Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Further Reading

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

16 Jan 2013
Thermo Fisher's expandable portfolio of lab automation solutions to be showcased at SLAS 2013

Thermo Fisher's expandable portfolio of lab automation solutions to be showcased at SLAS 2013

From Thermo Fisher Scientific Inc. 16 Jan 2013
UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

11 Jan 2013
Pfizer, Repligen sign licensing deal to advance spinal muscular atrophy program

Pfizer, Repligen sign licensing deal to advance spinal muscular atrophy program

3 Jan 2013
Kareus announces start of KU-046 Phase I study in Alzheimer's

Kareus announces start of KU-046 Phase I study in Alzheimer's

3 Jan 2013
Vismodegib team wins Drug Discovery of the Year award

Vismodegib team wins Drug Discovery of the Year award

19 Dec 2012
British Pharmacological Society celebrates the start of annual meeting

British Pharmacological Society celebrates the start of annual meeting

19 Dec 2012
Fluidigm, GIS announce establishment of first single-cell genomics research center in Asia

Fluidigm, GIS announce establishment of first single-cell genomics research center in Asia

15 Dec 2012
New way to effectively make designer drugs that hit collections of protein targets simultaneously

New way to effectively make designer drugs that hit collections of protein targets simultaneously

13 Dec 2012
New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

New collaborative model for drug discovery can ensure antibiotics are not lost to resistance

12 Dec 2012
GSK, Fred Hutch to develop therapeutics against facioscapulohumeral muscular dystrophy

GSK, Fred Hutch to develop therapeutics against facioscapulohumeral muscular dystrophy

11 Dec 2012
Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

11 Dec 2012
Isis, Biogen Idec partner to discover and develop antisense drugs against neuromuscular disorders

Isis, Biogen Idec partner to discover and develop antisense drugs against neuromuscular disorders

11 Dec 2012
New study could help develop anti-inflammatory drugs with fewer side effects

New study could help develop anti-inflammatory drugs with fewer side effects

10 Dec 2012
Bicycle Therapeutics secures £3.75 million equity financing for drug discovery

Bicycle Therapeutics secures £3.75 million equity financing for drug discovery

10 Dec 2012
Scientists identify key molecular pathway that leads to depression

Scientists identify key molecular pathway that leads to depression

6 Dec 2012
USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

5 Dec 2012
Primitive human stem cells resistant to human cytomegalovirus

Primitive human stem cells resistant to human cytomegalovirus

30 Nov 2012
Two Sanford-Burnham projects win International Space Station Research Competition

Two Sanford-Burnham projects win International Space Station Research Competition

30 Nov 2012
Researchers discover alternative mechanism for Ras protein activation

Researchers discover alternative mechanism for Ras protein activation

28 Nov 2012

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