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Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

In a recent study posted to the Research Square* preprint server, researchers tested the safety and immunogenicity of a third dose of coronavirus disease 2019 (COVID-19) prototype messenger ribonucleic acid (mRNA)-1273 versus a variant vaccine and a bivalent vaccine formulation.

5 May 2022

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

A recent study posted to the bioRxiv* preprint server demonstrated that the latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages evade immunity imparted by the prior subvariants.

5 May 2022

New study helps explain the immune system’s response to skin infections and skin cancers

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response.

4 May 2022

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines

Scientists have discussed the possibilities of developing oral replicon-based mRNA vaccines against SARS-CoV-2.

4 May 2022

The war against COVID-19: reinfection, vaccines, and herd immunity

A communication published in the journal Epidemiologia aimed to answer several questions concerning neutralizing antibodies against SARS-CoV-2, herd immunity, and COVID-19 vaccines.

4 May 2022

The extent to which COVID-19 vaccination rates and vaccine hesitancy are associated with levels of online vaccine misinformation

A new study has determined the link between vaccine hesitancy, vaccination rates, and online misinformation across the US.

4 May 2022

The effectiveness of shielding strategies for COVID-19

Researchers have used a mathematical model to assess if shielding the most vulnerable group while allowing infection to transmit through low-risk groups is an effective policy to combat the COVID-19 pandemic

4 May 2022

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

The current study aimed to understand how far this reduced vaccine efficacy and the protection conferred by prior infection in terms of Omicron infection, hospitalization, and oxygen supplementation.

4 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022

Injectable hydrogels for single-dose COVID-19 vaccination

Several coronavirus disease 2019 (COVID-19) vaccines require multiple doses for long-lasting immunity. However, a new study published in the journal Biomacromolecules has developed a promising single-dose vaccine platform using an injectable hydrogel containing an epitope-labeled plant virus, Cowpea mosaic virus (CPMV).

4 May 2022

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

In a recent study published in the journal Cell, researchers investigated distinguishing virological characteristics of Omicron sub-variant BA.2.

3 May 2022

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

A recent study under review at Nature Portfolio and posted to the Research Square* preprint server depicted how cellular nucleic acid-binding protein (CNBP) inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

In a new study, a worldwide map of the SARS-CoV-2 genome-associated host proteins was developed by a team of researchers using the identification of RNA-binding protein by MS (ChIRP-MS) technique.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

A new study analyzed multivalent messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine constructs against certain β-coronaviruses (β-CoVs).

3 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

Study reveals Omicron sub-lineages BA.4 and BA.5 escape neutralizing antibodies elicited in response to BA.1 infection

Researchers evaluated whether neutralizing immunity elicited against Omicron sub-variant BA.1 in unvaccinated and vaccinated individuals adequately protected against infection by Omicron sub-variants, BA.4 and BA.5.

3 May 2022

Features of SARS-CoV-2 Omicron BA.2 sublineage spike protein

Researchers assessed the traits of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 sublineage spike (S) protein.

3 May 2022

Study suggests aerosol transmission of antibodies may contribute to host protection against SARS-CoV-2

A new study has addressed the previously mentioned research gap and has investigated the possibility of transfer of aerosol containing SARS-CoV-2-specific antibodies between vaccinated and non-immune hosts

3 May 2022

Schools' role in the spread of SARS-CoV-2

The Omicron wave of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)––the causative pathogen for coronavirus disease 2019 (COVID-19) and the current pandemic––led to rampant transmissions in schools. Therefore, the school-based viral transmission must be curtailed to reduce viral evolution and maintain children's in-person education.

2 May 2022

immunity News and Research

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

New study helps explain the immune system’s response to skin infections and skin cancers

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines

The war against COVID-19: reinfection, vaccines, and herd immunity

The extent to which COVID-19 vaccination rates and vaccine hesitancy are associated with levels of online vaccine misinformation

The effectiveness of shielding strategies for COVID-19

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

Researchers reveal the mechanism of action of century-old BCG vaccine

Injectable hydrogels for single-dose COVID-19 vaccination

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Study explores SARS-CoV-2 RNA genome's functional interactions with host cell

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Study reveals Omicron sub-lineages BA.4 and BA.5 escape neutralizing antibodies elicited in response to BA.1 infection

Features of SARS-CoV-2 Omicron BA.2 sublineage spike protein

Study suggests aerosol transmission of antibodies may contribute to host protection against SARS-CoV-2

Schools' role in the spread of SARS-CoV-2

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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