Fluorescence News and Research

RSS

New cell analysis platform developed - commercial partners sought

Sandia National Laboratories is seeking commercial partners to license or contribute to the continued development of a new lab-on-a-chip platform for high-throughput manipulation and interrogation of individual cells, one that enables quantitative analysis of cellular behaviors with unprecedented speed, resolution, sensitivity, and multiplexing.

1 Dec 2008

Potential gene target for treatment of common hearing, vertigo and balance problems

A UCLA study shows for the first time how microscopic crystals form sound and gravity sensors inside the inner ear.

30 Nov 2008

Condensin II proteins found to keep chromosomes apart when necessary

If chromosomes snuggle up too closely at the wrong times, the results can be genetic disaster.

28 Nov 2008

How microscopy can unlock the key to disease

A leading international scientist will reveal how the latest techniques in microscopy - including time-lapse imaging of living cells - are leading to breakthroughs in understanding genetic and acquired diseases.

26 Nov 2008

Scientists develop 'barcode chip' to revolutionize diagnostic medical testing

In less than 10 minutes, and using just a pinprick's worth of blood, the chip can measure the concentrations of dozens of proteins, including those that herald the presence of diseases like cancer and heart disease.

25 Nov 2008

Carbon nanotubes improve protein array detection limits

To detect cancer as early as possible, dozens of research groups are developing methods to detect trace levels of cancer-related proteins and genes in blood or other biological samples.

20 Nov 2008

Researchers identify best time for stem cell collection for Parkinson's therapy

Researchers have identified a stage during dopamine neuron differentiation that may be an ideal time to collect human embryonic stem cells for transplantation to treat Parkinson's disease, according to data presented at Neuroscience 2008, the 38th annual meeting of the Society for Neuroscience.

19 Nov 2008

Researchers define ideal time for stem cell collection for Parkinson's disease therapy

19 Nov 2008

Biomedical research could benefit from deep sea

A study published in the scientific journal PLoS ONE highlights how the exploration of the ocean depths can benefit humankind.

19 Nov 2008

Nontoxic nanoparticle delivers and tracks drugs

A nontoxic nanoparticle developed by Penn State researchers is proving to be an all-around effective delivery system for both therapeutic drugs and the fluorescent dyes that can track their delivery.

18 Nov 2008

Scientists discover new cause of fatal brain injury from acute viral meningitis

In a November 16 advance, online publication of the journal Nature, the researchers say their discovery revamps common beliefs about how such potentially lethal infections may be ravaging the brain and suggests the possibility of new treatments.

17 Nov 2008

Microarray analysis improves prenatal diagnosis

A "chip" or array that can quickly detect disorders such as Down syndrome or other diseases associated with chromosomal abnormalities proved an effective tool in prenatal diagnosis in a series of 300 cases at Baylor College of Medicine, said researchers in a report that appears in the current issue of the journal Prenatal Diagnosis.

17 Nov 2008

Breakthrough in cellular analysis

Like skilled assassins, many diseases seem to know exactly what types of cells to attack.

16 Nov 2008

Breakthrough in cell-type analysis offers new ways to study development and disease

Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable or not depends largely on the kinds and amounts of proteins they produce - their 'translational profile,' in the lingo of molecular biology. For this reason, scientists have struggled to parse the subtle molecular differences among the hundreds of specialized cell types that are tangled together in tissues like the brain.

13 Nov 2008

Researchers uncover beneficial mechanism of the helpful "Dr. Jekyll" side of the Cdk5 protein

Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage.

12 Nov 2008

Protein can nurture or devastate brain cells, depending on its 'friends,' UT Southwestern researchers find

11 Nov 2008

Visualizing asthma-causing immune cells at work

Immune cells known as eosinophils have a central role in causing asthma.

7 Nov 2008

Researchers screen 700 molecules by RNAi to identify host factors involved in malaria infection

The researchers of the Malaria Unit at Instituto de Medicina Molecular (IMM, Lisbon, Portugal) publish in the peer reviewed journal PLoS Pathogens the results of a large scale screening of more than 700 genes to identify host factors involved in the liver stage of malaria infection.

7 Nov 2008

Brain development takes an unexpected bend

Organs, such as the brain or the heart, are not simply collections of the correct types of cells that are required for their function. If these cells are not organized and shaped properly, the organ simply does not function. One crucial part of this organization is to bend sheets of connected cells ("epithelia") so that they form a structure that is an integral part of the functional organ.

4 Nov 2008

Scientists step closer to finding a defense against superbugs

A discovery from the Oklahoma Medical Research Foundation has put scientists are one step closer to finding a defense against dangerous antibiotic-resistant bacteria, sometimes called "superbugs."

4 Nov 2008