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Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Structural and molecular contributions to understanding antibody recognition of pathogenic viruses

A new review discusses how molecular and structural biology have contributed to our understanding of antibody recognition of HIV-1, SARS-CoV-2, and Zika.

1 Nov 2021

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

A team of international scientists has recently identified a distinct set of proinflammatory mediators and metabolites associated with the fatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, they have established a link between gut microbiome alteration and hyper-inflammatory response in patients with severe COVID-19. The study is currently available on the bioRxiv* preprint server.

1 Nov 2021

Protein pairs assemble based on their complementary shapes

Proteins bind to one another through a complex mix of chemical interactions. What if some proteins bind due to their shapes, a much simpler process? To answer this question, researchers used Summit, the nation's fastest supercomputer, to model lock-and-key interactions.

30 Oct 2021

Atomic-level imaging of artificial proteins

Scientists have created thin, paper-like crystalline sheets using a synthetic, protein-like molecule called a polypeptoid. These nanosheets are only one molecule thick, with the molecules arranged in very specific ways.

29 Oct 2021

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Researchers develop eToeholds for safe, effective RNA and cellular therapies

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Penn's newly created split-engineered base editors show potential for research, therapeutics

Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the Perelman School of Medicine at the University of Pennsylvania.

28 Oct 2021

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick.

28 Oct 2021

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A study of "dented" internal clocks seems to have provided evidence for a theory as to why people who work late or irregular hours are susceptible to weight gain and diabetes.

28 Oct 2021

Study unravels how cells protect against influenza A viruses

Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature Microbiology.

28 Oct 2021

A new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells.

28 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

The difference in the dynamics of SARS-COV-2 variants

A new study provides a detailed description of the varying interactions between SARS-CoV-2 and the host cell ACE-2 receptor.

27 Oct 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

McMaster-Hamburg collaboration discovers promising new antimalarial compound

A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound.

27 Oct 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

Medicines come from chemical reactions, and better chemical reactions lead to better medicines.

27 Oct 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

New study reveals how gut microbes may contribute to the beneficial effects of breastfeeding

It is widely acknowledged that breastfeeding benefits the health of infants. However, there is still a lack of solid evidence to document what happens in the gut of breastfed babies and how gut microbes may contribute to these beneficial effects.

25 Oct 2021

Molecule News and Research

Identification of common genes in COVID-19 and COPD

Structural and molecular contributions to understanding antibody recognition of pathogenic viruses

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

Protein pairs assemble based on their complementary shapes

Atomic-level imaging of artificial proteins

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Researchers develop eToeholds for safe, effective RNA and cellular therapies

Penn's newly created split-engineered base editors show potential for research, therapeutics

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

Study unravels how cells protect against influenza A viruses

A new approach to selectively turn on gene therapies in target cells

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

The difference in the dynamics of SARS-COV-2 variants

Research reveals the microbial landscape of patients with systemic lupus erythematosus

McMaster-Hamburg collaboration discovers promising new antimalarial compound

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

Study identifies how cancer cells transform macrophages into supporters of their growth

New study reveals how gut microbes may contribute to the beneficial effects of breastfeeding

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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