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Stem cell therapy rescues motor neurons in ALS model

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

3 Aug 2007

New point of attack for future liver cancer treatments

The linking of two signalling pathways in the cells of liver tumours has a clear influence on their malignancy.

1 Aug 2007

Stem cell therapy rescues motor neurons in amyotrophic lateral sclerosis model

31 Jul 2007

Good signal for liver tumour therapy

The linking of two signalling pathways in the cells of liver tumours has a clear influence on their malignancy. Activation of the platelet-derived growth factor (PDGF) messenger molecule is decisive for this linking.

30 Jul 2007

Eat a good diet and exercise to live longer

The traditional prescriptions for a healthy life sensible diet, exercise and weight control extend life by reducing signaling through a specific pathway in the brain, according to Howard Hughes Medical Institute researchers who discovered the connection while studying long-lived mice.

20 Jul 2007

Critical link found between two proteins found in brain tumors

MIT researchers have identified a critical link between two proteins found in brain tumors, a discovery that could eventually help treat a form of brain cancer that kills 99 percent of patients.

20 Jul 2007

Protein kinase G holds promise for cancer treatment

An enzyme that cancer cells eliminate, apparently so they can keep proliferating, may hold clues to more targeted, effective cancer treatment, scientists say.

19 Jul 2007

Protein km23 - potential target for ovarian cancer treatment

A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth.

17 Jul 2007

Interleukin-6 - new target in the battle against Ras-induced cancers

In an upcoming Genes & Development paper, Dr. Christopher Counter and colleagues at the Duke University Medical Center have identified IL6 as a new target in the battle against Ras-induced cancers.

16 Jul 2007

Startling discovery on the development of human embryonic stem cells

In this week's Nature, researchers of the McMaster Cancer and Stem Cell Research Institute show that human embryonic stem (ES) cells can actually produce distinctive niche cells, which then release stem-cell nourishing proteins to help keep their parents ticking over.

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

New gene mutation linked to frontotemporal dementia

Researchers have identified a new gene mutation linked to frontotemporal dementia, according to a study published in the July 10, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

10 Jul 2007

Debate on folic acid fortification

Since the institution of nationwide folic acid fortification of enriched grains in the mid 1990s, the number of infants born in the United States and Canada with neural tube defects has declined by 20 percent to 50 percent.

10 Jul 2007

Scientists discover protein instrumental to brain development and repair

Scientists at Children's National Medical Center have demonstrated conclusively that a specific protein and its signaling activity are instrumental in myelination and remyelination, processes essential to the creation and repair of the brain's white matter.

9 Jul 2007