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Targeting a protein could be key to suppressing breast cancer metastasis

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis.

5 Feb 2020

Study underscores the need for more precise rare disease definitions

Some diseases are like black swans. They occur so rarely that many physicians never encounter them in their clinical practice, complicating efforts to treat them.

5 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Research highlights the benefits of physical activity for older adults

Physically active older adults benefit from reduced risks of early death, breast and prostate cancer, fractures, recurrent falls, functional limitations, cognitive decline, dementia, Alzheimer's disease, and depression.

5 Feb 2020

Study sheds new light on genetic relationship between three mood disorders

Researchers shed new light on the genetic relationship between three mood disorders associated with depression--major depression and bipolar disorder types 1 and 2, in a new study in the journal Biological Psychiatry, published by Elsevier.

5 Feb 2020

Good rehab is hard to find

Pattie Vargas saw with frightening clarity that her son Joel, 25 at the time, had a life-threatening drug problem. He came home one day in 2007 "high as a kite," went to bed and slept four days straight, Vargas, now a 65-year-old resident of Vacaville, California, recalls.

5 Feb 2020

Population‐level study of older adults identifies risk factors for cognitive decline

In older adults with abdominal obesity (excess belly fat), sustained elevations of blood sugar were linked to a higher likelihood of experiencing cognitive decline. In older adults without abdominal obesity, the hormone adiponectin appeared to be a likely risk factor for cognitive decline.

5 Feb 2020

Self‐perception of aging may impact older cancer patients' mortality risk

Self-perception of aging--or attitudes toward one's aging experience--may affect older individuals' risk of dying early after being diagnosed with cancer, according to results from a study published in Cancer Medicine.

5 Feb 2020

Smart insulin-delivery patch could monitor and manage glucose levels in people with diabetes

UCLA bioengineers and colleagues at UNC School of Medicine and MIT have further developed a smart insulin-delivery patch that could one day monitor and manage glucose levels in people with diabetes and deliver the necessary insulin dosage.

5 Feb 2020

Heart muscle cells of zebrafish change their metabolism during heart regeneration

Researchers from the group of Jeroen Bakkers at the Hubrecht Institute have found that the muscle cells in the heart of zebrafish change their metabolism, the way in which they generate energy, during heart regeneration.

5 Feb 2020

Novel hydrogels degrade while stem cells flourish for tissue repair

Baby diapers, contact lenses and gelatin dessert. While seemingly unrelated, these items have one thing in common -- they're made of highly absorbent substances called hydrogels that have versatile applications.

4 Feb 2020

New treatment target for acute kidney injury prevention revealed

Up to 10% of patients who are hospitalized or undergo surgery will experience acute kidney injury, and as many as 50% of patients in intensive care units will meet the criteria for AKI, the National Kidney Foundation has determined. Some of these patients will progress to kidney failure within months.

4 Feb 2020

Neighborhood characteristics linked with women's use of preventive care

A study conducted by Columbia University School of Nursing shows where a woman lives influences her use of preventive health care more than her income or race/ethnicity or whether she is depressed.

4 Feb 2020

Burden of early-onset colorectal cancer incidence has been underestimated, study shows

A study analyzing LSU Health's Louisiana Tumor Registry and other NCI-designated tumor registry data found that by the time recommended screening for colorectal begins, cancers have already spread in a high percentage of people.

4 Feb 2020

Study provides key insights into pregnant women's use of marijuana

As the use of marijuana is legalized in an increasing number of U.S. states, the number of people who use the drug daily is on the rise. This upward trend also holds up in women who are pregnant or breastfeeding, despite evidence that using marijuana could harm their babies.

4 Feb 2020

Roughly half of opioid prescriptions by dentists exceed pain-management guidelines

A new study suggests that roughly half of the opioid prescriptions written by dentists in the United States exceed the three-day supply recommended by federal dental pain-management guidelines.

4 Feb 2020

Public speakers often mistaken about efficacy of drugs due to conflicts of interest

Researchers from the United States have found that public may be under a mistaken belief regarding the efficacy of commercially available drugs and drug promotions and bias may be the reason behind this.

4 Feb 2020

Study: Medicaid expansion reduced uninsured rates in diabetes belt

Medicaid expansion dramatically reduced the numbers of low-income residents without insurance in the Diabetes Belt, a swath of 644 counties across 15 southeastern states (including Virginia) that are stricken with high diabetes rates, a new study has found.

4 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020