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Peptide hydrogel boosts antibiotic effectiveness against resistant bacteria

Research from Chalmers University of Technology, Sweden, shows that resistant bacteria can regain susceptibility to antibiotics when the treatment is combined with a material equipped with antibacterial peptides.

19 Nov 2024

Global analysis reveals striking disparities in the cost and availability of cancer drugs

A recent analysis reveals striking disparities in the cost and availability of cancer drugs across different regions of the globe, with significant gaps between high- and low-income countries.

19 Nov 2024

Study: 40% of newly diagnosed heart failure patients also have atrial fibrillation

A new study by researchers at Intermountain Health in Salt Lake City finds that 40 percent of newly diagnosed heart failure patients also have atrial fibrillation – a combination of cardiac disorders that researchers found results in significantly poorer outcomes for patients.

19 Nov 2024

MSU researchers develop method for earlier disease detection using blood proteins

Medical professionals have long known that the earlier a disease is detected, the higher the chance for a better patient outcome.

19 Nov 2024

Anti-obesity drugs show promise in improving cardiovascular health beyond weight loss

Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to several new papers published in JACC, the flagship journal of the American College of Cardiology, that are being simultaneously presented at the American Heart Association's 2024 Scientific Sessions.

19 Nov 2024

Small Solutions for Big Problems in Drug Discovery and Delivery

Ijeoma Uchegbu discusses nanomedicine's role in improving medication adherence and developing non-addictive pain relief solutions at ELRIG Drug Discovery 2024.

19 Nov 2024

Multiple sclerosis drug could help individuals with reduced working memory

Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like schizophrenia or depression.

19 Nov 2024

Nanoplastics may lead to the development of antibiotic resistance

Minuscule particles of plastic are not only bad for the environment. A study led from Umeå University, Sweden, has shown that the so-called nanoplastics which enter the body also can impair the effect of antibiotic treatment.

18 Nov 2024

New insights into pain signaling could lead to better chronic pain treatment

When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers at Linköping University, Sweden, have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals.

18 Nov 2024

Rising temperatures fuel global spread of dengue infections

Climate change is having a massive global impact on dengue transmission, accounting for 19% of the current dengue burden, with a potential to spark an additional 40%-60% spike by 2050 - and by as much as 150%-200% in some areas - according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

18 Nov 2024

Study uncovers key mechanism behind HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

18 Nov 2024

GLP-1 drugs, like semaglutide, lower risk of hospitalizations for alcohol use disorder

Findings suggest semaglutide and other GLP-1 agonists may significantly reduce alcohol use disorder hospitalizations, warranting further clinical investigation.

18 Nov 2024

SGLT2 inhibitor canagliflozin shown to improve kidney oxygenation in diabetes patients

Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention.

18 Nov 2024

NSAIDs raise bleeding risk in patients taking blood thinners

People who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen, according to research published in the European Heart Journal [1] today (Monday).

18 Nov 2024

New oral painkiller developed for chronic abdominal pain

University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.

18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

Antiseizure medications during pregnancy linked to neurodevelopmental risks in children

Children born to mothers who take antiseizure medications to manage seizures and psychiatric conditions during pregnancy may face increased risks of neurodevelopmental conditions, according to new data from researchers at Drexel's Dornsife School of Public Health.

15 Nov 2024

Researchers discover how mutations disrupt protein splicing and cause disease

An international research team has uncovered a new mechanism crucial to the production of cellular proteins.

15 Nov 2024

Gut microbiome found to play key role in chronic disease progression

The gut microbiome, an ecosystem of trillions of microorganisms in the human digestive tract, has been increasingly linked to chronic diseases.

15 Nov 2024

Obesity crisis in the U.S. expected to worsen by 2050

Over the past three decades, there has been a startling increase in the prevalence of obesity across the USA, at least doubling in adult men and women (aged 25 and older) and older female and male adolescents (aged 15-24 years) since 1990, with the number of people living with overweight and obesity reaching over 208 million in 2021 - a trend set to continue in the coming decades without significant reform, according to a major new analysis from the Global Burden of Disease Study Collaborator Network, published in The Lancet.

15 Nov 2024