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Researchers develop metal-free contrast agent that could be safer for high-risk patients

To enhance the visibility of organs as they are scanned with magnetic resonance imaging (MRI), patients are usually injected with a compound known as a contrast agent before going into the scanner. The most commonly used MRI contrast agents are based on the metal gadolinium; however, these metal compounds can be harmful for young children or people with kidney problems.

13 Jul 2017

Novel approach could offer hope in treatment of inflammatory conditions

The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory conditions like arthritis, autoimmune diseases, and sepsis.

12 Jul 2017

New non-toxic elements can replace harmful lead-containing materials in electronic products

Most smartphones and other electrical or electronic products contain small amounts of lead, which doesn't sound like a big problem on its own. But when there are many billions of such products, either in daily use or gone astray, the total sums up to very large amounts of lead - which is a toxic heavy metal.

12 Jul 2017

UNC-Chapel Hill researchers find undesirable issues with widely-used drug screening tool

A widely used screening tool deployed in the early phases of drug discovery to weed out undesirable compounds is wrong so often it can't be trusted on its own, according to scientists at the University of North Carolina at Chapel Hill.

11 Jul 2017

Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

For the first time, a synthetic compound has been made that can bind to DNA in the cells' energy powerhouses, suppressing a gene associated with nerve and muscle disease.

11 Jul 2017

Natural compound found in strawberries may help prevent age-related diseases

Salk scientists have found further evidence that a natural compound in strawberries reduces cognitive deficits and inflammation associated with aging in mice.

11 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Marine natural compounds hold potential to combat tuberculosis

A team of researchers at the University of Central Florida has discovered a potential new weapon in the fight against tuberculosis, and it lives in the Little Mermaid's realm.

6 Jul 2017

Researchers find new ways to create, deliver therapies for many immune-medicated neuropathies

Researchers at LSTM are looking at new ways to create and deliver medications for a wide range of immune-medicated neuropathies, by developing new synthetic versions of the treatment currently seen as the last resort option by doctors; intravenous immunoglobulin (IVIg) therapy.

6 Jul 2017

Quantum dots may someday provide relief for eye infections

Quantum dots are transforming electronic displays on TVs and tablets. But now, one group reports in ACS Nano that these tiny structures may someday provide relief for eye infections resulting from contact lens wear, trauma or some types of surgeries.

5 Jul 2017

Study opens new range of therapeutic options for patients with atypical Rett syndrome

A translational, multicenter study carried out by research groups of the Bellvitge Biomedical Research Institute, San Juan de Dios Hospital, the University of Barcelona, Clinic Hospital, the University of Vic, Santa Creu i Sant Pau Hospital and the thematic area of Rare Diseases, has unveiled the potential of D-serine -- a dietary supplement -- to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome with severe encephalopathy.

4 Jul 2017

New technology can help fight against antimicrobial resistance

Antimicrobial resistance is a growing problem, as some infections that used to be easily cured are now immune to even our most powerful antibiotics.

4 Jul 2017

NEI-funded research aims to prevent or reverse progression of cataracts

Research funded by the National Eye Institute aims to reverse progression of cataracts- the most common cause of blindness worldwide- or to prevent them from forming altogether.

30 Jun 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

Ondek raises capital to develop new treatment for childhood allergy

Ondek, the Australian biotechnology company founded by Nobel Laureate Professor Barry Marshall, today announced it raised A$3.59 million in equity funding from professional and high-net-worth investors to support his work to develop a new treatment for childhood allergy.

30 Jun 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

Engineers take closer look at mechanical and chemical attributes of heart defect

Elastin and collagen serve as the body's building blocks. They provide tensile strength and elasticity for a number of organs, muscles and tissues. Any genetic mutation short-circuiting their function can have a devastating, and often lethal, health impact.

28 Jun 2017

Study shows septic systems as important sources of emerging contaminants in drinking water

A new analysis shows that septic systems in the United States routinely discharge pharmaceuticals, consumer product chemicals, and other potentially hazardous chemicals into the environment.

27 Jun 2017

Newly discovered antibiotic could help treat drug-resistant tuberculosis

A newly discovered antibiotic, produced by bacteria from a cystic fibrosis patient, could be used to treat cases of drug-resistant tuberculosis (TB). This is the finding of a team of scientists from Cardiff University’s School of Biosciences and the University of Warwick.

24 Jun 2017

OIST researchers create taurine-modified photosensitizer for brain cancer therapy

Photodynamic therapy is often used to treat brain tumors because of its specificity—it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells to light.

23 Jun 2017

Compound News and Research

Researchers develop metal-free contrast agent that could be safer for high-risk patients

Novel approach could offer hope in treatment of inflammatory conditions

New non-toxic elements can replace harmful lead-containing materials in electronic products

UNC-Chapel Hill researchers find undesirable issues with widely-used drug screening tool

Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

Natural compound found in strawberries may help prevent age-related diseases

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Marine natural compounds hold potential to combat tuberculosis

Researchers find new ways to create, deliver therapies for many immune-medicated neuropathies

Quantum dots may someday provide relief for eye infections

Study opens new range of therapeutic options for patients with atypical Rett syndrome

New technology can help fight against antimicrobial resistance

NEI-funded research aims to prevent or reverse progression of cataracts

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

Ondek raises capital to develop new treatment for childhood allergy

New antiviral drug candidate effective against broad range of coronaviruses

Engineers take closer look at mechanical and chemical attributes of heart defect

Study shows septic systems as important sources of emerging contaminants in drinking water

Newly discovered antibiotic could help treat drug-resistant tuberculosis

OIST researchers create taurine-modified photosensitizer for brain cancer therapy

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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