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New computer model can accurately predict the communities formed by human gut microbes

The communities formed by human gut microbes can now be predicted more accurately with a new computer model developed in a collaboration between biologists and engineers, led by the University of Michigan and the University of Wisconsin.

7 Jul 2022

New biosensor system derived from E. coli bacteria could accelerate drug development

For more affordable, sustainable drug options than we have today, the medication we take to treat high blood pressure, pain or memory loss may one day come from engineered bacteria, cultured in a vat like yogurt.

7 Jul 2022

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

In a discovery that could spur the development of new therapies for more than 40 million HIV patients worldwide, scientists from Rutgers University and the Salk Institute determined the molecular structure of the HIV Pol polyprotein, a protein that plays a critical role in helping the virus propagate itself and spread throughout the body.

7 Jul 2022

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Sickle cell disease is an extremely debilitating condition that affects up to 40% of the population in African countries, with patients suffering episodes of excruciating pain, organ damage and reduced life-expectancy.

7 Jul 2022

SARS-CoV-2 RBD vulnerability discovered - target for antibodies against variants

A new study successfully identified a potent neutralization epitope in SARS-related coronaviruses.

6 Jul 2022

COVID-19 impairs the insulin/IGF signaling pathway

Scientists evaluate the impact of SARS-CoV-2 on the insulin/IGF signaling pathway.

6 Jul 2022

Study: Lactobacilli living in female urinary tract's microbiome can kill nearby pathogenic bacteria

Lactobacilli that live in the human female urinary tract's microbiome are competitive and kill nearby pathogenic bacteria, according to the first study of its kind by a team led by microbiologist Dr. Tanya Sysoeva of The University of Alabama in Huntsville.

6 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

New model reveals cancer-driving mutations

In this interview, News-Medical speaks to Maxwell Sherman, an MIT graduate student and one of the lead authors of a study that used a new method to investigate cancer genomes.

6 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

How is the microbiome of an infant influenced by mother's bacteria?

A recent study explores the sources and functional importance of certain key species in the mother-infant transmission of the microbiota.

5 Jul 2022

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.

5 Jul 2022

BICO; Combining Life Sciences Solutions to Further Human Health

As part of our SLAS Europe 2022 coverage, we speak to Héctor Martínez, CTO of BICO, about the technology and services they offer within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 5 Jul 2022

Singapore researchers develop a bio-functional thermogel to prevent retinal scarring

Singapore scientists have developed a bio-functional thermogel, a type of synthetic polymer, to prevent retinal scarring caused by failed retinal detachment repair surgery.

4 Jul 2022

Remdesivir resistance in renal transplant patients with long COVID-19

A new study has reported two renal transplant cases, in which individuals, after being exposed to remdesivir, developed a resistance to the drug.

1 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

Crystal structure of a human endogenous reverse transcriptase revealed

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

30 Jun 2022

Study of condensates offers new hope for the treatment of neurodegenerative diseases

The Körber European Science Prize 2022, endowed with one million euros, is to be awarded to the British cell biologist Anthony Hyman.

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

Therapeutics News and Research

New computer model can accurately predict the communities formed by human gut microbes

New biosensor system derived from E. coli bacteria could accelerate drug development

Knowledge of HIV Pol polyprotein's structure could spur the development of new therapies

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

SARS-CoV-2 RBD vulnerability discovered - target for antibodies against variants

COVID-19 impairs the insulin/IGF signaling pathway

Study: Lactobacilli living in female urinary tract's microbiome can kill nearby pathogenic bacteria

Beyond COVID-19: the potential future applications of mRNA vaccines

New model reveals cancer-driving mutations

Novel inhalable COVID-19 vaccine

How is the microbiome of an infant influenced by mother's bacteria?

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

BICO; Combining Life Sciences Solutions to Further Human Health

Singapore researchers develop a bio-functional thermogel to prevent retinal scarring

Remdesivir resistance in renal transplant patients with long COVID-19

Combining AI and Zebrafish to Accelerate Drug Discovery

HIV accelerates epigenetic aging soon after initial HIV infection

Crystal structure of a human endogenous reverse transcriptase revealed

Study of condensates offers new hope for the treatment of neurodegenerative diseases

Casirivimab/imdevimab improve outcomes in early COVID-19

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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