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The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Researchers identified SARS-CoV-2 spike surfaces involved in binding to host cell membranes.

6 Jul 2022

Widely used hospital gowns show signs of exposing workers to infection

Disposable gowns designed to deflect the splatter of bodily fluids, used in thousands of U.S. hospitals, have underperformed in recent and ongoing laboratory tests and may fall short of safety standards, leaving health care workers with a greater risk of infection than advertised.

6 Jul 2022

Daily avocado consumption linked to better diet quality and decrease in LDL cholesterol

Eating one avocado a day for six months was found to have no effect on belly fat, liver fat or waist circumference in people with overweight or obesity, according to a new study. However, it did lead to a slight decrease in unhealthy cholesterol levels.

5 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

New method helps determine alcohol consumption in fatty liver disease

It is important to know whether patients have non-alcoholic fatty liver disease (NAFLD) or alcohol-related liver disease (ALD), as this distinction plays a key role in treatment and prognosis but cannot be reliably determined by established diagnostic means.

5 Jul 2022

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

In a new study, researchers assessed the influence of severe coronavirus disease 2019 on scrotal infections.

5 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Two-step synthesis procedure produces amino acid Schiff base Cu (II) complexes within 10 minutes

Ever since their development in the late 19th century, Schiff bases have been a popular group of organic compounds, owing to their wide variety of desirable properties.

4 Jul 2022

Machine-learning algorithms can help distinguish acute cholangitis and alcohol-associated hepatitis

Acute cholangitis is a potentially life-threatening bacterial infection that often is associated with gallstones. Symptoms include fever, jaundice, right upper quadrant pain, and elevated liver enzymes.

1 Jul 2022

New study investigates the epigenetic drift of time passing

A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, "Time makes histone H3 modifications drift in mouse liver."

30 Jun 2022

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

Two levels underground, Chicago's Field Museum has a secret bunker. The sub-basement Collections Resource Center houses millions of biological specimens for scientists around the world to use in their research, including countless bottles and jars containing pickled fish, lizards, and snakes, arranged like a library.

30 Jun 2022

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Scientists exploring how our immune system responds to pathogens and cancers have ramped up their attention to CD8+ T cells, which are deployed in response to infections and malignancies and equipped to remember the identities of malicious invaders.

29 Jun 2022

Study finds above-average rates of mortality from gastric cancer in South Florida

South Florida counties have above-average rates of mortality from gastric cancer, according to a new study published in the journal Gastroenterology by investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

29 Jun 2022

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

New tissue model helps trace the steps involved in liver regeneration

The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months.

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Chemically modified rocaglates have a stronger effect against viral replication

Hepatitis E virus (HEV) is widespread, and so far there is no effective drug. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses.

27 Jun 2022

Liver News and Research

The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Widely used hospital gowns show signs of exposing workers to infection

Daily avocado consumption linked to better diet quality and decrease in LDL cholesterol

Researchers explore how diet and feeding patterns affect intestinal microbes

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

New method helps determine alcohol consumption in fatty liver disease

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

Two-step synthesis procedure produces amino acid Schiff base Cu (II) complexes within 10 minutes

Machine-learning algorithms can help distinguish acute cholangitis and alcohol-associated hepatitis

New study investigates the epigenetic drift of time passing

New approaches for getting and maximizing usable DNA from decades-old pickled specimens

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Study finds above-average rates of mortality from gastric cancer in South Florida

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

New tissue model helps trace the steps involved in liver regeneration

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

Chemically modified rocaglates have a stronger effect against viral replication

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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