Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Over a third of people in UK and US will be obese by 2025

A recent analysis of body mass index (BMI) around the world has revealed a startling increase in the prevalence of obesity. The number of obese people worldwide increased from 105 million in 1975 to 641 million in 2014.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) offers a new tool for scientists working to better understand this disease and research new therapeutic targets.

31 Mar 2016

Pediatric surgeons who perform very few procedures after graduation may have hard time in the long run

Some pediatric surgeons perform so few rare and complex procedures once they finish their surgical training that they may have a hard time maintaining operative skills in the long run, according to a new study led by researchers at Ann & Robert H. Lurie Children’s Hospital of Chicago.

31 Mar 2016

Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy aging

The average life expectancy in the United States is approximately 78 years old. Americans live longer, with better diets and improved health care, than ever before, but only 0.02 percent will hit the century mark.

30 Mar 2016

New report offers startling statistics about chronic kidney disease in the U.S.

A sweeping new report assessing chronic kidney disease in the United States offers startling statistics about a condition that affects almost 14 percent of the U.S. population and costs billions in Medicare spending each year.

30 Mar 2016

New thematic issue highlights link between hyperuricemia, gout and kidney disease

The increasing prevalence of both gout and chronic kidney disease has led to a growing interest in the association between hyperuricemia (an abnormally high level of uric acid in the blood) and kidney disease.

29 Mar 2016

Young people with Cushing syndrome may be at higher risk for suicide, depression

Children with Cushing syndrome may be at higher risk for suicide as well as for depression, anxiety and other mental health conditions long after their disease has been successfully treated, according to a study by researchers at the National Institutes of Health.

29 Mar 2016

Study identifies genetic differences in kidney tumors of African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

26 Mar 2016

Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

University of Alabama at Birmingham researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using the laser-scanning method called MALDI tissue imaging to localize the changes.

24 Mar 2016

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

The use of peripheral nerve blocks (PNBs) is associated with better medical and economic outcomes in patients receiving hip and knee replacement, according to research being presented at the 41st Annual Regional Anesthesiology and Acute Pain Medicine Meeting later this month.

24 Mar 2016

Children with cardiomyopathy may benefit from family-linked treatment

A newly published national study by the Children's Hospital of Michigan and Wayne State University School of Medicine researchers shows that "parental impact and family functioning" become increasingly abnormal when children with cardiomyopathy-related chronic heart disease are more severely ill than children less affected by the disease.

24 Mar 2016

Endocrine Society issues recommendations to improve care for people with diabetes

To provide integrated care for people who have diabetes and may be at risk of developing related medical complications, the U.S. health care system needs to continue building effective multidisciplinary care team models, according to new recommendations issued by the Endocrine Society today.

23 Mar 2016

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

New research indicates that mycophenolate mofetil, a drug that is usually used to prevent rejection after kidney, heart or liver transplant, seems safe and effective in treating autoimmune hepatitis (AIH), a serious chronic liver disease that mainly affects women.

22 Mar 2016

Cell biologists identify new way for curing cancer and vessel diseases

Cell biologists from the Lomonosov Moscow State University discovered a new way of regulating of cell motility -- this discovery will make possible development of new drugs for curing onco- and vessel diseases.

22 Mar 2016

Doctors now have better tool to assess individual kidney function

Doctors now have a much-improved tool to assess individual kidney function, thanks to the work of an international team led by University of Saskatchewan medical imaging specialists Drs. Carl and Michal Wesolowski.

21 Mar 2016

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

21 Mar 2016

Six1 gene may have more substantial role in human kidney development

The best laid plans of mice and men are a bit different -- at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans may owe these abundant nephrons to a gene called SIX1, according to a new paper published in the journal Development.

21 Mar 2016

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

19 Mar 2016

Nephrology News and Research

Further Reading

Over a third of people in UK and US will be obese by 2025

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

Pediatric surgeons who perform very few procedures after graduation may have hard time in the long run

Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy aging

New report offers startling statistics about chronic kidney disease in the U.S.

New thematic issue highlights link between hyperuricemia, gout and kidney disease

Young people with Cushing syndrome may be at higher risk for suicide, depression

Study identifies genetic differences in kidney tumors of African-Americans

Wnt secretion inhibitors may reduce renal fibrosis

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

Children with cardiomyopathy may benefit from family-linked treatment

Endocrine Society issues recommendations to improve care for people with diabetes

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

Cell biologists identify new way for curing cancer and vessel diseases

Doctors now have better tool to assess individual kidney function

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Six1 gene may have more substantial role in human kidney development

Manipulation of NAD could lead to potential therapy for acute kidney injury

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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