Preclinical News and Research

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Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

A unique two-drug immunotherapy combination first evaluated at Roswell Park Comprehensive Cancer Center as an approach for treating some cancers will soon be available to cancer patients with COVID-19 through a clinical trial at Roswell Park.

12 May 2020

Sanford director receives major grant to advance broad-spectrum antivirals for respiratory diseases

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce that Sumit Chanda, Ph.D., has received a $10.2 million, four-year grant from the Department of Defense to develop and advance broad-spectrum antivirals for respiratory diseases.

12 May 2020

COVID-19 patients improve after experimental heart cell therapy

Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this disease, according to a case series published by Cedars-Sinai and Capricor Therapeutics.

12 May 2020

Study: New combination treatment significantly improves degenerative joint diseases

Hutchinson-Gilford Progeria Syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure.

12 May 2020

New two-in-one shot could make it easier for diabetics to control their blood sugar

A Stanford research team has developed a way to boost the effectiveness of the insulin injections people with diabetes routinely take to control their blood sugar.

11 May 2020

Indiana researchers identify new target for colorectal cancer immunotherapy

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy.

11 May 2020

Predictive models could more accurately detect early-stage Parkinson's disease

How is your sense of smell? Do you find yourself frequently dozing off during the day or thrashing about during dreams? Often, early stage Parkinson's disease does not present with typical motor disturbance symptoms, making diagnosis problematic.

11 May 2020

Breakthrough study could revolutionize cancer treatment

Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease.

10 May 2020

Low-molecular-weight drugs could help against COVID-19 says study

Chinese researchers have worked on using existing low molecular weight drugs to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

10 May 2020

Texas A&M study offers hope for young children diagnosed with Menkes disease

A Texas A&M AgriLife Research team has good news for patients with copper-deficiency disorders, especially young children diagnosed with Menkes disease.

9 May 2020

The nutritional key to control autoimmunity and cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

8 May 2020

Novel anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

8 May 2020

Moderate physical activity reduces frequent hospital admissions in middle and older age

Men and women aged 40-79 are at significantly lower (25-27%) risk of long or frequent hospital admissions if they do some form of physical activity, a new study suggests.

7 May 2020

Twist Bioscience Identifies Competitive Antibodies for SARS-CoV-2

Twist Bioscience Corporation has identified competitive antibodies to SARS-CoV-2, which could potentially be used for diagnostic tests and treatments.

7 May 2020

BIOCAD becomes Vector’s industrial partner to develop COVID-19 vaccine

The biotechnology company BIOCAD has signed an agreement with the State Scientific Center for Virology and Biotechnology &laquoVektor» (Novosibirsk) on joint work on a vaccine based on rVSV against the COVID-19 virus.

7 May 2020

New preclinical study shows promise for treating necrotizing enterocolitis

Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients.

6 May 2020

Activation of estrogen receptor can impede growth of pancreatic cancer cells

Activating the G protein-coupled estrogen receptor - a receptor found on the surface of many normal and cancer tissues - has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy.

4 May 2020

FDA approves SFU professor's invention to wean COVID-19 patients from ventilators

Simon Fraser University professor Andy Hoffer hopes the SFU spinoff company he founded, Lungpacer Medical Inc., will help save the lives of COVID-19 patients using mechanical ventilators--and get them off more quickly, so that more ventilators can be available for all critically ill patients.

4 May 2020

Researchers examine role of immune response in COVID-19 patients

A new USC study suggests that temporarily suppressing the body's immune system during the early stages of COVID-19 could help a patient avoid severe symptoms.

4 May 2020

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

A new study shows that the initially lauded combination of drugs against COVID-19 - Hydroxychloroquine and Chloroquine combined with azithromycin, could lead to abnormal and life-threatening heart rhythms. In patients hospitalized with the novel coronavirus infection or SARS CoV-2, this combination can lead to prolonged QT interval as can be detected on ECG.

3 May 2020

Preclinical News and Research

Clinical trial to evaluate two-drug immunotherapy combination in cancer patients with COVID-19

Sanford director receives major grant to advance broad-spectrum antivirals for respiratory diseases

COVID-19 patients improve after experimental heart cell therapy

Study: New combination treatment significantly improves degenerative joint diseases

New two-in-one shot could make it easier for diabetics to control their blood sugar

Indiana researchers identify new target for colorectal cancer immunotherapy

Predictive models could more accurately detect early-stage Parkinson's disease

Breakthrough study could revolutionize cancer treatment

Low-molecular-weight drugs could help against COVID-19 says study

Texas A&M study offers hope for young children diagnosed with Menkes disease

The nutritional key to control autoimmunity and cancer

Novel anti-cancer medicine could improve current therapy for ER+ breast cancer

Moderate physical activity reduces frequent hospital admissions in middle and older age

Twist Bioscience Identifies Competitive Antibodies for SARS-CoV-2

BIOCAD becomes Vector’s industrial partner to develop COVID-19 vaccine

New preclinical study shows promise for treating necrotizing enterocolitis

Activation of estrogen receptor can impede growth of pancreatic cancer cells

FDA approves SFU professor's invention to wean COVID-19 patients from ventilators

Researchers examine role of immune response in COVID-19 patients

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

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