Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Research provides new insights into molecular basis of X-chromosome inactivation

Researchers at the European Molecular Biology Laboratory in Heidelberg and Institut Curie in Paris have shown that the protein SPEN plays a crucial role in the process of X-chromosome inactivation, whereby female mammalian embryos silence gene expression on one of their two X chromosomes.

7 Feb 2020

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

Breastfeeding women with a pathogenic BRCA1 or BRCA2 genetic mutation face a significant risk, even at a young age, of breast and ovarian cancer.

6 Feb 2020

Researchers discover new genetic drivers of cancer

The discovery of genetic drivers of cancer can have critical implications for the diagnosis and treatment of cancer patients, yet genome analysis has focused primarily on only 1-2% of the whole genome - the part that contains the code for making proteins.

5 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020

Novel approach may offer a more effective way to eradicate colorectal cancer cells

A novel approach to reverse the progression of healthy cells to malignant ones may offer a more effective way to eradicate colorectal cancer cells with far fewer side effects, according to a team of researchers based in South Korea.

3 Feb 2020

Sperm microbiome revealed with RNA sequencing

A new study reports the first-ever detailed description of the human sperm microbiome, using newer RNA sequencing techniques that are capable of discriminating between sperm RNA and that of bacterial contamination or colonization.

2 Feb 2020

First in-depth analysis of primate ovarian aging at single-cell resolution

Due to the modern tendency to postpone childbirth until later in life, a growing number of women are experiencing issues with infertility.

30 Jan 2020

Researchers use new technique to improve the ability to model lung diseases

Using a combination of pluripotent stem cells (cells that can potentially produce any cell or tissue type) and machine learning (artificial intelligence that allows computers to learn automatically), researchers have improved how they generate lung cells.

30 Jan 2020

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

Typical examples include paralysis due to a spinal cord injury and visual field atrophy or even complete blindness due to optic nerve atrophy in glaucoma patients.

30 Jan 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

The study reveals a detailed epigenetic mechanism for how interleukin-1-beta, a common cytokine that helps fight infections during inflammation, plays a critical role in cancer metastasis.

29 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

Hokkaido University scientists reveal missing link in rare inherited skin disease

Hokkaido University scientists are getting closer to understanding how a rare hereditary disease impairs the skin's barrier function, which determines how well the skin is protected.

29 Jan 2020

New AI tool predicts disease progression and evolution in neurodegenerative disorders

Researchers have found that testing blood using an artificial intelligence algorithm successfully predicted disease progression in neurodegenerative disorders.

28 Jan 2020

AI analysis of blood samples can predict progression of neurodegenerative disease

Evaluating the effectiveness of therapies for neurodegenerative diseases is often difficult because each patient's progression is different.

28 Jan 2020

Study finds unexpected response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles.

28 Jan 2020

Algae improves human gastrointestinal issues, study shows

A widespread, fast-growing plant called Chlamydomonas reinhardtii is famous in scientific laboratories due to its position as the world's most exhaustively studied algae.

27 Jan 2020

A single number aids biomedical data scientists in finding deadly cancer cells

Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could make it easier to target cancer-causing genes.

24 Jan 2020

Researchers observe fast and slow molecular pathways that support memory function

A sustained state of vigilance will generate a different type of memory than a momentary startle, and these differences are linked to distinct signaling molecules in the brains of mice.

24 Jan 2020

Transcriptional scanning in the sperm may regulate rate of human evolution

Maturing sperm cells turn on most of their genes, not to follow their genetic instructions like normal, but instead to repair DNA before passing it to the next generation, a new study finds.

23 Jan 2020

Gene Expression News and Research

Further Reading

Research provides new insights into molecular basis of X-chromosome inactivation

UMass Amherst study aims to develop new test for BRCA-positive lactating moms

Researchers discover new genetic drivers of cancer

Making it all work: brain-dependent immune activation in embryos

Novel approach may offer a more effective way to eradicate colorectal cancer cells

Sperm microbiome revealed with RNA sequencing

First in-depth analysis of primate ovarian aging at single-cell resolution

Researchers use new technique to improve the ability to model lung diseases

Regulating neuronal lipid metabolism helps axon regeneration after injury, study finds

Researchers discover new target for repairing heart after heart attack

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

Pre-existing anticancer drug could help treat common form of heart failure

Hokkaido University scientists reveal missing link in rare inherited skin disease

New AI tool predicts disease progression and evolution in neurodegenerative disorders

AI analysis of blood samples can predict progression of neurodegenerative disease

Study finds unexpected response to estrogen at the single cell level

Algae improves human gastrointestinal issues, study shows

A single number aids biomedical data scientists in finding deadly cancer cells

Researchers observe fast and slow molecular pathways that support memory function

Transcriptional scanning in the sperm may regulate rate of human evolution

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy