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Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

Towering 'body-swap' robot exposes the brain’s strategy for staying upright

What if a robot could show us how the brain keeps us balanced? UBC scientists built one – and their discovery could help shape new ways to reduce fall risk for millions of people.

27 Nov 2025

New imaging protocol captures mouse brain cell connections in precise detail

An international team of researchers led by the Francis Crick Institute, working with the Paul Scherrer Institute, have developed a new imaging protocol to capture mouse brain cell connections in precise detail.

27 Nov 2025

Researchers uncover key mechanism blocking nerve regeneration in diabetes

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve fibres do not regenerate sufficiently.

26 Nov 2025

Researchers uncover how a key transcription factor reads DNA in human cells

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

26 Nov 2025

White matter alterations connect coronary artery disease to cognitive decline

Individuals with coronary artery disease (CAD) - a constricting or blocking of blood vessels feeding the heart - face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood.

25 Nov 2025

Long-term calorie restriction can slow cellular markers of brain aging

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage.

25 Nov 2025

Gut nervous system controls intestinal barrier and allergy risk

An international research team led by scientists from Bern and Charité - Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.

25 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

Gut neurons control immunity attack or repair

Beneath the surface of your gut lies a vast network of neurons—as many as in your spinal cord. New research from the Champalimaud Foundation (CF) in Lisbon shows that in mice this "second brain" helps decide whether the immune system should go into attack mode or start repairing tissue.

24 Nov 2025

Intranasal nanomedicine shows promise against glioblastoma

Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers.

22 Nov 2025

Brain circuit identified as key to repetitive and compulsive behaviors in mice

Researchers at Karolinska Institutet in Sweden have identified a brain circuit that can drive repetitive and compulsive behaviors in mice, even when natural rewards such as food or social contact are available.

22 Nov 2025

Study clarifies how spermine can guard against Alzheimer’s and Parkinson’s

Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together.

21 Nov 2025

New neuron signaling mechanism reveals safer pathway for pain treatment

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead to safer, more effective treatments.

20 Nov 2025

Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

Ischemic stroke, a leading cause of disability and mortality worldwide, is a complex cerebrovascular event with outcomes heavily influenced by the inflammatory response.

20 Nov 2025

Scientists uncover molecular mechanism behind chemotherapy-induced peripheral neuropathy

Chemotherapy activates a stress sensor in immune cells, triggering inflammation and nerve damage, which may help explain why many cancer patients experience debilitating pain as a side effect, according to a new study by Weill Cornell Medicine and Wake Forest University School of Medicine researchers

20 Nov 2025

Study reveals how aging reshapes protein chemistry in the brain

A study by the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena shows that the chemical composition of proteins in the brain undergoes fundamental changes with aging.

20 Nov 2025

Clogged brain drains may signal early Alzheimer's risk

"Drains" in the brain, responsible for clearing toxic waste in the organ, tend to get clogged up in people who show signs of developing Alzheimer's disease, a study by researchers from Nanyang Technological University, Singapore (NTU Singapore) has discovered.

19 Nov 2025

Analysis reveals overutilization of imaging in Bell's palsy

This study analyzes how imaging is used to diagnose and manage Bell's palsy, a condition that causes sudden weakness in the muscles on one side of the face, usually temporarily.

14 Nov 2025

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025