Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

In a new study, a team of researchers used cryo-electron microscopy to determine the spike (S) structures of the SARS-CoV-2 Omicron variant to understand how the mutations that alter its primary sequence impact S conformation.

1 Feb 2022

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

In a new study, researchers reported the first evidence of natural SARS-CoV-2 infections among domestic rabbits in France.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Study shows mRNA booster dose eliminates immune escape observed with SARS-CoV-2 Omicron

Researchers examined total and neutralizing antibodies to the spike protein of SARS-CoV-2, and neutralizing antibodies against Washington-1 (WA-1) and variants of concern (VOC) including Beta, Delta, and Omicron in a longitudinal cohort.

31 Jan 2022

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

A new study has assessed the antibody responses to the mRNA-1273 Moderna vaccine over time.

31 Jan 2022

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

A new study posted to the medRxiv* preprint server has evaluated the effect of mRNA-based COVID-19 vaccination and boosting strategy on serum antibody responses in PAD patients against the original SARS-CoV-2 strain and circulating variants.

31 Jan 2022

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Researchers from Moderna, the developers of one key vaccine, have been investigating its ability to protect against the Omicron variant.

31 Jan 2022

Response to COVID-19 vaccine booster in seronegative kidney transplant recipients

Modification of vaccination strategies is needed to improve the immune response to SARS-CoV-2 vaccination in kidney transplant recipients (KTRs).

31 Jan 2022

Study finds limited evidence for IL-1 blockers in treating COVID-19

Researchers assess the effectiveness and safety outcomes of interleukin-1 blocking agents in the treatment of COVID-19.

31 Jan 2022

Study assesses the antibody response to additional dose of COVID-19 vaccine in transplant recipients

A study has begun to assess the antibody response to an additional dose of a COVID-19 mRNA vaccine in kidney and liver transplant recipients, either alone or with a concurrent reduction in immunosuppressive medication.

31 Jan 2022

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

In a new study, scientists revealed that three consecutive exposures SARS-CoV-2 spike protein through infection, vaccination, or both can induce strong neutralizing antibodies against a wide variety of viral variants, including omicron.

31 Jan 2022

Researchers create model to predict COVID-19 mortality

In a new study, researchers have created a model that can help determine the outcome of COVID-19 infection in patients in the ICU.

31 Jan 2022

Evaluating clinical outcomes and viral loads of SARS-CoV-2 Delta and Omicron infections

The current study showed a marked decrease in disease severity with Omicron compared to the Delta variant.

31 Jan 2022

Nucleocapsid antigen found to be a sensitive biomarker for acute COVID-19 infection

In a new study, researchers found that nucleocapsid antigen in the blood (antigenemia) is a sensitive and specific biomarker for acute coronavirus disease 2019 infection.

31 Jan 2022

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

A new study by Norwegian researchers suggests that vaccine-induced immunological memory and the activation of recall responses in the body yields similar coverage for Omicron and Delta variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

31 Jan 2022

Antibody News and Research

Further Reading

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Study shows mRNA booster dose eliminates immune escape observed with SARS-CoV-2 Omicron

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Response to COVID-19 vaccine booster in seronegative kidney transplant recipients

Study finds limited evidence for IL-1 blockers in treating COVID-19

Study assesses the antibody response to additional dose of COVID-19 vaccine in transplant recipients

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

Researchers create model to predict COVID-19 mortality

Evaluating clinical outcomes and viral loads of SARS-CoV-2 Delta and Omicron infections

Nucleocapsid antigen found to be a sensitive biomarker for acute COVID-19 infection

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

Children and adolescents respond as well or better than adults to mRNA-1273 COVID vaccination

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Immunity based upon “mild" Omicron infection is weak for Omicron reinfection

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

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