Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

In a Phase 1 clinical study, researchers led by EPFL and their partners report that a new liver- and gut-targeted oral drug can safely lower triglycerides and other blood lipids.

16 Jan 2026

Study reveals genetic signatures linked to HIV-related cognitive impairment

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

14 Jan 2026

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer's disease.

13 Jan 2026

Dietary protein reshapes how cholera bacteria colonize the gut

Researchers investigate the role of dietary components and the gut microbiota in cholera.

13 Jan 2026

Gene regulators could restore the aging body's ability to self-repair

As we age, we don't recover from injury or illness like we did when we were young. But new research from UCSF has found gene regulators - proteins that turn genes on and off - that could restore the aging body's ability to self-repair.

12 Jan 2026

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Smoking tobacco is known to worsen symptoms of periodontitis and reduce responsiveness to treatment. Using high-resolution spatial transcriptomics, researchers identified differences between smokers and non-smokers in the expression of genes that weaken gum epithelial integrity and cause bone damage through inflammation.

12 Jan 2026

Weight loss normalizes fat tissue at cellular level

It is well known that obesity typically leads to inflammation and dysfunction of fat tissue that increases the risk of developing metabolic diseases such as diabetes and cardiovascular diseases.

12 Jan 2026

ALS breakthrough: Restoring protein production in motor neuron axons

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

12 Jan 2026

Earthworm-based composting offers a low-energy solution to antibiotic resistance

Earthworms could become unexpected allies in the global fight against antibiotic resistance, by helping farmers turn manure into safer, high-value organic fertilizer through a process called vermicomposting.

9 Jan 2026

Scientists discover how stem cells navigate and repair brain damage after stroke

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye-called the cornea-can heal from minor scratches within a single day.

8 Jan 2026

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

The study reveals that environmental stressors do not merely kill bacteria; they can also prime surviving cells to take up resistance genes more efficiently, raising concerns about how antibiotic-resistant bacteria may spread in aquatic environments.

8 Jan 2026

Natural daylight during office hours improves glucose stability in type 2 diabetes

Natural daylight exposure during office hours improves glucose control and boosts fat oxidation in individuals with type 2 diabetes, enhancing metabolic health.

8 Jan 2026

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastoma

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor.

7 Jan 2026

Understanding the impact of pregnancy stressors on neuroimmune landscape of the fetal brain

The maternal microbiome and immune system have both independent and synergistic effects on fetal brain health - changes in the mother's immune system have been linked to an increased risk of neurodevelopmental disorders in children.

6 Jan 2026

Repurposed drug combination shows strong promise against liver fibrosis

The study shows that this drug pair works far better together than either agent alone, offering a realistic and potentially fast path toward a new antifibrotic therapy.

6 Jan 2026

Vitamin A derivative suppresses immune response and cancer vaccine efficacy

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

5 Jan 2026

Jumping genes reshape cancer genomes through 3D chromatin interactions

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

5 Jan 2026

Gut microbes shown to directly shape brain function and evolution

A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works.

5 Jan 2026

RNA splicing and processing genes emerge as central drivers of aging across tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

5 Jan 2026

Two bacterial shutdown modes explain antibiotic persistence and relapse

New study reveals that bacteria can survive antibiotic treatment through two fundamentally different "shutdown modes," not just the classic idea of dormancy.

4 Jan 2026

Gene Expression News and Research

Further Reading

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

Study reveals genetic signatures linked to HIV-related cognitive impairment

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

Dietary protein reshapes how cholera bacteria colonize the gut

Gene regulators could restore the aging body's ability to self-repair

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Weight loss normalizes fat tissue at cellular level

ALS breakthrough: Restoring protein production in motor neuron axons

Earthworm-based composting offers a low-energy solution to antibiotic resistance

Scientists discover how stem cells navigate and repair brain damage after stroke

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

Natural daylight during office hours improves glucose stability in type 2 diabetes

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastoma

Understanding the impact of pregnancy stressors on neuroimmune landscape of the fetal brain

Repurposed drug combination shows strong promise against liver fibrosis

Vitamin A derivative suppresses immune response and cancer vaccine efficacy

Jumping genes reshape cancer genomes through 3D chromatin interactions

Gut microbes shown to directly shape brain function and evolution

RNA splicing and processing genes emerge as central drivers of aging across tissues

Two bacterial shutdown modes explain antibiotic persistence and relapse

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