Clinical Trial News and Research

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First-in-human clinical trial of liver dialysis device successfully completed

The first successful in-patient trial of liver dialysis* has been completed by researchers from UCL, the Royal Free Hospital, UCL spin-out Yaqrit and their collaborators.

31 May 2023

Breast cancer patients experience more severe CIPN symptoms with paclitaxel

Chemotherapy-induced peripheral neuropathy (CIPN) – nerve pain, tingling, or numbness in the hands or feet – is a common side effect of certain cancer treatments, including two drugs frequently used to treat cancer – the taxanes paclitaxel and docetaxel.

31 May 2023

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

An international team, led by UBC Okanagan researchers, suggests a simple tweak to the first meal of the day might help people living with Type 2 diabetes (T2D) better control their blood sugar levels.

31 May 2023

Extended lymphadenectomy for locally advanced bladder cancer provides no patient benefit

An extended lymphadenectomy – removal of additional lymph nodes beyond the extent of the standard procedure – in patients undergoing radical cystectomy (removal of bladder and nearby tissues) because of clinically localized muscle-invasive bladder cancer provides no patient benefit as measured by disease-free survival or overall survival times.

30 May 2023

Treatment with modified lactic acid bacteria accelerates the healing of wounds, study shows

Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy.

30 May 2023

Unhealthy diet results in shallower deep sleep

In a new study, researchers at Uppsala University have investigated how junk food affects sleep. Healthy participants consumed an unhealthier as well as a healthier diet in a randomized order.

30 May 2023

Precision nutrition vs. low-fat diet: No significant difference in diabetes management

Researchers compare changes in hemoglobin A1c and glycemic variability to understand the impacts of two calorie-restricted weight loss diets.

30 May 2023

Memory boost with multivitamins: Study reveals improved cognitive function in older adults

Researchers investigate whether one year of supplementation with multivitamins could improve hippocampus-mediated cognition and memory in older adults.

29 May 2023

Diet low in flavanols linked to age-related memory loss

A large-scale study led by researchers at Columbia and Brigham and Women's Hospital/Harvard is the first to establish that a diet low in flavanols - nutrients found in certain fruits and vegetables - drives age-related memory loss.

29 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Telephone-based weight loss program can help patients with breast cancer to reduce their weight

Women with obesity when they are diagnosed with early breast cancer have a higher risk of recurrence or a second cancer compared to women whose weight is in the normal range and it can be hard to lose weight after being diagnosed with breast cancer.

26 May 2023

New treatment protocol for brain hemorrhage improves survival chances without major disability

The George Institute for Global Health today announced data from the phase III INTERACT3 study demonstrating that a new combination of treatments for stroke due to intracerebral hemorrhage (ICH) significantly improves the chances of surviving without major disability.

26 May 2023

$4.5 million grant to fund research exploring link between exercise and slowing Alzheimer's progression

A $4.5 million groundbreaking grant will fund research to explore a promising link between aerobic exercise and slowing the progression of Alzheimer's disease in a study led by an Arizona State University researcher.

26 May 2023

Do glucose-lowering medications have different effects on kidney outcomes?

Researchers evaluated the kidney outcomes in individuals with type 2 diabetes.

26 May 2023

A groundbreaking digital brain–spine bridge empowers tetraplegic patient to walk naturally after spinal cord injury

Researchers developed a groundbreaking wireless digital bridge that helped a chronic tetraplegia patient to walk.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

UTHealth Houston receives federal funding for traumatic brain injury research

Nearly $13 million in federal grant funds to study treatments for traumatic brain injury, which kills an average of 190 people and hospitalizes another 600 in the U.S. every day, has been awarded to UTHealth Houston by the Department of Defense's Office of Congressionally Directed Medical Research Programs (CDMRP).

25 May 2023

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

25 May 2023

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Swansea University researchers have found that a drug commonly used to treat type 2 diabetes can potentially be used in the treatment of autoimmune disorders.

25 May 2023

Examining first treatment for strokes linked to dementia

People who experience a type of stroke linked with nearly half of all dementias could be treated for the first time by repurposing two cheap and common drugs, a trial shows.

25 May 2023

Clinical Trial News and Research

First-in-human clinical trial of liver dialysis device successfully completed

Breast cancer patients experience more severe CIPN symptoms with paclitaxel

A simple tweak to first meal of the day may benefit people with Type 2 diabetes

Extended lymphadenectomy for locally advanced bladder cancer provides no patient benefit

Treatment with modified lactic acid bacteria accelerates the healing of wounds, study shows

Unhealthy diet results in shallower deep sleep

Precision nutrition vs. low-fat diet: No significant difference in diabetes management

Memory boost with multivitamins: Study reveals improved cognitive function in older adults

Diet low in flavanols linked to age-related memory loss

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Telephone-based weight loss program can help patients with breast cancer to reduce their weight

New treatment protocol for brain hemorrhage improves survival chances without major disability

$4.5 million grant to fund research exploring link between exercise and slowing Alzheimer's progression

Do glucose-lowering medications have different effects on kidney outcomes?

A groundbreaking digital brain–spine bridge empowers tetraplegic patient to walk naturally after spinal cord injury

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

UTHealth Houston receives federal funding for traumatic brain injury research

First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

Common diabetes drug could be repurposed as a treatment for autoimmune disorders

Examining first treatment for strokes linked to dementia

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