Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability.

8 Oct 2019

Spatial Gene Expression Profiling of Neurological Disorders

In this interview, Cedric Uytingco discusses the key benefits of being able to visualize gene expression patterns in neurological samples.

From 10x Genomics, Inc. 7 Oct 2019

Researchers identify new targets to treat fibrotic diseases

When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term - but bad when myofibroblast activation gets out of hand.

4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

Findings shed light on molecular reasons for early miscarriage

Researchers at Karolinska Institutet in Sweden have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells.

3 Oct 2019

New project to examine roles of microgravity and cosmic radiation in tumor growth, development

Can weightlessness stop cancer from growing? One of the nine research projects that has been given the go-ahead for the new China Space Station scheduled for 2022 is designed to answer this exact question.

3 Oct 2019

Novel viral vector improves gene therapy for sickle cell disease

Researchers at the National Institutes of Health (NIH) have developed a unique, improved lentiviral vector for use in gene therapy for sickle cell disease.

3 Oct 2019

Researchers elucidate enzymes that control long-term memory, learning process in the brain

When we first purchase a smart phone, all of our settings and applications are the same. But as time passes, everyone's phones will change drastically as we adapt them to our own individual needs and preferences. In the same way, our memories and life experiences are loaded into our brains, making one person unique from another.

2 Oct 2019

Researchers make breakthrough in gene therapy for sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector--a virus-based vehicle that delivers therapeutic genes--for use in gene therapy for sickle cell disease.

2 Oct 2019

Researchers observe the effects of two proteins responsible for metastasis

The research by Assoc. Prof. Nurhan özlü of Koç University Department of Molecular Biology and Genetics and her team recently published in Molecular & Cellular Proteomics has observed the effects of two proteins in the transition from the epithelial to the mesenchymal cell type, the latter of which has mobility.

2 Oct 2019

Using AI to transform drug discovery in a big way

According to the National Cancer Institute, approximately 38 percent of men and women will be diagnosed with cancer at some point in their lives.

1 Oct 2019

New $1.5 million grant could help develop innovative methods to halt spread of cancer

One of the most devastating pieces of news a cancer patient can receive is that their cancer has spread to other parts of the body.

1 Oct 2019

New study helps better understand how type 2 diabetes progresses as a disease

Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes.

1 Oct 2019

Wistar researcher receives NIH Director's Award to study link between diet, alcohol use and cancer

The National Institutes of Health today announced that Zachary T. Schug, Ph.D., assistant professor in the Molecular & Cellular Oncogenesis Program at The Wistar Institute, was awarded the prestigious NIH Director's New Innovator Award in support of his research on the link between a high sugar/fat diet, alcohol use and cancer.

1 Oct 2019

New method can help detect melanoma cells in skin tumors

Melanoma is the least common but one of the most deadly skin cancers. It accounts for only about one percent of all cases globally, but the majority of skin cancer deaths.

30 Sep 2019

Lifelong choline supplementation holds potential to prevent Alzheimer's disease

In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease.

27 Sep 2019

Human aging processes may hinder cancer development, study finds

A new study, published in Aging Cell, has found that human aging processes may hinder cancer development.

27 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Study may help scientists to learn more about the causes of chronic pain

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal - but not physical- sensations in mice.

27 Sep 2019

Temporal fluctuations in protein concentrations can determine fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount of certain proteins play a direct and significant role on biological processes.

26 Sep 2019