Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

According to new research, epigenetic changes found in the offspring exposed to maternal smoking during pregnancy or in current smokers are linked to smoking-related diseases in adulthood.

13 Nov 2018

Study finds why obesity both fuels cancer growth and helps immunotherapy to kill tumors

A groundbreaking new study by UC Davis researchers has uncovered why obesity both fuels cancer growth and allows blockbuster new immunotherapies to work better against those same tumors.

13 Nov 2018

Saliva-based RNA test could improve ability to accurately identify children with ASD

Newly published research shows that a saliva-based biomarker panel and associated algorithm could improve the ability to accurately identify children with autism spectrum disorder (ASD) in its earliest stages, announced Quadrant Biosciences Inc.

9 Nov 2018

Researchers discover gene signature biomarker that may predict patients' response to immune therapy

Scientists led by Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have discovered a gene signature biomarker that may predict which patients will respond - or not - to immune therapy.

8 Nov 2018

Researchers create new accessible staging system to predict survival for patients with AL amyloidosis

A new staging system developed with a more accessible test to predict the chance of survival in patients living with light chain (AL) amyloidosis.

8 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Special chemical that makes brain tumours glow pink to help neurosurgeons operate

A clinical trial has shown that a special chemical makes brain tumours glow pink. This can help neurosurgeons operate easily on them and remove them completely and safely say the researchers. The results of this study were presented at the 2018 NCRI Cancer Conference in Glasgow.

4 Nov 2018

Chronic inflammation linked with increased risk of multiple diseases and shorter lifespan

Researchers have elucidated the disease risk underlying a biomarker predictive of shorter lifespan.

2 Nov 2018

Insilico Medicine to present latest advances in drug development at Supply Side West Conference

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest advances in modern drug development at the Supply Side West Conference in Las Vegas, 8-9 of November.

2 Nov 2018

Study finds evidence of lasting effects from head injuries at younger age than expected

There have been more and more cases confirming that repeated hits to the head have lifelong consequences for professional football players, but a new study by Orlando Health in collaboration with the Concussion Neuroimaging Consortium finds evidence of lasting effects from head injuries at a much younger age than expected.

2 Nov 2018

MCG selected as designated laboratory for NCI-MATCH trial

The Georgia Esoteric and Molecular Laboratory at the Medical College of Georgia at Augusta University has been selected as a designated laboratory for the National Cancer Institute's Molecular Analysis for Therapy Choice, or MATCH trial, which is assessing the effectiveness of targeting cancer-causing gene changes rather than cancer type.

1 Nov 2018

Tick-borne disease is multiple microbial in nature

A study recently published in Scientific Reports discovered that 65% of Lyme disease patients irrespective of their disease stage respond to several microbes.

1 Nov 2018

NeuroPointDX launches NPDX AA test to identify metabolic subtypes associated with autism

NeuroPointDX, a division of Stemina Biomarker Discovery, today announced the commercial launch of its NPDX AA test, which identifies metabolic subtypes associated with autism spectrum disorder.

1 Nov 2018

Researchers discover biomarker for most common type of heart failure

A team led by a Cedars-Sinai physician-scientist has discovered a biomarker--a protein found in the blood--for the most common type of heart failure, a new study published today in JAMA Cardiology shows.

1 Nov 2018

Study offers hope of early detection, treatment of liver cancer

Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments.

31 Oct 2018

Insilico to present its research in AI for drug discovery at BioCentury China HealthCare Summit

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its research in AI for drug discovery at BioCentury China HealthCare Summit in Shanghai, 13-14 of November.

31 Oct 2018

Researchers develop diagnostic test to determine risk of developing malignant breast cancer

Currently, with a pre-malignant breast cancer diagnosis from a biopsy, there are three options: observation, chemoprevention or surgery, all of which require a patient to make decisions while operating from a place of fear and unknown outcomes.

31 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Quantum dot-based FISH method enhances cell imaging

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes.

30 Oct 2018

Biomarker News and Research

Further Reading

Epigenetic link found between prenatal exposure to maternal smoking and offspring's cardio-metabolic health

Study finds why obesity both fuels cancer growth and helps immunotherapy to kill tumors

Saliva-based RNA test could improve ability to accurately identify children with ASD

Researchers discover gene signature biomarker that may predict patients' response to immune therapy

Researchers create new accessible staging system to predict survival for patients with AL amyloidosis

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Special chemical that makes brain tumours glow pink to help neurosurgeons operate

Chronic inflammation linked with increased risk of multiple diseases and shorter lifespan

Insilico Medicine to present latest advances in drug development at Supply Side West Conference

Study finds evidence of lasting effects from head injuries at younger age than expected

MCG selected as designated laboratory for NCI-MATCH trial

Tick-borne disease is multiple microbial in nature

NeuroPointDX launches NPDX AA test to identify metabolic subtypes associated with autism

Researchers discover biomarker for most common type of heart failure

Study offers hope of early detection, treatment of liver cancer

Insilico to present its research in AI for drug discovery at BioCentury China HealthCare Summit

Researchers develop diagnostic test to determine risk of developing malignant breast cancer

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Quantum dot-based FISH method enhances cell imaging

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

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