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Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.

19 Oct 2013

Study shows narrow-spectrum UV light reduces surgical infections without damaging tissue

Despite major efforts to keep operating rooms sterile, surgical wound infections remain a serious and stubborn problem, killing up to 8,200 patients a year in the U.S. A study by Columbia University Medical Center (CUMC) researchers suggests that narrow-spectrum ultraviolet (UV) light could dramatically reduce such infections without damaging human tissue.

17 Oct 2013

Discovery of neural firing-rate set point opens door to possible treatment for devastating disorders

As we learn and develop, our neurons change. They make new pathways and connections as our brain processes new information. In order to do this, individual neurons use an internal gauge to maintain a delicate balance that keeps our brains from becoming too excitable.

17 Oct 2013

New $1.9M research grant to support investigators to detect tumors in earliest stages of formation

The National Cancer Institute's new Provocative Questions research funding program has awarded a prestigious grant to researchers at the Case Comprehensive Cancer Center and Case Western Reserve University's Schools of Medicine and Engineering to study tumor detection at the earliest stages of growth.

16 Oct 2013

Crown Bioscience enters into collaboration with Xstrahl for radiation biology research

Crown Bioscience, Inc., a leading global drug discovery and development service company, today announces that it has entered into a collaboration with Xstrahl Ltd, a leading designer and manufacturer of X-Ray solutions for radiation biology research.

From Xstrahl 15 Oct 2013

Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.

15 Oct 2013

Scientists develop new method to regenerate cartilage

Unlike our bones, the cartilage inside our joints is not vascularized (i.e., it has no blood vessels). This is one reason why cartilage does not heal well after an injury. In athletes in particular, joint injuries often result in cartilage degeneration and arthritis. The process is chronic and irreversible, and to this day, no effective treatment exists.

12 Oct 2013

CHD Bioscience's lead product can help mitigate increasing threat of HAIs

According to a recent report issued by the Centers for Disease Control, every year more than two million people develop infections that are resistant to antibiotics. Specific healthcare-associated infections are classified as urgent threats and affect approximately 1.7 million people annually across the United States, leading to death in nearly 99,000 patients.

9 Oct 2013

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists.

7 Oct 2013

Scientists uncover new approach to develop induced pluripotent stem cells for in vivo disease modeling

In a paper in Cell Stem Cell, a team led by researchers in the Boston Children's Hospital's Stem Cell Transplantation Program reports a new approach for turning induced pluripotent stem cells (iPSCs) into hematopoietic stem and progenitor cells for in vivo disease modeling.

4 Oct 2013

Researchers develop new approach to combat tubercle bacillus

A new approach to combating the tubercle bacillus, the microorganism that kills some 1.5 million people in the world each year, has been developed by a French-British team including scientists from CNRS, Inserm, the Institut Curie and Université Toulouse III - Paul Sabatier.

2 Oct 2013

Scientists discover two new compounds that could help treat CF patients having common mutation

Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes), led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation.

30 Sep 2013

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

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27 Sep 2013

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

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27 Sep 2013

Reliable blood flow imaging system developed with inexpensive off-the-shelf commercial parts

Tracking blood flow in the laboratory is an important tool for studying ailments like migraines or strokes and designing new ways to address them. Blood flow is also routinely measured in the clinic, and laser speckle contrast imaging (LSCI) is one way of measuring these changes; however, this technique requires professional-grade imaging equipment, which limits its use.

27 Sep 2013

Targeting cell-division cycle may lead to improved outcomes for patients with medulloblastoma

A new experimental approach to treating a type of brain cancer called medulloblastoma has been developed by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham).

26 Sep 2013

Spanish scientists discover melatonin consumption helps control weight gain

Melatonin is a natural hormone segregated by the body and melatonin levels generally increase in the dark at night. It is also found in fruit and vegetables like mustard, Goji berries, almonds, sunflower seeds, cardamom, fennel, coriander and cherries.

26 Sep 2013

Lpath receives NIH SBIR grant to investigate effect of Lpathomab compound on diabetic neuropathy

Lpath, Inc., the industry leader in lipidomics-based therapeutics, announced receipt of a Notice of Grant Award from the National Institutes of Health (NIH). This $145,000 Phase 1 SBIR grant will support the study of Lpath's therapeutic monoclonal antibody, Lpathomab™, in animal models of diabetic neuropathic pain and diabetic neuropathy.

23 Sep 2013

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.

21 Sep 2013

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

At the 2013 World Molecular Imaging Congress (WMIC, www.wmicmeeting.org), Bruker today announced the world’s first Magnetic Particle Imaging (MPI) system, an entirely new technology for preclinical imaging. The addition of MPI as a complementary preclinical imaging technique for disease studies, translational research and drug discovery, has significant potential in helping researchers gain new insights into disease processes at the organ, cellular and molecular level.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2013

in vivo News and Research

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

Study shows narrow-spectrum UV light reduces surgical infections without damaging tissue

Discovery of neural firing-rate set point opens door to possible treatment for devastating disorders

New $1.9M research grant to support investigators to detect tumors in earliest stages of formation

Crown Bioscience enters into collaboration with Xstrahl for radiation biology research

Cdk5 protein may play crucial role in deadly form of thyroid cancer

Scientists develop new method to regenerate cartilage

CHD Bioscience's lead product can help mitigate increasing threat of HAIs

ERK pathway discovery may provide therapeutic options for treating drug addictions

Scientists uncover new approach to develop induced pluripotent stem cells for in vivo disease modeling

Researchers develop new approach to combat tubercle bacillus

Scientists discover two new compounds that could help treat CF patients having common mutation

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

Ablynx Nets Another $33.7M From Merck Serono As Partnership Expands

Reliable blood flow imaging system developed with inexpensive off-the-shelf commercial parts

Targeting cell-division cycle may lead to improved outcomes for patients with medulloblastoma

Spanish scientists discover melatonin consumption helps control weight gain

Lpath receives NIH SBIR grant to investigate effect of Lpathomab compound on diabetic neuropathy

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

World’s first preclinical Magnetic Particle Imaging (MPI) system announced by Bruker

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