Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

New DNA test can predict adult heart attack risk much earlier in life

People at high risk of a heart attack in adulthood could be spotted much earlier in life with a one-off DNA test, according to new research part-funded by the British Heart Foundation and published today in the Journal of the American College of Cardiology.

9 Oct 2018

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

Inflammation is currently a well-documented component of atheroslcerosis pathogenesis, which plays a role at each stage of the disease development.

6 Oct 2018

Yo-yo dieting increases risk of heart attack and stroke, finds study

In the study, sudden changes in metabolic health parameters were associated with a raised risk of heart attacks, strokes and even early deaths.

4 Oct 2018

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

Over half of all breast cancers carry genetic defects in the p53 gene, a powerful tumor suppressor. Loss of this gene increases the risk of getting breast cancer and the resultant cancers become highly resistant to treatment.

4 Oct 2018

Liver transplant and weight-loss surgery combination offers long-term benefits to obese patients

Obese patients who underwent a life-saving liver transplant and weight-loss surgery at the same time were better able to keep the weight off long term and had fewer metabolic complications than those who lost weight on their own before undergoing a liver transplant, Mayo Clinic research shows.

3 Oct 2018

New tool provides improved in vivo imaging of atherosclerotic plaque development

Atherosclerosis, involving the buildup of plaque in the arteries and an associated reduction in the flow of blood, is a major feature of cardiovascular diseases.

28 Sep 2018

High levels of fibroblast growth factor 23 may affect brain health

Scientists at the Medical University of South Carolina have uncovered mechanisms by which high levels of a hormone called FGF23 can reduce brain health.

28 Sep 2018

Genetic score helps predict future major coronary events, shows study

Coronary artery disease (CAD) is the leading killer of people with type 2 diabetes, and it's not a secret killer.

28 Sep 2018

Diet comprising of soups and shakes may combat obesity

According to a new study a diet comprising of soups and shakes replacing regular food could help people with obesity to lose weight significantly and sustain it over time.

27 Sep 2018

Study explores link between genetic predisposition to Alzheimer's and cardiometabolic risk factors

Alzheimer's disease is the most common memory disorder. In addition to genetic predisposition, the risk of Alzheimer's disease is also increased by cardiometabolic risk factors, such as type 2 diabetes. The accumulation of these risk factors is known as the metabolic syndrome.

25 Sep 2018

Harmful H. pylori may play a role in Parkinson's disease

While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental causes, prompting enormous interest in identifying environmental risk factors involved.

25 Sep 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

Blood, sweat and workplace wellness: Where to draw the line on incentives

Workplace wellness programs that offer employees a financial carrot for undergoing health screenings, sticking to exercise regimens or improving their cholesterol levels have long been controversial.

24 Sep 2018

Rural borderland communities vulnerable to high stress impacting mental and physical health

The borderlands between the United States and Mexico are home to numerous Mexican and Central American rural communities, with many members living in poverty and frustrated by limited access to basic resources.

21 Sep 2018

Body organs undergo structural changes in response to diet

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie's Rebecca Obniski, Matthew Sieber, and Allan Spradling.

20 Sep 2018

Celltrion and Emory University sign 'Incubation' agreement to develop new drug candidates for atherosclerosis

Celltrion, Inc. signed an 'Incubation' agreement with Emory University in Atlanta to support the research and development of new drug candidates for atherosclerosis.

20 Sep 2018

The use of aspirin in elderly now questioned

A large study led by Australian researchers has found that taking Aspirin tablets regularly to does not really prolong life or reduce the risk of a first heart attack or stroke.

16 Sep 2018

Study shows cost-effectiveness of financial incentive program to control cholesterol

A program that offered financial incentives to both patients and their physicians to control low-density lipoproteins cholesterol could be a cost-effective intervention for patients at high risk of cardiovascular disease, according to new research led by Harvard T.H. Chan School of Public Health.

14 Sep 2018

'Nudges' may help curb decline in influenza vaccination rates as the day progresses

Primary care clinics experienced a significant decline in influenza vaccinations as the day progressed, researchers from Penn Medicine report in a new study published in JAMA Open Network.

14 Sep 2018

Cholesterol News and Research

Further Reading

New DNA test can predict adult heart attack risk much earlier in life

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

Yo-yo dieting increases risk of heart attack and stroke, finds study

Blocking stress-responsive protein reduces loss of tumor suppressor gene in breast cancer

Liver transplant and weight-loss surgery combination offers long-term benefits to obese patients

New tool provides improved in vivo imaging of atherosclerotic plaque development

High levels of fibroblast growth factor 23 may affect brain health

Genetic score helps predict future major coronary events, shows study

Diet comprising of soups and shakes may combat obesity

Study explores link between genetic predisposition to Alzheimer's and cardiometabolic risk factors

Harmful H. pylori may play a role in Parkinson's disease

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

Blood, sweat and workplace wellness: Where to draw the line on incentives

Rural borderland communities vulnerable to high stress impacting mental and physical health

Body organs undergo structural changes in response to diet

Celltrion and Emory University sign 'Incubation' agreement to develop new drug candidates for atherosclerosis

The use of aspirin in elderly now questioned

Study shows cost-effectiveness of financial incentive program to control cholesterol

'Nudges' may help curb decline in influenza vaccination rates as the day progresses

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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