Clinical Trial News and Research

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Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

A new clinical trial is testing the effectiveness of chemotherapy treatment following surgery for a subset of pancreatic cancer patients.

19 May 2023

Tonsillectomy found to be cost-effective for adults with recurrent severe sore throats

Scientists say tonsil removal is both clinically and cost effective for adults who get recurrent severe sore throats.

18 May 2023

Majority of people in the UK would consider taking part in a clinical trial, survey reveals

The majority of people in the UK (68%) would consider taking part in a clinical trial, it has been revealed today (19 May), while half of Brits would also be willing to take part in an early phase clinical trial.

18 May 2023

Bioresorbable vascular scaffolds may be just as effective as drug-eluting metal stents for treating heart disease patients

First-generation bioresorbable vascular scaffolds (BVS) may be just as effective as drug-eluting metallic stents, which are currently the standard treatment for heart disease patients undergoing percutaneous coronary intervention (PCI).

17 May 2023

Clinical trial shows efficacy and safety of brepocitinib for treating adults with psoriatic arthritis

Brepocitinib is an oral drug that inhibits certain enzymes involved in inflammation - called tyrosine kinase 2 and Janus kinase 1 - and is being tested for the treatment of several immunological diseases.

17 May 2023

Closed Loop Medicine and Pharmanovia enter a co-development partnership for precision medicine combination therapeutics

Closed Loop Medicine Ltd, a leading TechBio company, today announced that they have entered a global co-development partnership.

From Closed Loop Medicine 17 May 2023

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

As part of the Foundation for the National Institutes of Health Accelerating Medicines Partnership Bespoke Gene Therapy Consortium, Nemours Children's Health has been chosen to conduct a first-of-its-kind gene therapy clinical trial for Morquio A syndrome.

16 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Henry Ford Health Interventional cardiologists William O'Neill, M.D., and Khaldoon Alaswad, M.D., took a page out of the medical history books by performing a new coronary bypass procedure replicated from one not used in decades to treat a patient living with crippling angina - a severe symptom of coronary artery disease.

15 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study aims to optimize radiotherapy treatment for patients with anal cancer

Reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects, recent clinical trial results have shown.

15 May 2023

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.

15 May 2023

Placenta plays a more significant role in developing schizophrenia than previously known

More than 100 genes linked to the risk of schizophrenia seem to cause illness because of their role in the placenta rather than in the developing brain, according to a new study led by the Lieber Institute for Brain Development.

15 May 2023

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

A recent clinical trial showed that the drug combination of cemiplimab plus platinum chemotherapy can prolong survival in patients with advanced lung cancer when compared with placebo plus platinum chemotherapy. Now an analysis published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, indicates that cemiplimab plus platinum chemotherapy also affects quality of life compared to chemotherapy alone.

13 May 2023

Clinical Trial News and Research

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

Tonsillectomy found to be cost-effective for adults with recurrent severe sore throats

Majority of people in the UK would consider taking part in a clinical trial, survey reveals

Bioresorbable vascular scaffolds may be just as effective as drug-eluting metal stents for treating heart disease patients

Clinical trial shows efficacy and safety of brepocitinib for treating adults with psoriatic arthritis

Closed Loop Medicine and Pharmanovia enter a co-development partnership for precision medicine combination therapeutics

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study aims to optimize radiotherapy treatment for patients with anal cancer

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

Placenta plays a more significant role in developing schizophrenia than previously known

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

An evaluation of the effect of maternal vitamin B12 supplementation on postpartum infant growth and neurodevelopment

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

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