Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Bone marrow-derived cells also travel to the womb to help pregnancy

Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to research published September 12 in the open-access journal PLOS Biology.

From PLOS ONE 17 Sep 2019

New platform uses nanoparticles to deliver anti-cancer agent to cells

Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

16 Sep 2019

Scientists identify a potentially novel avenue to treat non-small cell lung cancers

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers.

13 Sep 2019

Scientists discover major regulator of schizophrenia that is active during early development

Researchers have discovered a gene that acts as a master regulator of schizophrenia during the early stages of human brain development.

12 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

New technique for autonomous coordination of cell subpopulations

For years, scientists have explored ways to alter the cells of microorganisms in efforts to improve how a wide range of products are made - including medicines, fuels, and even beer.

12 Sep 2019

CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

A gene that acts as master regulator of schizophrenia identified

Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain development.

11 Sep 2019

New strain of Streptococcus A rampant in England and Wales

According to a new study on cases of scarlet fever and other Streptococcus A infections in England and Wales, the recent rise in cases is due to a newly identified strain. This accounted for the great increase in the number of cases of scarlet fever that occurred in 2014. The last such outbreak was way back in the 1960s.

11 Sep 2019

Cell adhesion protein promotes metastasis in breast cancer, study reveals

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.

From Johns Hopkins Medicine 11 Sep 2019

Salk researchers develop method to reveal epigenetic features of brain cells

The brain's prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging.

10 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

Discovery may help identify signs of type 1 diabetes earlier

A new study showed that there are significant differences in the MHC class II antigens on the insulin peptide that is deficient in type 1 diabetes mellitus (T1DM). These determine the response of the T cells to the insulin peptide that causes destruction of insulin.

2 Sep 2019

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Brain organoids — also called mini-brains — are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments.

30 Aug 2019

The Kavli Foundation gifts $3 million to support neuroscience research at Salk

The Salk Institute announced today that The Kavli Foundation has committed $3 million to support ongoing neuroscience research at Salk as part of the joint UCSD-Salk Kavli Institute for Brain and Mind.

29 Aug 2019

[BC]2 conference focuses on use of big data in molecular medicine

From 9 to 11 September, the [BC]2 Basel Computational Biology Conference, organized by the SIB Swiss Institute of Bioinformatics, will bring together international and Swiss-based scientists working in this field, in one of the key bioinformatics events in Europe: a prime opportunity to hear from leading experts, from precision oncology to infectious diseases.

29 Aug 2019

New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Researchers study biological risk potential of nanoparticles

Nanoparticles are smaller than five nanometres - a nanometre being one millionth of a millimetre - which corresponds approximately to the size of macromolecules. Such tiny particles are very easily absorbed in body cells.

27 Aug 2019

Remodeling unhealthful gut microbiomes with the help of synthetic peptides

You are what you eat - right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer.

27 Aug 2019