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Major gaps found in cholesterol management for young adults

Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or "bad" cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's 2025 Scientific Sessions.

6 Nov 2025

Experimental intranasal vaccine triggers broad immune response against multiple strains of H5N1

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) reported encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 "bird flu".

6 Nov 2025

New combination treatment overcomes resistance in ER positive breast cancer

In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have tested a new combination therapy for hormone-resistant, estrogen receptor-positive (ER+) breast cancer and were able to shrink tumors, reduce the number of cancer stem cells and reprogram the immune environment to be less supportive of cancer growth.

6 Nov 2025

Newly identified microglia subtype offers protection against Alzheimer’s disease

In Alzheimer's disease, the leading cause of dementia, microglia-the brain's immune defenders-can act as both protectors and aggressors, shaping how the disease progresses.

5 Nov 2025

Galectin-3 found to drive crucial cell fusion in early placental development

During the first weeks of pregnancy, the developing placenta in a mother's womb undergoes a dramatic change.

5 Nov 2025

Top-five pharmaceutical company expands partnership with Aptamer for multi-target Optimer® development program

Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, today announced a new contract valued at up to £617,000 with a top-five pharmaceutical company.

4 Nov 2025

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed an innovative strategy to construct a series of biodegradable cesium nanosalts.

4 Nov 2025

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Women who consumed more ultra-processed foods (UPFs) showed distinct DNA methylation patterns, mostly reduced across key gene regions. These exploratory findings suggest that high UPF intake may influence gene regulation through epigenetic mechanisms.

4 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

NIH grant supports research on how the immune system responds to serious eye infections

New research that sheds light on how the immune system responds to serious eye infections is underway at Wayne State University, supported by a $2.3 million federal grant from the National Eye Institute of the National Institutes of Health (NIH).

3 Nov 2025

Scientists create detailed single-cell map of the developing human brain

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, and how they grow and interact.

3 Nov 2025

New $4.4 million grant funds first study of prefrontal cortical stimulation in severe bipolar disorder

A University of Minnesota Medical School research team, led by Ziad Nahas, MD, has been awarded a $4.4 million grant for a first-in-the-world study of prefrontal cortical stimulation in severe bipolar disorder.

31 Oct 2025

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

31 Oct 2025

Scripps Research scientists receive NIH grant to unlock long-term HIV protection

Nearly 40 years after HIV was first identified, the virus continues its devastating march across the globe. Today, 38 million people live with HIV, and each year brings 1.5 million new infections and 650,000 more deaths-while nearly 10 million people still lack access to life-saving medicines.

31 Oct 2025

New method enhances precision in bionic limb movement interpretation

Despite enormous progress in the past two decades, the intentional control of bionic prostheses remains a challenge and the subject of intensive research.

31 Oct 2025

Sensory effects of flavanols trigger physiological responses in the brain

Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols.

31 Oct 2025

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.

31 Oct 2025

19 NCAA women's college basketball coaches join hands to support women’s heart health

Both on the court and off, cardiovascular disease is the leading killer of women in the United States, taking the lives of more than 440,000 women each year, according to the American Heart Association, a relentless force changing the future of health for everyone everywhere.

30 Oct 2025

Advances in diagnosis and management of systemic light chain amyloidosis

Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to progressive structural and functional impairment.

30 Oct 2025

Global Virus Network announces the addition of three new Centers of Excellence

The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, today announced the addition of three new Centers of Excellence: the USF Health Institute for Translational Virology and Innovation at the University of South Florida (USF) in Tampa, Florida, USA, the Department of Microbiology, Immunology and Parasitology at the Federal University of São Paulo (UNIFESP) in Brazil, and the Pathogen Research Centre (PaRC) at Western University in Canada.

30 Oct 2025

Next Generation News and Research

Major gaps found in cholesterol management for young adults

Experimental intranasal vaccine triggers broad immune response against multiple strains of H5N1

New combination treatment overcomes resistance in ER positive breast cancer

Newly identified microglia subtype offers protection against Alzheimer’s disease

Galectin-3 found to drive crucial cell fusion in early placental development

Top-five pharmaceutical company expands partnership with Aptamer for multi-target Optimer® development program

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Study finds high intake of ultra-processed foods tied to reduced DNA methylation

Stress hormones may silence crucial neuronal genes through specific RNA molecules

NIH grant supports research on how the immune system responds to serious eye infections

Scientists create detailed single-cell map of the developing human brain

New $4.4 million grant funds first study of prefrontal cortical stimulation in severe bipolar disorder

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Scripps Research scientists receive NIH grant to unlock long-term HIV protection

New method enhances precision in bionic limb movement interpretation

Sensory effects of flavanols trigger physiological responses in the brain

Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer

19 NCAA women's college basketball coaches join hands to support women’s heart health

Advances in diagnosis and management of systemic light chain amyloidosis

Global Virus Network announces the addition of three new Centers of Excellence

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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