in vivo News and Research

RSS

arGEN-X and Shire achieve milestone in SIMPLE Antibody R&D collaboration

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has attained a key success milestone in its SIMPLE Antibody research and product development collaboration with the Human Genetic Therapies division of Shire Pharmaceuticals. The milestone, which triggered an undisclosed payment from Shire, was the first demonstration of in vivo proof of concept for one of the antibody discovery programs undertaken in the collaboration.

19 Sep 2013

New optical imaging tool enables scientists to observe tumors and uncover inner workings

Scientists seeking new ways to fight cancer often try to understand the subtle, often invisible, changes to DNA, proteins, cells, and tissue that alter the body's normal biology and cause disease.

18 Sep 2013

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

SignaBlok, Inc., a Massachusetts-based biopharmaceutical company, today announced the successful in vivo proof of concept data that demonstrate that the company's novel mechanism-based, first-in-class peptide inhibitor of TREM-1 effectively suppresses cancer progression in mouse models of lung cancer and dramatically improves survival in septic mice.

18 Sep 2013

Functional brain mapping and high speed physiology multiphoton system from Olympus

The Olympus FluoView® FVMPE-RS, a dedicated multiphoton microscope system, enables high-precision, ultra-fast scanning and stimulation, allowing researchers to see deep within specimens, take measurements at the highest speeds, and capture images even when working under the most demanding conditions.

From Evident Corporation - Life Sciences 17 Sep 2013

Prairie Technologies acquired by Bruker

Bruker Corporation today announced that it has acquired Prairie Technologies, Inc. (Prairie), a provider of life science fluorescence microscopy products. The acquisition strengthens Bruker’s position in life science markets, adding to the Bruker Nano Surfaces Division’s existing life science atomic force microscopy (Bio-AFM) systems.

From Bruker Nano Surfaces and Metrology 13 Sep 2013

CardioExcyte 96 for cardiac toxicity profiling and screening introduced by Nanion

Cardiac safety assessment is a vital part of drug development since late withdrawals of compound candidates, due to heart liability issues such as ventricular arrhythmia, are very costly. In-vivo methods give highly relevant information but are extremely low throughput allowing the analysis of only a handful of compounds.

From Nanion Technologies 13 Sep 2013

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

The ability to visualize and analyze the spread of viral infections in primary and metastatic tumors is an essential component in characterizing the therapeutic efficacy of oncolytic viruses.

12 Sep 2013

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Whether it's the Ebola virus or Sarin and Ricin, a key to responding to chemical or biological attacks is having effective antidotes at the ready. To accelerate the development of new therapies, Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is leading a unique $24 million federally funded project to develop a "body on a chip" that will be used to develop these countermeasures.

12 Sep 2013

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces it has successfully generated potent antibody antagonists of Nav1.7, using its proprietary SIMPLE Antibody™ technology.

12 Sep 2013

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life. Scientists may now know why. A collaborative study, in which Berkeley Lab researchers played a pivotal role, points to increased stem cell self-renewal and subsequent mammary stem cell enrichment as the culprits.

12 Sep 2013

North Carolina professor receives 2013 New Scholar in Aging Award from Ellison Medical Foundation

Li Qian, PhD, an assistant professor in the University of North Carolina School of Medicine, has received a 2013 New Scholar in Aging Award from the Ellison Medical Foundation.

12 Sep 2013

Umbilical cord mesenchymal stem cells may have targeting capacity for glioma

Glioblastoma is the most common ma-lignant primary brain tumor in adults. The aggressive growth manner, characterized by marked angiogenesis and extensive tumor cell invasion into normal brain parenchyma with frequent formation of tumor microsatellites at distal sites, makes eradication impossible even after extensive microsurgical resection combined with current standard chemoradiation and adjuvant temozolomide.

11 Sep 2013

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

By binding multiple molecules of a common leukemia drug with nanodiamonds, scientists from the National University of Singapore (NUS) and University of California, Los Angeles (UCLA) managed to boost the delivery of the drug to leukemic cells and retain the drug within the cells to combat the cancer.

11 Sep 2013

Chemists Find New Way To Put The Brakes On Cancer

...

10 Sep 2013

Researchers find key mechanism behind Alzheimer's disease

Alzheimer's disease affects more than 26 million people worldwide. It is predicted to skyrocket as boomers age-nearly 106 million people are projected to have the disease by 2050.

7 Sep 2013

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

It is widely believed that bone marrow mesenchymal stem cells are highly adherent fibroblastic cells, defined as colony-forming unit-fibroblasts. Nevertheless, a few reports have shown that the non-adherent bone marrow cells can give rise to colony-forming unit-fibroblasts in vitro, and possess a certain differentiation potential.

6 Sep 2013

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Unravelling the mechanisms of cardiac fibrosis will lead to the discovery of therapeutic target candidates for various cardiac diseases. FIBRO-TARGETS brings together eleven European expert teams from six different countries both from public research institutes and European biotechs.

5 Sep 2013

New laser-based tool could improve accuracy of brain tumor surgery

In the battle against brain cancer, doctors now have a new weapon -- a new imaging technology that will make brain surgery dramatically more accurate by allowing surgeons to distinguish -- at a microscopic level -- between brain tissue and tumors.

5 Sep 2013

Taconic To Promote And Sell Medicyte Hepatocyte Products

...

4 Sep 2013

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

in vivo News and Research

arGEN-X and Shire achieve milestone in SIMPLE Antibody R&D collaboration

New optical imaging tool enables scientists to observe tumors and uncover inner workings

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

Functional brain mapping and high speed physiology multiphoton system from Olympus

Prairie Technologies acquired by Bruker

CardioExcyte 96 for cardiac toxicity profiling and screening introduced by Nanion

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

arGEN-X generates potent antibody antagonists of Nav1.7 using SIMPLE Antibody technology

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

North Carolina professor receives 2013 New Scholar in Aging Award from Ellison Medical Foundation

Umbilical cord mesenchymal stem cells may have targeting capacity for glioma

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

Chemists Find New Way To Put The Brakes On Cancer

Researchers find key mechanism behind Alzheimer's disease

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

New laser-based tool could improve accuracy of brain tumor surgery

Taconic To Promote And Sell Medicyte Hepatocyte Products

Researchers develop new opioid drug for chronic pain

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News