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Sodium channels play important role in keeping tiny lung capillaries from leaking, worsening pneumonia

Sodium channels in the cells that line the tiny capillaries in our lungs play an important role in keeping those capillaries from leaking and potentially worsening conditions like pneumonia, scientists report.

6 Sep 2017

Scientists use magnetic nanoparticles to trigger activity deep inside the brain

Scientists have used magnetism to activate tiny groups of cells in the brain, inducing bodily movements that include running, rotating and losing control of the extremities -- an achievement that could lead to advances in studying and treating neurological disease.

17 Aug 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Discovery of ‘protective shield’ for b-cells could provide new option for treating diabetes

The islets of Langerhans in the human pancreas produce and release insulin to regulate blood glucose levels. Insulin, which is specifically produced in b-cells, serves to prompt cells to take up glucose circulating in blood.

21 Jun 2017

IBS researchers devise nanochannels for iodide transport in cell membranes

Exchange of iodide (iodine ions) between bloodstream and cells is crucial for the health of several organs and its malfunctioning is linked to goiter, hypo- and hyperthyroidism, breast cancer, and gastric cancer.

8 Jun 2017

Salk scientist uses mathematical framework to better understand how cell types divide work

Despite advances in neuroscience, the brain is still very much a black box--no one even knows how many different types of neurons exist.

7 Jun 2017

Scientists discover unexpected mechanism behind chronic nerve pain

It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain.

1 Jun 2017

Supercomputer study of the brain could lead to safer and more effective anesthetics

Researchers have used a supercomputer to show how proteins in the brain control electrical signals, in a breakthrough that could lead to safer and more effective drugs and anesthetics.

22 May 2017

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Scientists have shown how diesel fumes trigger respiratory reflexes which could potentially worsen underlying conditions, such as asthma.

22 May 2017

Scientists discover new cause of dangerous cardiac instabilities

Sudden cardiac death resulting from fibrillation – erratic heartbeat due to electrical instability – is one of the leading causes of death in the United States.

3 May 2017

RCSI researchers discover that function of KCNQ1 gene is linked to survival of colon cancer patients

Researchers from RCSI (Royal College of Surgeons in Ireland) and the University of Nice, France, have discovered the function of a gene called KCNQ1 that is directly related to the survival of colon cancer patients.

21 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

New nanowire technology may serve as platform to screen drugs for neurological diseases

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail.

11 Apr 2017

New research uncovers how brain's capillary network controls blood flow, monitors neuronal activity

All it takes is the flip of a protein "switch" within the tiny wire-like capillaries of the brain to increase the blood flow that ensures optimal brain function.

25 Mar 2017

Advances in Optogenetics

Optogenetics is a way of introducing information into the brain using light, it targets specific cells or connections across the brain. It is fast, like brain signaling, and helps you communicate with neural circuitry in a language more similar to what is normally used within the brain.

From Pittcon 2 Mar 2017

Researchers unlock specific mechanisms behind Aβ-induced cytoxicity in Alzheimer's disease

Alzheimer's disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. A person with Alzheimer's disease suffers loss of control over thought, memory and language abilities.

14 Feb 2017

Malaria mosquitoes exhibit similar sensitivity to heat and horseradish

Researchers at Lund University in Sweden have taken an important step on the road to understanding the underlying mechanism of how and why animals can feel pain in connection with cold or heat. However, according to the study, temperature is just one triggering factor – horseradish, mustard, cinnamon and wasabi have a similar effect.

10 Feb 2017

Researchers identify ion channel required for proper regulation of basal metabolism and body weight

UT Southwestern Medical Center researchers have identified an ion channel required for brain cells to suppress eating behavior in response to the hormone leptin or to the anti-obesity drug lorcaserin.

7 Feb 2017

Nanion Technologies introduces new instrument for screening of membrane transporters and pumps

Nanion Technologies is pleased to announce the launch of the new SURFE2R 96SE Instrument for high throughput measurements of electrogenic membrane transporters and pumps.

From Nanion Technologies 3 Feb 2017

Integration of Genedata Screener with Nanion SyncroPatch 384PE can take APC experiments to new level

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, today announced new automated patch clamp (APC) functionality in Genedata Screener for Ion Channel Screening and a Genedata Ready-to-Run integration with Nanion SyncroPatch 384PE.