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Response to a third SARS-CoV-2 vaccine dose amongst immunocompromised

In a research paper recently uploaded to the preprint server medRxiv* by Schrezenmeier et al. (August 12th, 2021) the potential benefit of three vaccine doses in either a homogenous or heterogeneous dosing regimen amongst kidney transplant patients is assessed, finding that the search for viable vaccination approaches amongst these patients remains an urgent medical need.

16 Aug 2021

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

Removing race as a factor in a kidney function-estimating equation used to guide cancer treatment dosing and eligibility may decrease the proportion of Black patients recommended to receive full doses of anticancer drugs.

16 Aug 2021

Quick, inexpensive leptospirosis test strip kit to help lower death and disability risk

The Faculty of Medicine, Chulalongkorn University has brought out a quick, inexpensive, and easy-to-use leptospirosis test strip kit to help lower the risk of disability from internal organ failure and death, with the hopes of distributing them to community hospitals across the country.

14 Aug 2021

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Scientists with the Ajmera Transplant Centre at UHN have conducted a first-in-the-world randomized placebo-controlled trial of third dose COVID-19 booster vaccine for transplant patients that shows substantially improved protection.

14 Aug 2021

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

An accurate assessment of a patient's kidney function is critical for determining eligibility for anticancer treatments.

14 Aug 2021

Study exposes the dire need for new clinical risk management tools to prevent COVID-19 deaths

A new study exposes the dire need for new clinical risk management tools to help hospital healthcare workers prevent the deaths and intensive care admissions of Black, Asian and minority ethnic (BAME) COVID-19 patients with pneumonia, say researchers.

13 Aug 2021

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A - a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection - is controlled.

13 Aug 2021

‘I don’t want to risk my life for a paycheck’: Immunosuppressed people grapple with returning to work

Elizabeth Groenweghe got a kidney transplant 14 years ago. She now takes several medications to prevent her body from rejecting her transplant organ. But these medications also weaken her immune system, putting her at higher risk of becoming seriously ill if she catches covid-19.

13 Aug 2021

Researchers map the impact of Covid-19 on the mental well-being of Israelis

During the six weeks between the end of the first COVID-19 outbreak in Israel and the beginning of the second one (late April to early June of 2020), researchers at the Weizmann Institute of Science initiated a study that encompassed more than 12,000 responses from nearly 5,000 respondents to digital questionnaires, in an attempt to assess and understand the mental toll of the pandemic on the country's adult population.

12 Aug 2021

Study unlocks genetic treasure chest for chronic kidney disease

Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease.

12 Aug 2021

Penn study discovers a targetable vulnerability in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) cells can be destroyed and kept from multiplying by inhibiting the HDL cholesterol receptor SCARB1, according to research from the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2021

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

A pilot study has begun to assess the antibody response to a third dose of an authorized COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine.

10 Aug 2021

Polymer-based coating for blood vessels can reduce organ rejection following a transplant

Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted.

9 Aug 2021

Resistance exercise regulates fat cell metabolism at a molecular level, study finds

Findings from a new University of Kentucky College of Medicine and College of Health Sciences study add to growing evidence that resistance exercise has unique benefits for fat loss.

9 Aug 2021

New insight into impact of SARS-CoV-2 mutations on receptor binding

A recent study by Canadian researchers, currently available on the bioRxiv* preprint server, contributes to the growing body of literature on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by appraising the impact of single mutations on their overall antigenicity and binding affinity for the angiotensin-converting enzyme 2 (ACE2) receptor.

9 Aug 2021

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Pooled results from recent clinical trials indicate that an oral drug called roxadustat is an effective treatment for anemia in patients with chronic kidney disease.

6 Aug 2021

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

A recent clinical trial described in CJASN has examined the potential of vitamin D supplementation for protecting the kidney health of individuals with pre-diabetes.

6 Aug 2021

Clarity on covid count: Pandemic’s toll on seniors extended well beyond nursing homes

As covid-19 resurges across the country, driven by the highly infectious delta variant, experts are extending our understanding of the pandemic's toll on older adults — the age group hit hardest by the pandemic.

6 Aug 2021

Dialysis patients' response to COVID19 vaccine type

The researchers at Standford University evaluated the humoral vaccination response of 2,099 fully vaccinated patients undergoing dialysis.

5 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Kidney News and Research

Response to a third SARS-CoV-2 vaccine dose amongst immunocompromised

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

Quick, inexpensive leptospirosis test strip kit to help lower death and disability risk

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

Study exposes the dire need for new clinical risk management tools to prevent COVID-19 deaths

Understanding how to regulate key enzyme may lead to new treatments for cancers, viral infections

‘I don’t want to risk my life for a paycheck’: Immunosuppressed people grapple with returning to work

Researchers map the impact of Covid-19 on the mental well-being of Israelis

Study unlocks genetic treasure chest for chronic kidney disease

Penn study discovers a targetable vulnerability in clear cell renal cell carcinoma

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

Polymer-based coating for blood vessels can reduce organ rejection following a transplant

Resistance exercise regulates fat cell metabolism at a molecular level, study finds

New insight into impact of SARS-CoV-2 mutations on receptor binding

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

Clarity on covid count: Pandemic’s toll on seniors extended well beyond nursing homes

Dialysis patients' response to COVID19 vaccine type

COVID-19 vaccination offers significant protection for solid organ transplant recipients

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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