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Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Immunotherapy in combination with chemotherapy has become an important therapeutic treatment option in some patients with metastatic breast cancer.

14 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Study finds tree nuts as snack alternative boost metabolic health in young adults

Study found that replacing typical carbohydrate snacks with tree nuts in young adults' diets for 16 weeks improves metabolic health, with females showing reduced waist circumference and lipid biomarkers, and males enhanced insulin sensitivity, without other dietary changes.

11 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

LysoPI lipids show promise in boosting insulin secretion in diabetics

While sugar is the most frequently named culprit in the development of type 2 diabetes, a better understanding of the role of fats is also essential.

4 Dec 2023

New study shows Spirulina and high-intensity training combo reduces obesity complications in men

The effects of combining high-intensity interval training (HIIT) with spirulina supplements to mitigate cardiometabolic disease risk.

27 Nov 2023

High dietary insulin index associated with increased risk of metabolic unhealthiness, research show

Study explored the association between dietary insulin index (DII) and dietary insulin load (DIL) with metabolic healthy (MH) status and the serum levels of brain-derived neurotrophic factor (BDNF) and adropin among the Iranian adult population.

24 Nov 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Higher amounts of visceral abdominal fat in midlife may increase Alzheimer's disease risk

Higher amounts of visceral abdominal fat in midlife are linked to the development of Alzheimer's disease, according to research being presented next week at the annual meeting of the Radiological Society of North America.

20 Nov 2023

New insights into the pathogenesis of chronic liver diseases

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and alcoholic-associated liver disease (ALD). NAFLD is associated with obesity, insulin resistance, and metabolic syndrome, while ALD is caused by excessive alcohol consumption.

7 Nov 2023

UTHSC researcher part of team studying obesity-cancer connection

A University of Tennessee Health Science Center (UTHSC) researcher is a member of a prestigious team that has just received a highly competitive Endeavor Award totaling $3 million from The Mark Foundation for Cancer Research.

26 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

Mapping the mysteries: Study reveals surprising hubs of human immune cells

Researchers in Israel comprehensively mapped the distribution and mass of primary immune cells across human tissues. This groundbreaking study, using advanced biotechnological methods, provides insights into the immune system's cellular network, challenging existing notions and emphasizing the bone marrow, lymph nodes, and spleen as primary immune cell reservoirs.

24 Oct 2023

CT-measured VAT volume key in assessing diabetes risk in prediabetic individuals

Whether visceral obesity assessment in individuals with prediabetes could help predict the future risk of developing diabetes.

24 Oct 2023

Hormone levels tied to metabolic health in obesity

Researchers investigate the relationship between obesity types and serum leptin (LEP) and adiponectin (ADP) levels, shedding light on metabolic differences in various obesity phenotypes. Their findings highlight correlations between adipokines, glucose utilization, lipid metabolism, and obesity-related metabolic disorders.

22 Oct 2023

How African sleeping sickness melts away body fat: New study sheds light on the role of lipolysis

Researchers find that the T. brucei parasite, responsible for African trypanosomiasis, triggers weight loss by disrupting fat cell lipolysis. The study shows that ATGL enzyme is key to this process, potentially offering a new angle for future research and treatment.

17 Oct 2023

New study finds host strategy to cope with sleeping sickness

A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology found a new strategy by the host to cope with Trypanosoma brucei infection.

12 Oct 2023

Presidential advisory by the American Heart Association: connecting cardiovascular, kidney, and metabolic health

The interplay among chronic kidney disease, metabolic risk factors, and the cardiovascular system.

11 Oct 2023