Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Lithium corrects radiation damage to brain in young cancer patients

A new study on mice, published online in the journal Molecular Psychiatry, on November 14, 2019, shows that the intermittent use of lithium, which is widely used to stabilize the mood in conditions such as bipolar disorder, can correct memory and learning losses due to radiation therapy to the brain in very young animals, even when the lithium is given long after the injury.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.

14 Nov 2019

Leukemia type B cell can transform into a macrophage through epigenetic changes

All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects.

13 Nov 2019

Fresh light on why aggressive breast tumors form and how they can be treated

New research presented at the Society for Endocrinology annual conference in Brighton appears to identify novel methods of therapy for an aggressive type of breast cancer as well as uncovering potential causative factors. The focus of the study is to show how common chemicals present in our surroundings are possibly putting women at risk of a type of breast cancer called triple negative breast cancer (TNBC).

12 Nov 2019

Medical steroid use could push up diabetes risk

Glucocorticoids (GCs), or steroids, as they are popularly called, are often prescribed for their anti-inflammatory effects in a host of conditions including acute asthmatic attacks, allergies, and arthritis. However, are they doing good or harm?

12 Nov 2019

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

Recent studies have found a high genetic similarity of the psychiatric diseases schizophrenia and bipolar disorder, whose disease-specific changes in brain cells show an overlap of more than 70 percent.

12 Nov 2019

Protein that drives pancreatic cancer growth could be new treatment target

A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified by researchers at the Crick.

12 Nov 2019

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Rutgers Cancer Institute of New Jersey researcher Hossein Khiabanian, PhD, has received a $600,000 Translational Award from the V Foundation for Cancer Research to study chronic lymphocytic leukemia with the aim of developing research models that may help investigators better understand how CLL cells are influenced by new therapies.

11 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Scientists discover role for vitamin D in melanoma

A new study published in Cancer Research suggests that high levels of vitamin D may reduce the aggressive nature of melanoma cells and improve survival rates.

8 Nov 2019

Human heart cells show remarkable adaptability during and after spaceflight

Heart muscle cells derived from stem cells show remarkable adaptability to their environment during and after spaceflight, according to a study publishing November 7 in the journal Stem Cell Reports.

8 Nov 2019

New method to construct personalized gene networks may contribute to personalized treatments

Researchers at Penn State College of Medicine have developed a new method to model how genes interact with each other -- and it may someday contribute to the development of personalized treatments for patients.

7 Nov 2019

Study sheds light on potential strategy for treating Charcot-Marie-Tooth

An unexpected finding from the Scripps Research laboratory of Xiang-Lei Yang, PhD, has illuminated a potential strategy for treating the inherited neurological disease Charcot-Marie-Tooth (CMT), for which there is no approved medicine today.

7 Nov 2019

Study uncovers how cells 'forget their past' while developing into a specific cell

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’.

7 Nov 2019

Myocardial infarction model developed using cardiomyocytes

Researchers at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences developed a model of myocardial infarction using cardiomyocytes differentiated from human induced pluripotent stem cells.

7 Nov 2019

NJIT professor receives Fulbright U.S. Scholar Award, joins circadian clock research project

Casey Diekman, associate professor of mathematics at New Jersey Institute of Technology (NJIT), has been named recipient of a prestigious Fulbright U.S. Scholar Program Award to the United Kingdom in Mathematical Biology.

6 Nov 2019

Researchers reveal mechanisms that lead to onset of Type 1 diabetes

Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to the onset of Type 1 Diabetes (T1D).

6 Nov 2019

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments.

6 Nov 2019

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

Eisai Co., Ltd. announced today that it has entered into an agreement to transfer the rights to receive royalties on the sales outside of Japan for an investigational anti-cancer agent tazemetostat (generic name) to Royalty Pharma.

5 Nov 2019

Gene Expression News and Research

Further Reading

Lithium corrects radiation damage to brain in young cancer patients

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

Leukemia type B cell can transform into a macrophage through epigenetic changes

Fresh light on why aggressive breast tumors form and how they can be treated

Medical steroid use could push up diabetes risk

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

Protein that drives pancreatic cancer growth could be new treatment target

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Scientists discover role for vitamin D in melanoma

Human heart cells show remarkable adaptability during and after spaceflight

New method to construct personalized gene networks may contribute to personalized treatments

Study sheds light on potential strategy for treating Charcot-Marie-Tooth

Study uncovers how cells 'forget their past' while developing into a specific cell

Myocardial infarction model developed using cardiomyocytes

NJIT professor receives Fulbright U.S. Scholar Award, joins circadian clock research project

Researchers reveal mechanisms that lead to onset of Type 1 diabetes

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

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