results from the phase III CheckMate-816 trial.

11 Apr 2022

Study: Less than half of clinical trials report race/ethnicity data

Clinical trials represent one the largest investments of collective resources in science. These studies, which recruit participants and rigorously evaluate new interventions and therapeutics, aim to advance scientific knowledge and improve patient treatment.

11 Apr 2022

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Patients with non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitor sotorasib (Lumakras) had a two-year overall survival rate of 32.5 percent, according to data from the CodeBreaK 100 clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Novel therapy advances to clinical trial for the treatment of glioblastoma

A novel therapy studied at the Medical College of Wisconsin (MCW) Cancer Center has led to a clinical trial for the treatment of glioblastoma, a rare and aggressive form of brain cancer, yet the most common primary brain tumor in adults.

10 Apr 2022

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

A new study led by Susan G. Komen® Scholars indicates that patients diagnosed with de novo stage 4 breast cancer – also called metastatic breast cancer– had improved survival rates and decreased mortality rates when those patients had access to care.

10 Apr 2022

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Radiation to the heart during treatment for locally advanced lung cancer is associated with an increased risk of major adverse cardiac events within the first two years following treatment. The higher the cardiac dose exposure, the higher the risk of a cardiac event.

8 Apr 2022

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors are often switched to treatment with a second type of immunotherapy drug – a CTLA-4 inhibitor such as the drug ipilimumab.

8 Apr 2022

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Most autoimmune diseases are easy to diagnose but hard to treat. A paper published today in Science proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.

7 Apr 2022

New website offers accurate, reliable information about causes of cancer

A team led by the Zhu Family Center for Global Cancer Prevention at Harvard T.H. Chan School of Public Health and the Center for Cancer Equity and Engagement at the Dana-Farber/Harvard Cancer Center has launched Cancer FactFinder (https://cancerfactfinder.org/), a new website that provides accurate and reliable information about what does and does not cause cancer.

7 Apr 2022

Creation of immunosuppressive environment is key to the progression of colorectal cancer development

Interactions between cells of the immune system and pre-cancerous cells are known to be important contributing factors to the initiation and progression of cancer.

7 Apr 2022

Study captures the immune effect of COVID-19 vaccine in patients with multiple myeloma

Most immunocompromised people with a blood cancer called multiple myeloma benefited from a third dose of COVID-19 vaccines, a promising sign after it was shown that two doses tended to not be sufficient for them.

6 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

In the presence of pancreatic tumors, certain immune cells break down structural proteins into molecules that trigger the building of dense tissue, a known barrier to therapy, a new study finds.

4 Apr 2022

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.

4 Apr 2022

$2.05 million to support UTHSC's advanced genetics project on breast cancer

A University of Tennessee Health Science Center team has received $2.05 million from the National Cancer Institute for an advanced genetics project that could help develop targeted therapies and personalized treatment for breast cancer. Liza Makowski, PhD, professor of Hematology and Oncology in the College of Medicine, is the lead investigator on the award.

31 Mar 2022

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

An analysis by Yale Cancer Center researchers identified accelerated genetic aging in breast tissue adjacent to breast cancer tumors.

31 Mar 2022

Oncology News and Research

Further Reading

New study reveals oral opaganib's potent in vitro activity against Omicron

Study finds higher risk of all-cause mortality among pediatric cancer patients in LMICs during the pandemic

New instrument will help Columbia scientists to study heavy ion radiation therapy

Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Study: Less than half of clinical trials report race/ethnicity data

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Novel therapy advances to clinical trial for the treatment of glioblastoma

Study shows benefits of Medicaid expansion for patients diagnosed with de novo stage 4 breast cancer

Simple interventions reduced radiation exposure to the heart during lung cancer treatment

Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

New website offers accurate, reliable information about causes of cancer

Creation of immunosuppressive environment is key to the progression of colorectal cancer development

Study captures the immune effect of COVID-19 vaccine in patients with multiple myeloma

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

$2.05 million to support UTHSC's advanced genetics project on breast cancer

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

Industry Focus eBook - Oncology (3rd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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