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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Researchers conducted a detailed epitope mapping of Np and developed an experimental double antigen-based ELISA.

13 Jan 2022

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Researchers screen several systemic autoantibodies to assess their association with the severity of COVID-19.

13 Jan 2022

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

In the present study, researchers isolated an infectious AY.4.2 strain of COVID-19 from the nasopharyngeal swab of a symptomatic individual from the Paris region. Then, they introduced the AY.4.2 signature mutations - T95I, Y145H, and A222V - in an expression plasmid coding the Delta protein to study the function of the AY.4.2 S protein.

13 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Memory B cells never forget recurrent viral exposures and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is no exception, according to a new medRxiv* preprint study.

5 Jan 2022

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Now in new research, scientists from the University of Leicester have been investigating how these mutations alter the affinities of RBDs to ACE2.

28 Dec 2021

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests.

24 Dec 2021

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

A new study shows that although the Omicron variant exhibits significant immune escape compared to other SARS-CoV-2 variants, antibody neutralization can be largely restored with booster doses of mRNA vaccines.

22 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers discuss the sensitivity of the SARS-CoV-2 Omicron variant towards various monoclonal antibodies.

20 Dec 2021

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Researchers demonstrated the unexpected roles of nucleocapsid protein in innate and adaptive immunity to SARS-CoV-2.

15 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Researchers from Sorbonne Universite have been investigating the effect of the BNT162b2 mRNA vaccine on HIV-positive individuals.

9 Dec 2021

Flow Cytometry News and Research

Further Reading

Specific immunoresponse to SARS-CoV-2 in cats and dogs housed with COVID-19 patients

Assessing how autoantibodies in COVID-19 correlate with anti-viral humoral responses

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

Researchers investigate SARS-CoV-2 specific inflammatory response

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

Defensosomes can act as decoys to protect against SARS-CoV-2

Molecular mechanism of SARS-Cov-2-induced thrombosis

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

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