Infectious Diseases News and Research

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High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study from the University of Gothenburg.

9 Dec 2025

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

SARS‑CoV‑2, the virus that causes COVID-19, continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid.

8 Dec 2025

Targeted approach of immunotherapy improves sepsis outcomes

Immunotherapy for sepsis is effective when doctors tailor the treatment precisely to the patient's immune system condition.

8 Dec 2025

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level.

5 Dec 2025

Long-acting HIV treatment could improve outcomes for breastfeeding women

Sujata Tewari, BA, previously of the Medical Practice Evaluation Center (MPEC) at Massachusetts General Hospital, and Andrea L. Ciaranello, MD, MPH, of the MPEC and Department of Medicine at Massachusetts General Hospital, are the lead and senior authors of a paper published in the Journal of Infectious Diseases, “Long-acting antiretroviral therapy for breastfeeding women with HIV experiencing barriers to adherence in Zimbabwe: Modeling clinical impact and cost-effectiveness.

4 Dec 2025

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon, say disease specialists.

4 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

New analysis reveals fundamental flaws in widely used measures of biological aging

A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and conceptualizes biological aging.

3 Dec 2025

Americans trust AMA over CDC on vaccine safety

For decades, health-related statements by major professional health associations such as the American Medical Association (AMA) agreed with those of the Centers for Disease Control and Prevention (CDC) because both relied on the same body of scientific knowledge, much of it funded by the federal health sector.

3 Dec 2025

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

An updated Cochrane review has found that calcium supplementation has no effect on pre-eclampsia, challenging long-held assumptions about the role of calcium in preventing hypertensive disorders in pregnancy.

3 Dec 2025

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia.

2 Dec 2025

WHO releases first guideline on the use of GLP-1 therapies for treating obesity

To address the growing global health challenge of obesity, which affects more than 1 billion people, the World Health Organization (WHO) has released its first guideline on the use of Glucagon-Like Peptide-1 (GLP-1) therapies for treating obesity as a chronic, relapsing disease.

2 Dec 2025

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Working out of a tribal-owned hospital in Anchorage, Alaska, liver specialist Brian McMahon has spent decades treating the long shadow of hepatitis B. Before a vaccine became available in the 1980s, he saw the virus claim young lives in western Alaskan communities with stunning speed.

2 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Mapping SV2A drug binding offers a path to better epilepsy treatments

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.

1 Dec 2025

Latent antimicrobial resistance found to be more widespread across the world

A team of researchers has discovered that latent antimicrobial resistance is more widespread across the world than known resistance.

1 Dec 2025

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment - an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.

1 Dec 2025

Updated Canadian guideline aims to raise awareness of new HIV prevention strategies

Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250511 contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these safe and effective options to teen and adult patients.

1 Dec 2025

Rapid point-of-care test shows promise for detecting latent tuberculosis

A new test shows promising results for detecting latent tuberculosis infection in resource-limited settings. This is according to a study from Karolinska Institutet, published in the journal Clinical Infectious Diseases.

27 Nov 2025

Global study reveals widespread latent antimicrobial resistance in wastewater

A team of researchers has discovered that latent antimicrobial resistance is more widespread across the world than known resistance.

27 Nov 2025

Infectious Diseases News and Research

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

Older chemical libraries yield new leads for next-generation COVID-19 antivirals

Targeted approach of immunotherapy improves sepsis outcomes

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

Long-acting HIV treatment could improve outcomes for breastfeeding women

Single-dose dengue vaccine will benefit populations in hard-to-reach regions

New rapid test distinguishes real HIV infections from vaccine-related false positives

New analysis reveals fundamental flaws in widely used measures of biological aging

Americans trust AMA over CDC on vaccine safety

Calcium fails to prevent pre-eclampsia in pregnant women, study finds

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

WHO releases first guideline on the use of GLP-1 therapies for treating obesity

RFK Jr. wants to delay the hepatitis B vaccine. Here’s what parents need to know.

Innate immunity and metabolic stress drive a unique form of cell death

Mapping SV2A drug binding offers a path to better epilepsy treatments

Latent antimicrobial resistance found to be more widespread across the world

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

Updated Canadian guideline aims to raise awareness of new HIV prevention strategies

Rapid point-of-care test shows promise for detecting latent tuberculosis

Global study reveals widespread latent antimicrobial resistance in wastewater

eBook: Advancing infectious disease vaccine development eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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