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Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects' nerve cells that are able to fine-tune their ability to detect particularly "welcoming" odors in human skin.

21 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through the body.

20 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

17 Feb 2023

Mechanistic insight into how receptor location is the key for psychedelic drug effects

Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells.

17 Feb 2023

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Researchers used a non-human primate model to show that Sotrovimab, a commercial mAb also known as Xevudy, was fully effective against SARS-CoV-2 Omicron BA.5 sub-lineage and its derivatives, such as BQ.1.1.

17 Feb 2023

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

UVA Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.

16 Feb 2023

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Two classes of drugs prescribed off-label for some patients with Type 1 diabetes can provide significant benefits but also come with health concerns, according to a study by UT Southwestern Medical Center researchers.

16 Feb 2023

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Researchers from Karolinska Institutet have discovered that the genes encoding our T cell receptors vary greatly between persons and populations, which may explain why we respond differently to for example infections.

16 Feb 2023

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

In 2021, 100,306 Americans died from drug overdoses – a 28.5 percent increase from the prior year – with 75,673 attributed to opioids.

16 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Receptor News and Research

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Mapping specialized receptors on mosquito nerve cells reveals why the insects are more attracted to some humans

Structure of DREADD designer receptor could pave the way for creating next generation tools

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Are SGLT2 inhibitors the next blockbuster drug?

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Mechanistic insight into how receptor location is the key for psychedelic drug effects

Research reports full efficacy of Sotrovimab against BQ.1.1 viral replication in a non-human primate challenge model

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

Smoking and vaping may put healthy young people at risk of severe COVID

New insights into the driving factors of COVID-19 dynamics in England

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Changes in SARS-CoV-2 antibody titers after COVID-19 vaccination

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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