Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Safety profile of centrifugation artificial liver support systems with RMA for liver failure patients

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems.

10 Apr 2025

England faces persistent rise in alcohol deaths

The persistent higher rate of alcohol deaths in England since the pandemic in 2020 is an "acute crisis" requiring urgent action from government, according to a new study led by researchers at UCL and the University of Sheffield.

10 Apr 2025

Gum disease linked to worsening liver health

There is growing recognition in medicine that what happens in one part of the body can ripple through others.

9 Apr 2025

AI boosts liver cancer detection by highlighting doubtful areas

A new editorial was published in Oncotarget, Volume 16, on April 4, 2025, titled "Deep learning-based uncertainty quantification for quality assurance in hepatobiliary imaging-based techniques."

8 Apr 2025

Survey shows increased awareness of alcohol’s cancer risks

Public awareness of the link between drinking alcohol and an elevated risk of cancer has grown since last fall, with more than half of Americans now saying that regularly consuming alcohol increases your chances of later developing cancer, according to a survey by the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

1 Apr 2025

Owlstone Medical secures investment from Cystic Fibrosis Foundation

Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that the Cystic Fibrosis Foundation has made an up to USD $2.3 million equity investment (circa £1.7 million) in Owlstone to develop a breath test for Pseudomonas aeruginosa (PA) detection in patients with cystic fibrosis (CF).

29 Mar 2025

Simple changes in eating habits could help fight obesity

Obesity is linked to numerous health complications, including diabetes, cardiovascular disease, and fatty liver disease.

25 Mar 2025

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Hepatitis B is a liver infection cause by the hepatitis B virus (HBV), and long-term hepatitis B infections that last longer than six months are considered "chronic".

24 Mar 2025

Fatty liver disease linked to higher mortality risk from many common diseases

A comprehensive study from Karolinska Institutet shows that people with fatty liver disease have almost twice the mortality rate of the general population.

24 Mar 2025

Sticking to Life’s Essential 8 slashes cancer risk, major study shows

Long-term adherence to the American Heart Association’s “Life’s Essential 8” lifestyle score significantly reduces the risk of overall and site-specific cancers. Stable high LE8 scores over four years were linked to notably lower risks of lung, breast, liver, and colorectal cancers in a large Chinese cohort study.

23 Mar 2025

£2.2 million grant supports clinical trials for liver dialysis device

Clinical trials to continue the development of a liver dialysis device to treat those with life-threatening liver disease have been funded by a grant awarded to UCL, the Royal Free Hospital and Yaqrit.

21 Mar 2025

CB1R inhibition shows promise in protecting gut barrier from alcohol damage

Heavy alcohol consumption is a leading cause of gastrointestinal diseases, with binge drinking linked to increased intestinal permeability-a condition commonly known as "leaky gut."

19 Mar 2025

Researchers move closer to a functional cure for chronic hepatitis B

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

17 Mar 2025

Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

14 Mar 2025

Maternal high-fat diets linked to liver stress in unborn babies

When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life.

14 Mar 2025

Social advantage reduces risk of age-related diseases and slows aging

People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

Nwd1 gene linked to liver dysfunction in metabolic disease

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Is red meat good or bad for you? Study explains how amino acids shape the answer

Researchers at Texas Tech University reviewed how red meat proteins and amino acids affect human health, weighing both benefits and risks. Their findings highlight that while red meat provides vital nutrients, overconsumption and poor preparation methods can increase disease risk.

10 Mar 2025